Fred Hutchinson Cancer Research Center Public Health Sciences Division Cancer Prevention Assistant MemberAppointed: 2005 |  |
QualificationsPh.D., Stanford University, 2004. B.S., Peking University, Mathematics, 2000. Expertise and Research InterestsI am interested in various fields of bioinformatics, including modeling large-scale proteomics data in biomarker discovery studies, analyzing CGH array/microarray with statistical methods, and studying biology pathway networks based on multiple types of data. I am also collaborating with scientists in Fred Hutchinson on a range of epidemiology studies. KeywordsCOS Keywords:Bioinformatics, Biomarkers, Biostatistics, Cancer Or Carcinogenesis, Data Mining, Proteomics.Additional Terms:Bioinformatics, Data Mining, Proteomics.Languages(Reading, Writing, Speaking)Chinese, Mandarin: (Fluent, Fluent, Fluent) English: (Fluent, Fluent, Fluent) MembershipsAmerican Statistical Association Honors and Awards2000-2004,
Stanford Graduate Fellowship,
Stanford University
Previous Positions2004-2005, Postdoctoral Fellow,
Fred Hutchinson Cancer Research Center,
Public Health Sciences Division,
Biostatistics
Publications- K.A. Kwei, Y.H. Kim, L. Girard, J. Kao, M, Pacyna-Gengelbach, K. Salari, J. Lee, Y. Choi, M.Sato, P. Wang, T. Hernandez-Boussard, A.F. Gazdar, I. Petersen, J.D. Minna, J.R. Pollack (2008) Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer, Oncogene, 27 (25), 3635-30
- K. A. Kwei, Bashyam MD, J. Kao, R. Ratheesh, E. C. Reddy, Y. H. Kim, K. Montgomery, C. P.Giacomini, Y.-L. Choi, S. Chatterjee, C. A. Karikari, K. Salari, P. Wang, T. Hernandez-Boussard, G. Swarnalata, M. van de Rijn, A. Maitra, M. D. Bashyam, J. R. Pollac (2008) Genomic profiling identifies GATA6 as a lineage-specific oncogene amplified in pancreatobiliary cancer, PLOS Genetics, 4 (5), e10000081
- C. Xu, J. R. Houck, W. Fan, P. Wang, Y. Chen, M. Upton, N. D. Futran, S. M. Schwartz, L. P. Zhao, C. Chen, E. Mendez (2008) Simultaneous isolation of DNA and RNA from the same cell population obtained by laser capture microdissection for genome and transcriptome profiling, The Journal of Molecular Diagnostics, 10 (2), 129-34
- B. D. Piening, P. Wang, A. Subramanian, J. Patterson, T. Golub, E. Lander, A. Paulovich (2008) A Radiation-Derived Gene Expression Signature Predicts Clinical Outcome for Breast Cancer Patients, Radiation Research, Submitted
- J. Peng, P. Wang, N. Zhou, J. Zhu (2008) Correlation Estimation by Joint Sparse Regression Model, JASA, Submitted
- A. Paulovich, J. Whiteaker, A. Hoofnagle, P. Wang (2008) The interface between Biomarker Discovery and Clinical Validation, Proteomics
- R. Tibshirani and P. Wang (2008) smoothing and hot spot detection using the Fused Lasso, Biostaistics, 9 (1), 18-29
- P. Wang (2008) Algorithms for calling gains and losses, Microarray Analysis of the Physical Genome, Submitted (bookchapter)
- J. Whiteaker, H. Zhang, L. Zhao, P. Wang, K. S. Kelly-Spratt, R. Ivey, B. Piening, L. Feng, E. Kasarda, K. E. Gurley, J. Eng, L. Chodosh, C. J. Kemp, M. McIntosh, and A. G.. Paulovich (2007) Mass spectrometry-based identification of biomarkers relevant to human disease in a mouse model of breast cancer, Journal of Proteomics Research, 6 (10), 3962-75
- J. Lapointe1, C. Li, C. P. Giacomini1, K. Salari, S. Huang, P. Wang, M. Ferrari, T. Hernandez-Boussard, J. D. Brooks, and J. R. Pollack (2007) Genomic profiling reveals alternative genetic pathways of prostate tumorigenesis, Cancer Res., 67 (18), 8504-10
- P. Wang, M. Coram, H. Tang, M. P. Fitzgibbon, H. Zhang, E. Yi, R. Aebersold and M. Mcintosh (2007) A statistical method for chromatographic alignment of LC-MS data, Biostatistics, 8 (2), 357-67
- H. Tang, J. Peng, P. Wang, M. Coram, L. Hsu (2007) Combining Multiple Family-based Association Studies, BMC Proceedings 2007, 1 (1), S162
- J. Peng, P. Wang, Hua Tang (2007) Statistical Methods in e-QTL Mapping and Hub Identification, BMC Proceedings, 1 (1), S157
- A. Bergamaschi, Y. H. Kim, P. Wang, T. Sørlie1, T. H. Boussard, P. Lonning, R. Tibshirani, A. Børresen-Dale1, and J. R. Pollack (2006) Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer, Genes, Chromosomes, Cancer, 45 (11), 1033-40
- P. Wang, H. Tang, H. Zhang, J. Whiteaker, A. G. Paulovich and M. Mcintosh (2006) Normalization Regarding Non-random Missing Values in High-throughput Mass Spectrometry Data, Proceeding of Pacific Symposium on Biocomputing, 2006, 315-327
- R. Fang, D. A. Elias1, M. E. Monroe1, Y. Shen, M. Mcintosh, P. Wang, C. D. Goddard, S. J. Callister, R. J. Moore, Y. A. Gorby, J. N. Adkins, J. K. Fredrickson1, M. S. Lipton1, R. D. Smith1 (2006) Differential Quantitative Proteomics Analysis of Shewanella oneidensis Cultured under Aerobic and Sub-oxic Conditions by Accurate Mass and Time Tag (AMT) Approach without the Use of Stable Isotope Labeling, MCP, doi:10.1074/mcp.M500
- H. Tang, M. Coram, P. Wang, S. Choudhry, E. Burchard, N. Risch, (2006) A Markov-Hidden Markov Model for Genetic Admixture, The American Journal of Human Genetics, 79 (1), 1-12
- B. D. Piening, P. Wang, C. S. Bangur, J. Whiteaker, H. Zhang, L. Feng, J. F. Keane1, J. K. Eng, H. Tang, A. Prakash1, M. McIntosh and A. Paulovich (2006) Quality control metrics for LC-MS feature detection tools demonstrated on Saccharomyces cerevisiae proteomic profiles, Journal of Proteome Research, 5 (7), 1527-34
- M. Bellew, M. Coram, M.A. Paulovich, M. McIntosh Fitzgibbon, M. Igra, T. Randolph, P. Wang, J. Eng, A. Detter, R. Fang, C. Lin, J. Chen, D. Goodlett, J. Whiteaker, H. Zhang (2006) Informatics method for generating peptide arrays from high resolution LC-MS measurements of complex protein mixtures, Bioinformatic, 22 (15), 1902-09
- Y. H. Kim, L. Girard, C. Giacomini, P. Wang, T. Hernandez-Boussard, R. Tibshirani, J. D. Minna5, J.R. Pollack (2005) Combined microarray analysis of small cell lung cancer reveals altered apoptotic balance and distinct expression signatures of MYC family gene amplification, Oncogene, doi: 10.1038/sj.onc.
- H. Zhao, Y. Kim, P. Wang, J. Lapointe, R. Tibshirani, J. Pollack and J. Brooks (2005) Genome-wide Characterization of Gene Expression Variations and DNA Copy Number Changes in Prostate Cancer Cell Lines, Prostate, 1;63(2):187-97
- H. Tang, J. Peng, P. Wang and N. J. Risch (2005) Estimation of Individual Admixture: Analytical and Study Design Considerations, Genetic Epidemiology
- M. Bashyam, R. J. Bair, Y. H Kim, P. Wang, T. Hernandez-Boussard, C. Karikari, R. Tibshirani, A. MAITRA, J. R Pollack (2005) Array-based Comparative Genomic Hybridization Identifies Localized DNA Amplifications and Homozygous Deletions in Pancreatic Cancer, Neoplasia, 7:556-562
- M. Benetkiewicz, Y. Wang, M. Schaner, P. Wang, K.K. Mantripragada, P.G. Buckley, G. Kristensen, A. Børresen-Dale and J.P. Dumanski (2005) High-resolution gene copy number and expression profiling of human chromosome 22 in ovarian carcinomas, Genes Chromosomes Cancer, 42: 228-237
- P. Wang, Y. Kim, J. Pollack, B. Narasimhan and R. Tibshirani (2005) A method for calling gains and losses in array CGH data, Biostatistics, 6: 45-58
- P. Wang, Y. Kim, J. Pollack, R. Tibshirani (2004) Boosted PRIM with Application to Searching for Oncogenic Pathway of Lung Cancer, Proceedings of the 2004 IEEE Computational Systems Bioinformatics Conference
Profile DetailsCOS Expertise ID #1225151 Individual Expertise profile of Pei Wang, Copyright Pei Wang. © COS Expertise TM, 2009, ProQuest LLC All rights reserved. |