Dr. Mihail Popescu |
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University of Missouri-Columbia Medicine Health Mgmt & Informatics |  |
Mailing Address324 Clark Hall Health Management and Info. Dept. University of Missouri - Columbia Columbia, Missouri 65211United States | Contact InformationPhone: (573) 882-1266 popescum@missouri.edu |
Qualifications
Ph.D., University of Missouri-Columbia, Computer Science, 2003.
M.S., University of Missouri-Columbia, Electrical Engineering, 1997.
M.S., University of Missouri-Columbia, Medical Physics, 1995.
B.S., Polytechnic Institute of Bucharest, Electrical Engineering, 1987.
Expertise and Research Interests
Goals
- Investigate similarity measures for gene products
- Research new clustering algorithm for gene products
- Investigate the linguistic similarity between clusters of gene products
- Linguistic annotation of unknown gene products
Research projects
- Similarity measures for gene products: ongoing, submitted article, applied for a research board grant (Co-PI).
Ph.D. Thesis
- New Sequence Detection Algorithms using Hidden Markov Models, 2003.
Presentations
- Popescu M., Keller J., 'E. Coli source tracking using Hidden Markov Models', poster, MC-Bios, Little Rock, AK, Nov 2003
- Popescu M., Keller J., Mitchell J.A., 'Set similarity measures for gene matching', poster, ISMB-Rocky 1, Aspen, CO, Dec 2003
- Keller J., Popescu M., Mitchell J.A., 'Gene Ontology-based Similarity Measures for Gene Clustering and Knowledge Discovery', presentation, 2003 International joint workshop on soft computing for internet and Bioinformatics, Berkeley, CA, Dec 2003.
- Investigate similarity measures for gene products
- Research new clustering algorithm for gene products
- Investigate the linguistic similarity between clusters of gene products
- Linguistic annotation of unknown gene products
Research projects
- Similarity measures for gene products: ongoing, submitted article, applied for a research board grant (Co-PI).
Ph.D. Thesis
- New Sequence Detection Algorithms using Hidden Markov Models, 2003.
Presentations
- Popescu M., Keller J., 'E. Coli source tracking using Hidden Markov Models', poster, MC-Bios, Little Rock, AK, Nov 2003
- Popescu M., Keller J., Mitchell J.A., 'Set similarity measures for gene matching', poster, ISMB-Rocky 1, Aspen, CO, Dec 2003
- Keller J., Popescu M., Mitchell J.A., 'Gene Ontology-based Similarity Measures for Gene Clustering and Knowledge Discovery', presentation, 2003 International joint workshop on soft computing for internet and Bioinformatics, Berkeley, CA, Dec 2003.
Other Expertise
Courses taken during the postdoc fellowship
- CS301 - Computational Biology
- HMI401 - Bioinformatics
- STAT410 - Statistical methods in Bioinformatics
- BIOCHEM399 - Biological Sequence Analysis
- BIOL7976 - Molecular Biology
Research Ethics Training
- HIPAA training, March 2004
- IRBtraining, March 2004
- CS301 - Computational Biology
- HMI401 - Bioinformatics
- STAT410 - Statistical methods in Bioinformatics
- BIOCHEM399 - Biological Sequence Analysis
- BIOL7976 - Molecular Biology
Research Ethics Training
- HIPAA training, March 2004
- IRBtraining, March 2004
Future Research
- automated annotation of gene products and genomes
- inferring signaling networks from methylation microarray data
- inferring signaling networks from methylation microarray data
Industrial Relevance
- Proficient using tools such as: Javascript, Java, Oracle Pl/SQL and ProC, C++, PERL, Microsoft ASP, Visual Basic, Matlab.
- Developed a content-based retrieval database for medical images implemented in Java that accesses an Oracle database. The retrieval of the images was done using a newly developed fuzzy logic method.
- Developed a database for evaluating patients with cystic fibrosis implemented using a Netscape web server and an Oracle database;
- Involved in the development of the second version of the Rural Telemedicine Evaluation Project (RTEP) using Active Server Pages and an Oracle database.
- developed methods for automated Gene Ontology annotation of gene products.
- developed methods for methylation microarray analysis
- Developed a content-based retrieval database for medical images implemented in Java that accesses an Oracle database. The retrieval of the images was done using a newly developed fuzzy logic method.
- Developed a database for evaluating patients with cystic fibrosis implemented using a Netscape web server and an Oracle database;
- Involved in the development of the second version of the Rural Telemedicine Evaluation Project (RTEP) using Active Server Pages and an Oracle database.
- developed methods for automated Gene Ontology annotation of gene products.
- developed methods for methylation microarray analysis
Keywords
COS Keywords:
Bioinformatics, Computational Biology, Computer and Information Sciences, Computer Vision, Data Mining, Fuzzy logic.Additional Terms:
Bioinformatics, Computer Science, Gene Ontology, Microarray.Languages
(Reading, Writing, Speaking)
English: (Fluent, Fluent, Fluent)
Romanian: (Fluent, Fluent, Fluent)
French: (Functional, Basic, Functional)
German: (Basic, None, Basic)
Memberships
Institute of Electrical and Electronics Engineers
International Society for Computational Biology
Honors and Awards
1984-1987,
Romanian National Scholarship,
Romanian State
Previous Positions
1997-2000, Database Programmer,
University of Missouri-Columbia,
School of Medicine,
Medical Informatics Group
1995-1997, Research Assistant,
University of Missouri-Columbia,
College of Engineering,
Electrical Engineering
1993-1995, Research Assistant,
University of Missouri-Columbia,
School of Medicine,
Radiology
1990-1993, Assistant Professor,
Bucharest Polytechnic Institute,
School of Engineering,
Electrical Engineering
Publications
- Popescu M, Keller J, Mitchell JA, Taxonomy Based Gene Product Similarity Measures, IEEE Transaction on Computational Biology and Bioinformatics, Accepted, 2005
- Popescu M, Keller J, Gader P, Linguistic Hidden Markov Models, IEEE Transaction on Fuzzy Logic, Accepted, 2005
- Popescu M, Gader P, Hidden Markov Models With Sigmoidal Memberships, IEEE Transaction Od Signal Processing, Submitted, 2005
- Gader P, Popescu M, and Ho KC, Generalized Hidden Markov Models for Landmine Detection, Proceedings of the SPIE Conference on Detection and Remediation Technologies for Mines and Mine-like Targets, V(Orlando, FL), April 2002
- Shang Y, Popescu M, Agent framework for automated radiology exam, Proceedings of SPIE Parallel and Distributed Methods for Image Processing IV, 4118(Chicago, IL), November 1999
- Popescu M, Gader P, Keller J, Klein C, Stanley J, Caldwell C, Automatic karyotyping of metaphase cells with overlapping chromosomes, Computers in Biology and Medicine, 29(1), 61-82, Jan 1999
- Popescu M, Gader P, Image Content Retrieval from Image Databases using Feature Integration by Choquet Integral, Proceedings of the SPIE Conference on Storage and Retrieval for Image and Video Databases, VII(San Jose, CA), Jan 1999
- Pickup S, Popescu M, Efficient design of pulses with trapezoidal magnitude and linear phase
response profiles, Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine., 38(1), 137-45, July 1997
Profile Details
Last Updated: 1/24/2008
COS Expertise ID #1142754
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