Prof. Patrick M. Tarwater

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Texas Tech University Health Sciences Center
Paul L. Foster School of Medicine
Biomedical Sciences
Biostatistics and Epidemiology
ProfessorAppointed: 2009
Texas Tech University Health Sciences Center
Paul L. Foster School of Medicine
Biomedical Sciences
Biostatistics and Epidemiology
ChiefAppointed: 2009
Johns Hopkins University
Bloomberg School of Public Health
Biostatistics
Adjunct Assistant ProfessorAppointed: 2002
Professional Headshot of Patrick M. Tarwater

Mailing Address

Division of Biostatistics and Epidemiology
Paul L. Foster School of Medicine
Texas Tech University Health Sciences at El Paso
4800 Alberta Drive
El Paso, Texas 79905
United States

Contact Information

Phone: (915) 545-5707
Fax: (915) 545-5716
Mobile: (915) 261-8520
patrick.tarwater@ttuhsc.edu

Qualifications

Ph.D., University of Texas Health Science Center at Houston, Biometry, 1999.
M.S., Texas Tech University, Mathematics, 1992.
B.S., Texas Tech University, Mathematics, 1990.

Expertise and Research Interests

Biostatistics
Analytic Methods for Cohort Studies
Survival Analysis
Longitudinal Data Analysis
Infectious Disease Epidemiology

Other Expertise

Center for the Analysis and Management of the Multicenter AIDS Cohort Study, Co-Investigator, 1999-2002
Women's Interagency HIV Study Data Management and Analysis Center, Co-Investigator, 1999-2002


Keywords

COS Keywords:

Applied Statistics, Biometry, Biostatistics, Epidemiology, HIV.

Additional Terms:

Cohort Studies, Longitudinal Data Analysis.

Memberships

American Statistical Association
Mathematical Association of America
Society for Epidemiologic Research

Honors and Awards

2008, Dean's Teaching Excellence Award, School of Public Health, University of Texas Health Science Center at Houston
2008-2003, Research Excellence Award, School of Public Health, University of Texas Health Science Center at Houston
2005, Outstanding Young Investigator, University of Texas Health Sciences Center at Houston
2003, Best Contributed Paper, Joint Statistical Meetings, San Francisco, American Statistical Assocaition, Teaching Statistics in the Health Sciences Section
2003, Dean's Teaching Excellence Award, School of Public Health, University of Texas Health Science Center at Houston

Previous Positions

2008-2009, Associate Professor, Texas Tech University Health Sciences Center, Paul L. Foster School of Medicine, Biomedical Sciences
2005-2008, Associate Professor, University of Texas Health Science Center at Houston, School of Public Health, Division of Biostatistics
2002-2005, Assistant Professor, University of Texas Health Science Center at Houston, School of Public Health, Division of Biostatistics
2000-2002, Assistant Research Professor, Johns Hopkins University, Bloomberg School of Public Health, Epidemiology
1999-2000, Assistant Scientist, Johns Hopkins University, Bloomberg School of Public Health, Epidemiology
1997-1999, Senior Statistical Engineer, Visual Numerics, Inc., Computational Technologies Group
1993-1997, Instructor, University of St. Thomas, Mathematics

Funding Received

  • National Institutes of Health (NIH): Mechanisms of HIV-Induced PNS Disease: The SIV/Macaque Model, $1,592,699, 2006 to 2011.
  • National Institutes of Health (NIH): Development of an SPF Macaca Nemestrina Breeding Colony, $2,701,107, 2006 to 2011.
  • National Institutes of Health (NIH): Semen in Transmission of HIV, $2,370,325, 2006 to 2011.
  • National Institutes of Health (NIH): Minocycline Inhibits Immune Reactivation of CNS SIV, $2,865,279, 2006 to 2011.
  • National Institutes of Health (NIH): Chemokine Modulation During HIV Infection and AIDS, $1,156,250, 2005 to 2010.
  • National Institutes of Health (NIH): CV-N Secreting Lactobacilli and Retrocyclin Microbicides, $4,968,332, 2005 to 2010.
  • National Institutes of Health (NIH): HIV in Semen from Infected Subjects from India, $411,995, 2005 to 2008.
  • National Institutes of Health (NIH): Neuroprotective Effects of Minocycline in Lentiviral Infection, $1,851,176, 2004 to 2009.
  • National Institutes of Health (NIH): CNS Mechanisms of MCP-1 Transcription, $1,156,250, 2004 to 2008.
  • National Institutes of Health (NIH): Viral Host Interaction in SIV Cardiac Dysfunction, $2,750,000, 2004 to 2009.
  • National Institutes of Health (NIH): Immunophilin Ligands for HIV Dementia and Neuropathy, $5,648,433, 2003 to 2007.
  • National Institutes of Health (NIH): CNS & Peripheral Reservoirs in an SIV Model of HIV HAART, $6,038,123, 2003 to 2008.

Publications

  • Ebenezer GJ, Laast VA, Dearman B, Hauer P, Tarwater PM, Adams RJ, Zink MC, McArthur JC, Mankowski JL (May 2009) Altered cutaneous nerve regeneration in a simian immunodeficiency virus / macaque intracutaneous axotomy model., The Journal of comparative neurology, 514 (3), 272-83 Abstract
  • Ding M, Tarwater P, Rodriguez M, Chatterjee R, Ratner D, Yamamura Y, Roy P, Mellors J, Neogi D, Chen Y, Gupta P (Feb 2009) Estimation of the predictive role of plasma viral load on CD4 decline in HIV-1 subtype C-infected subjects in India., Journal of acquired immune deficiency syndromes (1999), 50 (2), 119-25 Abstract
  • Sobieraj JA, Gibbs SG, Steele H, Harris MD, Tarwater PM, Ortiz M (Jan 2009) Hearing threshold comparisons between 2001-02 NHANES and 2003-05 Fort Bliss U.S. Army Service components., Military medicine, 174 (1), 42-6 Abstract
  • Makley MJ, Johnson-Greene L, Tarwater PM, Kreuz AJ, Spiro J, Rao V, Celnik PA (Jan 2009) Return of Memory and Sleep Efficiency Following Moderate to Severe Closed Head Injury., Neurorehabilitation and neural repair Abstract
  • Rodriguez MA, Ding M, Ratner D, Chen Y, Tripathy SP, Kulkarni SS, Chatterjee R, Tarwater PM, Gupta P (Jan 2009) High replication fitness and transmission efficiency of HIV-1 subtype C from India: Implications for subtype C predominance., Virology Abstract
  • Mota LC, Gibbs SG, Green CF, Flores CM, Tarwater PM, Ortiz M (Aug 2008) Seasonal fine and coarse culturable fungal constituents and concentrations from indoor and outdoor air samples taken from an arid environment., Journal of occupational and environmental hygiene, 5 (8), 511-8 Abstract
  • Mota LC, Gibbs SG, Green CF, Payan F, Tarwater PM, Ortiz M (Jun 2008) Characterization of seasonal indoor and outdoor bioaerosols in the arid environment of El Paso, Texas., Journal of environmental health, 70 (10), 48-53 Abstract
  • Qin S, Sui Y, Soloff AC, Junecko BA, Kirschner DE, Murphey-Corb MA, Watkins SC, Tarwater PM, Pease JE, Barratt-Boyes SM, Reinhart TA (Apr 2008) Chemokine and cytokine mediated loss of regulatory T cells in lymph nodes during pathogenic simian immunodeficiency virus infection., Journal of immunology (Baltimore, Md. : 1950), 180 (8), 5530-6 Abstract
  • Sivaraman K, Seshasayee A, Tarwater PM, Cole AM (Feb 2008) Codon choice in genes depends on flanking sequence information--implications for theoretical reverse translation., Nucleic acids research, 36 (3), e16 Abstract
  • Mankowski JL, Queen SE, Fernandez CS, Tarwater PM, Karper JM, Adams RJ, Kent SJ (2008) Natural host genetic resistance to lentiviral CNS disease: a neuroprotective MHC class I allele in SIV-infected macaques., PLoS ONE, 3 (11), e3603 Abstract
  • Fallert BA, Poveda S, Schaefer TM, Pfeifer ME, Sanghavi SK, Watkins SC, Murphey-Corb MA, Tarwater PM, Kirschner DE, Reinhart TA (Jan 2008) Virologic and immunologic events in hilar lymph nodes during simian immunodeficiency virus infection: development of polarized inflammation., Journal of acquired immune deficiency syndromes (1999), 47 (1), 16-26 Abstract
  • Wachtman LM, Skolasky RL, Tarwater PM, Esposito D, Schifitto G, Marder K, McDermott MP, Cohen BA, Nath A, Sacktor N, Epstein LG, Mankowski JL, McArthur JC (Sep 2007) Platelet decline: an avenue for investigation into the pathogenesis of human immunodeficiency virus -associated dementia., Archives of neurology, 64 (9), 1264-72 Abstract
  • Laast VA, Pardo CA, Tarwater PM, Queen SE, Reinhart TA, Ghosh M, Adams RJ, Zink MC, Mankowski JL (Jan 2007) Pathogenesis of simian immunodeficiency virus-induced alterations in macaque trigeminal ganglia., Journal of neuropathology and experimental neurology, 66 (1), 26-34 Abstract
  • Barber SA, Gama L, Li M, Voelker T, Anderson JE, Zink MC, Tarwater PM, Carruth LM, Clements JE (Oct 2006) Longitudinal analysis of simian immunodeficiency virus (SIV) replication in the lungs: compartmentalized regulation of SIV., The Journal of infectious diseases, 194 (7), 931-8 Abstract
  • Gibbs SG, Sobieraj J, Harris MD, Steele H, Tarwater PM, Ortiz M (Oct 2006) Comparison of nondeployable hearing profiles by Army component (Active Duty, National Guard, and Reserve) and by gender., Military medicine, 171 (10), 967-9 Abstract
  • Gibbs SG, Green CF, Tarwater PM, Mota LC, Mena KD, Scarpino PV (Jul 2006) Isolation of antibiotic-resistant bacteria from the air plume downwind of a swine confined or concentrated animal feeding operation., Environmental health perspectives, 114 (7), 1032-7 Abstract
  • Lai DJ, Tarwater PM, Hardy RJ (Jun 2006) Measuring the impact of HIV/AIDS, heart disease and malignant neoplasms on life expectancy in the USA from 1987 to 2000., Public health, 120 (6), 486-92 Abstract
  • Barber SA, Gama L, Dudaronek JM, Voelker T, Tarwater PM, Clements JE (Apr 2006) Mechanism for the establishment of transcriptional HIV latency in the brain in a simian immunodeficiency virus-macaque model., The Journal of infectious diseases, 193 (7), 963-70 Abstract
  • Wachtman LM, Tarwater PM, Queen SE, Adams RJ, Mankowski JL (Feb 2006) Platelet decline: an early predictive hematologic marker of simian immunodeficiency virus central nervous system disease., Journal of neurovirology, 12 (1), 25-33 Abstract
  • Green CF, Gibbs SG, Tarwater PM, Mota LC, Scarpino PV (Jan 2006) Bacterial plume emanating from the air surrounding swine confinement operations., Journal of occupational and environmental hygiene, 3 (1), 9-15 Abstract
  • Babas T, Dewitt JB, Mankowski JL, Tarwater PM, Clements JE, Zink MC (Jan 2006) Progressive selection for neurovirulent genotypes in the brain of SIV-infected macaques., AIDS (London, England), 20 (2), 197-205 Abstract
  • Orr ST, Newton E, Tarwater PM, Weismiller D (Sep 2005) Factors associated with prenatal smoking among black women in eastern North Carolina., Maternal and child health journal, 9 (3), 245-52 Abstract
  • Rusch ML, Farzadegan H, Tarwater PM, Safaeian M, Vlahov D, Strathdee SA (Sep 2005) Sexual risk behavior among injection drug users before widespread availability of highly active antiretroviral therapy., AIDS and behavior, 9 (3), 289-99 Abstract
  • Carruth LM, Zink MC, Tarwater PM, Miller MD, Li M, Queen LA, Mankowski JL, Shen A, Siliciano RF, Clements JE (Jun 2005) SIV-specific T lymphocyte responses in PBMC and lymphoid tissues of SIV-infected pigtailed macaques during suppressive combination antiretroviral therapy., Journal of Medical Primatology, 34 (3), 109-21 Abstract
  • Ahdieh-Grant L, Tarwater PM, Schneider MF, Anastos K, Cohen M, Khalsa A, Minkoff H, Young M, Greenblatt RM, Women's Interagency HIV Study, Factors and Temporal Trends Associated With Highly Active Antiretroviral Therapy Discontinuation in the Women's Interagency HIV Study., Journal of Acquired Immune Deficiency Syndromes (1999), 38(4), 500-3, Apr 2005 Abstract
  • Zink MC, Uhrlaub J, DeWitt J, Voelker T, Bullock B, Mankowski J, Tarwater P, Clements J, Barber S (Apr 2005) Neuroprotective and anti-human immunodeficiency virus activity of minocycline., Jama : the Journal of the American Medical Association, 293 (16), 2003-11 Abstract
  • Helke KL, Queen SE, Tarwater PM, Turchan-Cholewo J, Nath A, Zink MC, Irani DN, Mankowski JL (Mar 2005) 14-3-3 protein in CSF: an early predictor of SIV CNS disease., Journal of Neuropathology and Experimental Neurology, 64 (3), 202-8 Abstract
  • Rue SM, Roos JW, Tarwater PM, Clements JE, Barber SA (Feb 2005) Phosphorylation and proteolytic cleavage of gag proteins in budded simian immunodeficiency virus., Journal of Virology, 79 (4), 2484-92 Abstract
  • Tarwater PM, Gallant JE, Mellors JW, Gore ME, Phair JP, Detels R, Margolick JB, Munoz A, Prognostic Value of Plasma HIV RNA Among Highly Active Antiretroviral Therapy Users., Aids (london, England), 18(18), 2419-23, Dec 2004 Abstract
  • Gibbs SG, Green CF, Tarwater PM, Scarpino PV, Airborne Antibiotic Resistant and Nonresistant Bacteria and Fungi Recovered From Two Swine Herd Confined Animal Feeding Operations., Journal of Occupational and Environmental Hygiene, 1(11), 699-706, Nov 2004 Abstract
  • Philpott S, Burger H, Tarwater PM, Lu M, Gange SJ, Anastos K, Cohen M, Greenblatt RM, Kovacs A, Minkoff H, Young M, Miotti P, Dupuis M, Weiser B (Sep 2004) CCR2 genotype and disease progression in a treated population of HIV type 1-infected women., Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America., 39 (6), 861-5 Abstract
  • Barber SA, Uhrlaub JL, DeWitt JB, Tarwater PM, Zink MC, Dysregulation of mitogen-activated protein kinase signaling pathways in simian immunodeficiency virus encephalitis, American Journal of Pathology, 164(2), 355-62, Feb 2004 Abstract
  • Chatterjee R, Tarwater P, Neogi D, Ghosh A, Roy P, Sengupta S, Gupta P, Estimation of HIV seroprevalence in blood bank camps in Kolkata, India, Transfusion Medicine (oxford, England), 14(1), 77-8, Feb 2004 Abstract
  • Tarwater PM, Parish M, Gallant JE, Prolonged treatment interruption after immunologic response to highly active antiretroviral therapy, Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America., 37(11), 1541-8, December 2003 Abstract
  • Marx MA, Murugavel KG, Tarwater PM, SriKrishnan AK, Thomas DL, Solomon S, Celentano DD, Association of hepatitis C virus infection with sexual exposure in southern India, Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America., 37(4), 514-20, August 2003 Abstract
  • Li X, Buechner JM, Tarwater PM, and Muñoz A, An equiponderant graphical display of the effects of two categorical predictors on continuous outcomes, American Statistician, 57(3), 193-199, August 2003
  • Sacktor N, Skolasky RL, Tarwater PM, McArthur JC, Selnes OA, Becker J, Cohen B, Visscher B, Miller EN, Response to systemic HIV viral load suppression correlates with psychomotor speed performance, Neurology, 61(4), 567-9, August 2003 Abstract
  • Philpott S, Weiser B, Tarwater P, Vermund SH, Kleeberger CA, Gange SJ, Anastos K, Cohen M, Greenblatt RM, Kovacs A, Minkoff H, Young MA, Miotti P, Dupuis M, Chen CH, Burger H, CC Chemokine Receptor 5 Genotype and Susceptibility to Transmission of Human Immunodeficiency Virus Type 1 in Women, Journal of Infectious Diseases, 187(4), 569-75, February 2003 Abstract
  • Mankowski JL, Queen SE, Tarwater PJ, Adams RJ, Guilarte TR, Elevated peripheral benzodiazepine receptor expression in simian immunodeficiency virus encephalitis, Journal of Neurovirology, 9(1), 94-100, February 2003 Abstract
  • Babas T, Munoz D, Mankowski JL, Tarwater PM, Clements JE, Zink MC, Role of microglial cells in selective replication of simian immunodeficiency virus genotypes in the brain, Journal of Virology, 77(1), 208-16, January 2003 Abstract
  • Clements JE, Babas T, Mankowski JL, Suryanarayana K, Piatak M Jr, Tarwater PM, Lifson JD, Zink MC, The central nervous system as a reservoir for simian immunodeficiency virus (SIV): steady-state levels of SIV DNA in brain from acute through asymptomatic infection, Journal of Infectious Diseases, 186(7), 905-13, October 2002 Abstract
  • Mankowski JL, Queen SE, Tarwater PM, Fox KJ, Perry VH (Jan 2002) Accumulation of beta-amyloid precursor protein in axons correlates with CNS expression of SIV gp41., Journal of neuropathology and experimental neurology, 61 (1), 85-90 Abstract
  • Zink MC, Coleman GD, Mankowski JL, Adams RJ, Tarwater PM, Fox K, Clements JE, Increased macrophage chemoattractant protein-1 in cerebrospinal fluid precedes and predicts simian immunodeficiency virus encephalitis, Journal of Infectious Diseases, 184(8), 1015-21, October 2001 Abstract
  • Tarwater PM, Mellors J, Gore ME, Margolick JB, Phair J, Detels R, Munoz A, Methods to assess population effectiveness of therapies in human immunodeficiency virus incident and prevalent cohorts, American Journal of Epidemiology, 154(7), 675-81, October 2001 Abstract
  • Augenbraun M, Tarwater P, Greenblatt R, Cohen M, French A, Gore ME, Watts H, Preston-Martin S, Anastos K, Women's Interagency HIV Study (WIHS), Opportunistic infection prophylaxis in the women's interagency HIV study (WIHS), Journal of Acquired Immune Deficiency Syndromes (1999), 28(2), 195-6, October 2001 Abstract
  • Babas T, Vieler E, Hauer DA, Adams RJ, Tarwater PM, Fox K, Clements JE, Zink MC, Pathogenesis of SIV pneumonia: selective replication of viral genotypes in the lung, Virology, 287(2), 371-81, September 2001 Abstract
  • Tarwater, PM and Martin CF, Effects of population density on the spread of disease, Complexity, 6(6), 29-36, September 2001
  • Sacktor N, Tarwater PM, Skolasky RL, McArthur JC, Selnes OA, Becker J, Cohen B, Miller EN, Multicenter for AIDS Cohort Study (MACS), CSF antiretroviral drug penetrance and the treatment of HIV-associated psychomotor slowing, Neurology, 57(3), 542-4, August 2001 Abstract
  • Tarwater PM, Margolick JB, Jin J, Phair JP, Detels R, Rinaldo C, Giorgi J, Munoz A, Increase and plateau of CD4 T-cell counts in the 3(1/2) years after initiation of potent antiretroviral therapy, Journal of Acquired Immune Deficiency Syndromes (1999), 27(2), 168-75, June 2001 Abstract
  • Detels R, Tarwater P, Phair JP, Margolick J, Riddler SA, Munoz A, Multicenter AIDS Cohort Study, Effectiveness of potent antiretroviral therapies on the incidence of opportunistic infections before and after AIDS diagnosis, Aids (london, England), 15(3), 347-55, February 2001 Abstract
  • Makley MJ, English JB, Drubach DA, Kreuz AJ, Celnik PA, Tarwater PM, Prevalence of sleep disturbance in closed head injury patients in a rehabilitation unit., Neurorehabilitation and neural repair, 22 (4), 341-7 Abstract
  • Makley MJ, English JB, Drubach DA, Kreuz AJ, Celnik PA, Tarwater PM, Prevalence of sleep disturbance in closed head injury patients in a rehabilitation unit., Neurorehabilitation and neural repair, 22 (4), 341-7 Abstract

Profile Details

Last Updated: 6/11/2009

COS Expertise ID #934623
Reference this profile directly: http://myprofile.cos.com/ptarwater