Roberto Adachi

(Reading, Writing, Speaking)

M. D. Anderson Cancer Center: Post-Transplantation Constrictive Bronchiolitis, $100,000, 2006 to 2008.
Mike Hogg Fund Award: Role of Allergic Inflammation in Post-Stem Cell Transplantation, $15,000, 2006 to 2007.
American Heart Association (AHA): Role of Synaptotagmin-2-Regulated Mast Cell Exocytosis in Allergic Inflammation and Innate Immunity, $130,000, 2006 to 2008.
M. D. Anderson Cancer Center: The role of mast cell exocytosis in immune responses, $1,000,000, 2003 to 2008.
Veterans Administration Advanced Research Career Award: Synaptotagmin as a calcium sensor in mast cell exocytosis, $520,000, 2001 to 2003.
Veterans Administration Merit Review Award: Synaptotagmin as a calcium sensor in mast cell exocytosis, $165,000, 2000 to 2003.
American Heart Association (AHA): Synaptotagmin as a calcium sensor in mast cell exocytosis, $120,000, 2000 to 2002.
Caroline Weiss Law Fund for Research in Molecular Medicine: Synaptotagmin as a calcium sensor in mast cell exocytosis, $25,000, 1999 to 2000.

• Thakurdas SM, Melicoff E, Sansores-Garcia L, Moreira DC, Petrova Y, Stevens RL, Adachi R (2007) The mast cell tryptase mMCP-6 has a critical immunoprotective role in bacterial infections, Journal of Biological Chemistry, In Press
• McNeil HP, Adachi R, Stevens RL (2007) Mast cell restricted tryptases: structure and function in inflammation and pathogen defense, Journal of Biological Chemistry, In Press
• Young HW, Evans CM (2007) Central Role of Muc5ac Expression in Mucous Metaplasia and Its Regulation by Conserved 5' Elements, American Journal of Respiratory Cell and Molecular Biology, In Press
• Stevens RL, Adachi R (2007) Protease-proteoglycan complexes of mouse and human mast cells, and importance of their beta tryptase-heparin complexes in inflammation and innate immunity, Immunological Reviews, 217, 155-67
• Balachandran D, Adachi R, Marom EM (2006) Invited commentary, Radiographics, 26, 39-40
• Pang ZP, Melicoff E, Padgett D, Liu Y, Dickey BF, Adachi R, Sudhof TC (2006) Synaptotagmin-2 is essential for survival and contributes to calcium-triggering of neurotransmitter release in central and neuromuscular synapses, Jounal of Neurosciences, 26, 13493-504
• Yasuda S, Morokawa N, Wong GW, Rossi A, Madhusudhan MS, Sali A, Askew YS, Adachi R, Silverman GA, Krilis SA, Stevens RL (May 2005) Urokinase-type plasminogen activator is a preferred substrate of the human epithelium serine protease tryptase epsilon/PRSS22., Blood, 105 (10), 3893-901
• Nigam R, Sepulveda J, Tuvim M, Petrova Y, Adachi R, Dickey BF, Agrawal A (Apr 2005) Expression and transcriptional regulation of Munc18 isoforms in mast cells., Biochimica Et Biophysica Acta, 1728 (1-2), 77-83
• Dhillon SS, Adachi R (Aug 2004) A 62-year-old man with shoulder pain., Chest, 126 (2), 614-6
• Adachi R, Nigam R, Dickey BF (2003) Mast cell exocytosis in airway inflammation, Therapeutic Targets of Airway Inflammation, 1st Edition, New York, NY, Marcer Dekker Inc., 327-47 pages, ISBN=0-8247-0956-X (bookchapter)
• Tuvim MJ, Adachi R, Hoffenberg S, Dickey BF (Apr 2001) Traffic control: Rab GTPases and the regulation of interorganellar transport., News in Physiological Sciences : an International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society., 16, 56-61
• Zhang BM, Kohli V, Adachi R, Lopez JA, Udden MM, Sullivan R (Mar 2001) Calmodulin binding to the C-terminus of the small-conductance Ca2+-activated K+ channel hSK1 is affected by alternative splicing., Biochemistry, 40 (10), 3189-95
• Agrawal A, Adachi R, Tuvim M, Yan XT, Teich AH, Dickey BF (Oct 2000) Gene structure and promoter function of murine Munc18-2, a nonneuronal exocytic Sec1 homolog., Biochemical and Biophysical Research Communications, 276 (3), 817-22
• Adachi R, Nigam R, Tuvim MJ, DeMayo F, Dickey BF (Jul 2000) Genomic organization, chromosomal localization, and expression of the murine RAB3D gene., Biochemical and Biophysical Research Communications, 273 (3), 877-83
• Baram D, Adachi R, Medalia O, Tuvim M, Dickey BF, Mekori YA, Sagi-Eisenberg R (May 1999) Synaptotagmin II negatively regulates Ca2+-triggered exocytosis of lysosomes in mast cells., The Journal of Experimental Medicine, 189 (10), 1649-58
• Tuvim MJ, Adachi R, Chocano JF, Moore RH, Lampert RM, Zera E, Romero E, Knoll BJ, Dickey BF (Jan 1999) Rab3D, a small GTPase, is localized on mast cell secretory granules and translocates to the plasma membrane upon exocytosis., American Journal of Respiratory Cell and Molecular Biology, 20 (1), 79-89
• Dickey BF, Adachi R (Dec 1998) Exercise-induced asthma., The New England Journal of Medicine, 339 (24), 1783-4
• Panchenko MP, Joyce-Brady M, Starikova MG, Oakes SM, Adachi R, Brody JS, Dickey BF (May 1998) Atrial natriuretic peptide modulates alveolar type 2 cell adenylyl and guanylyl cyclases and inhibits surfactant secretion., Biochimica Et Biophysica Acta, 1403 (1), 115-25
• Adachi R. (1998) Transgenic and knockout mice: their role in the study of inflammatory diseases, Resident Reporter., 3, 49-54
• Valdez H, Adachi R, Gotuzzo E (1992) KABP and other surveys: Sexual habits of university students in Lima: analysis of risk factors for the sexual transmission of HIV, A Portfolio of AIDS/STD Behavioral Interventions and Research, 1st Edition, Washington, DC, Pan American Health Organization, 274-5 pages, ISBN=9275120781 (bookchapter)
• Vidal J, Yi A, Salinas E, Valdez H, Adachi R., Yi A (1991) Relationship among blood groups and severe acute diarrhea caused by Vibrio cholerae, Revista Medica Herediana, 2, 108-11
• Valdez H, Adachi R, Gotuzzo E (1991) Sexual behavior in university students of Lima, Peru, Revista Medica Herediana, 2, 18-24
• Accinelli RA, Adachi R, Valdez LM (1991) Epidemiology of Tuberculosis in Peru, Revista de la Sociedad Peruana de Tisiologia, Neumologia y Enfermedades del Torax, 1, 13-23