Dr. Mary Anne Rossing

powered by
COS Expertise®
Fred Hutchinson Cancer Research Center
Division of Public Health Sciences
Full Member
University of Washington
School of Public Health and Community Medicine
Epidemiology
Research Associate Professor
Professional Headshot of Mary Anne Rossing

Mailing Address

Fred Hutchinson Cancer Research Center
1100 Fairview Avenue North
PO Box 19024
M4-C308
Seattle, Washington 98109
United States

Contact Information

Phone: (206) 667-4630
mrossing@fhcrc.org

Qualifications

Ph.D., University of Washington, Epidemiology, 1993.
D.V.M., University of Illinois, Veterinary Medicine, 1980.

Expertise and Research Interests

The primary focus of my research is the epidemiology of ovarian cancer. I am currently involved in studies of ovarian cancer risk in relation to use of exogenous hormones and other environmental factors. Some of my studies assess the impact of use of ovulation-inducing agents as treatment for female infertility. In other studies, I am examining the role of hormone replacement therapy, and, in particular, the impact of progestins on ovarian cancer risk. Little is known about environmental factors that may influence ovarian cancer risk, although international differences in incidence rates suggest that environmental influences may be involved. In ongoing research, I am examining whether sunlight exposure may influence ovarian cancer risk. My research also explores the interrelation of environmental and hormonal factors with genetic susceptibility to ovarian cancer. The overall goal of my ovarian cancer research is to contribute to a better understanding of pathogenic mechanisms of epithelial ovarian cancer, and to provide information eventually leading to new means of reducing the occurrence of this disease.

Keywords

COS Keywords:

Cancer or Carcinogenesis, Epidemiology, Obstetrics or Gynecology, Oncology, Public Health, Veterinary Medicine.

Publications

  • Doherty JA, Rossing MA, Cushing-Haugen KL, Chen C, Van Den Berg DJ, Wu AH, Pike MD, Et Al (2010) ESR1/SYNE1 polymorphism and invasive epithelial ovarian cancer risk: an Ovarian Cancer Association Consortium study, Cancer Epidemol Biomarkers Prev, 19 (1), 245-250
  • Rossing MA, Cushing-Haugen KL, Wicklund KG, Doherty JA, Weiss NS (2010) Recreational physical activity and risk of epithelial ovarian cancer, Cancer Causes Control, In Press
  • Rossing MA, Wicklund KG, Cushing-Haugen KL, Weiss NS (2010) Predictive value of symptoms for early detection of ovarian cancer, J Natl Cancer Inst, In Press
  • Bodelon C, Doherty JA, Chen C, Rossing MA, Weiss NS (2009) Use of nonsteroidal antiinflammatory drugs and risk of endometrial cancer, Am J Epidemiol, 170 (12), 1512-1517
  • Song H, Ramus SJ, Tyrer J, Bolton KL, Gentry-Maharaj A, Wozniak E, Anton-Culver H, Chang-Claude J, Cramer DW, DiCioccio R, Dörk T, Goode EL, Goodman MT, Schildkraut JM, Sellers T, Baglietto L, Beckmann MW, Beesley J, Blaakaer J, Carney ME, Chanock S, Chen Z, Cunningham JM, Dicks E, Doherty JA, Dürst M, Ekici AB, Fenstermacher D, Fridley BL, Giles G, Gore ME, De Vivo I, Hillemanns P, Hogdall C, Hogdall E, Iversen ES, Jacobs IJ, Jakubowska A, Li D, Lissowska J, LubiÅ,,ski J, Lurie G, McGuire V, McLaughlin J, Medrek K, Moorman PG, Moysich K, Narod S, Phelan C, Pye C, Risch H, Runnebaum IB, Severi G, Southey M, Stram DO, Thiel FC, Terry KL, Tsai YY, Tworoger SS, Van Den Berg DJ, Vierkant RA, Wang-Gohrke S, Webb PM, Wilkens LR, Wu AH, Yang H, Brewster W, Ziogas A, Houlston R, Tomlinson I, Whittemore AS, Rossing MA, Ponder BA, Pearce CL, Ness RB, Menon U, Kjaer SK, Gronwald J, Garcia-Closas M, Fasching PA, Easton DF, Chenevix-Trench G, Berchuck A, Pharoah PD, Gayther SA (2009) A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2., Nature genetics, 41 (9), 996-1000 Abstract
  • Johnatty SE, Beesley J, Chen X, Spurdle AB, Defazio A, Webb PM, Goode EL, Rider DN, Vierkant RA, Anderson S, Wu AH, Pike M, Van Den Berg D, Moysich K, Ness R, Doherty J, Rossing MA, Pearce CL, Chenevix-Trench G (2009) Polymorphisms in the FGF2 gene and risk of serous ovarian cancer: results from the ovarian cancer association consortium., Twin research and human genetics : the official journal of the International Society for Twin Studies, 12 (3), 269-75 Abstract
  • Song H, Ramus SJ, Kjaer SK, DiCioccio RA, Chenevix-Trench G, Pearce CL, Hogdall E, Whittemore AS, McGuire V, Hogdall C, Blaakaer J, Wu AH, Van Den Berg DJ, Stram DO, Menon U, Gentry-Maharaj A, Jacobs IJ, Webb PM, Beesley J, Chen X, Rossing MA, Doherty JA, Chang-Claude J, Wang-Gohrke S, Goodman MT, Lurie G, Thompson PJ, Carney ME, Ness RB, Moysich K, Goode EL, Vierkant RA, Cunningham JM, Anderson S, Schildkraut JM, Berchuck A, Iversen ES, Moorman PG, Garcia-Closas M, Chanock S, Lissowska J, Brinton L, Anton-Culver H, Ziogas A, Brewster WR, Ponder BA, Easton DF, Gayther SA, Pharoah PD (2009) Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study., Human molecular genetics, 18 (12), 2297-304 Abstract
  • McTiernan A, Wang CY, Sorensen B, Xiao L, Buist DS, Aiello Bowles EJ, White E, Rossing MA, Potter J, Urban N (2009) No effect of aspirin on mammographic density in a randomized controlled clinical trial., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 18 (5), 1524-30 Abstract
  • Quaye L, Song H, Ramus SJ, Gentry-Maharaj A, Høgdall E, DiCioccio RA, McGuire V, Wu AH, Van Den Berg DJ, Pike MC, Wozniak E, Doherty JA, Rossing MA, Ness RB, Moysich KB, Høgdall C, Blaakaer J, Easton DF, Ponder BA, Jacobs IJ, Menon U, Whittemore AS, Krüger-Kjaer S, Pearce CL, Pharoah PD, Gayther SA (2009) Tagging single-nucleotide polymorphisms in candidate oncogenes and susceptibility to ovarian cancer., British journal of cancer, 100 (6), 993-1001 Abstract
  • Pearce CL, Near AM, Van Den Berg DJ, Ramus SJ, Gentry-Maharaj A, Menon U, Gayther SA, Anderson AR, Edlund CK, Wu AH, Chen X, Beesley J, Webb PM, Holt SK, Chen C, Doherty JA, Rossing MA, Whittemore AS, McGuire V, DiCioccio RA, Goodman MT, Lurie G, Carney ME, Wilkens LR, Ness RB, Moysich KB, Edwards R, Jennison E, Kjaer SK, Hogdall E, Hogdall CK, Goode EL, Sellers TA, Vierkant RA, Cunningham JC, Schildkraut JM, Berchuck A, Moorman PG, Iversen ES, Cramer DW, Terry KL, Vitonis AF, Titus-Ernstoff L, Song H, Pharoah PD, Spurdle AB, Anton-Culver H, Ziogas A, Brewster W, Galitovskiy V, Chenevix-Trench G (2009) Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium., British journal of cancer, 100 (2), 412-20 Abstract
  • Palmieri RT, Wilson MA, Iversen ES, Clyde MA, Calingaert B, Moorman PG, Poole C, Anderson AR, Anderson S, Anton-Culver H, Beesley J, Hogdall E, Brewster W, Carney ME, Chen X, Chenevix-Trench G, Chang-Claude J, Cunningham JM, Dicioccio RA, Doherty JA, Easton DF, Edlund CK, Gayther SA, Gentry-Maharaj A, Goode EL, Goodman MT, Kjaer SK, Hogdall CK, Hopkins MP, Jenison EL, Blaakaer J, Lurie G, McGuire V, Menon U, Moysich KB, Ness RB, Pearce CL, Pharoah PD, Pike MC, Ramus SJ, Rossing MA, Song H, Terada KY, Vandenberg D, Vierkant RA, Wang-Gohrke S, Webb PM, Whittemore AS, Wu AH, Ziogas A, Berchuck A, Schildkraut JM (2008) Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women., Cancer Epidemiol Biomarkers Prev, 17 (12), 3567-72 Abstract
  • Rossing MA, Cushing-Haugen KL, Wicklund KG, Doherty JA, Weiss NS (2008) Risk of epithelial ovarian cancer in relation to benign ovarian conditions and ovarian surgery., Cancer Causes Control, 19 (10), 1357-1364 Abstract
  • Chubak J, Buist DS, Boudreau DM, Rossing MA, Lumley T, Weiss NS (2008) Breast cancer recurrence risk in relation to antidepressant use after diagnosis., Breast Cancer Res Treatment, 112 (1), 123-132 Abstract
  • Hannibal CG, Rossing MA, Wicklund KG, Cushing-Haugen KL (2008) Analgesic drug use and risk of epithelial ovarian cancer., Am J Epidemiol, 167 (12), 1430-1437 Abstract
  • Rossing MA, Cushing-Haugen KL, Doherty JA, Wicklund KG (2008) Characteristics related to the maternal intrauterine environment and risk of epithelial ovarian cancer., Ann Epidemiol, 18 (5), 411-415 Abstract
  • Rossing MA, Cushing-Haugen KL, Wicklund KG, Weiss NS (2008) Cigarette smoking and risk of epithelial ovarian cancer., Cancer Causes Control, 19 (4), 413-420 Abstract
  • Song YJ, Kristal AR, Wicklund KG, Cushing-Haugen KL, Rossing MA (2008) Coffee, tea, colas, and risk of epithelial ovarian cancer., Cancer Epidemiol Biomarkers Prev, 17 (3), 712-716 Abstract
  • Collaborative Group on Epidemiological Studies of Ovarian Cancer, Beral V, Doll R, Hermon C, Peto R, Reeves G (2008) Ovarian cancer and oral contraceptives: collaborative reanalysis of data from 45 epidemiological studies including 23,257 women with ovarian cancer and 87,303 controls., Lancet, 371 (9609), 303-314 Abstract
  • Rossing MA, Cushing-Haugen KL, Wicklund KG, Doherty JA, Weiss NS (Dec 2007) Menopausal hormone therapy and risk of epithelial ovarian cancer., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 16 (12), 2548-56 Abstract
  • Ton TG, Heckbert SR, Longstreth WT, Rossing MA, Kukull WA, Franklin GM, Swanson PD, Smith-Weller T, Checkoway H (Apr 2007) Calcium channel blockers and beta-blockers in relation to Parkinson's disease., Parkinsonism & related disorders, 13 (3), 165-9 Abstract
  • Holt SK, Rossing MA, Malone KE, Schwartz SM, Weiss NS, Chen C (Mar 2007) Ovarian cancer risk and polymorphisms involved in estrogen catabolism., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 16 (3), 481-9 Abstract
  • Dunnwald LK, Rossing MA, Li CI (2007) Hormone receptor status, tumor characteristics, and prognosis: a prospective cohort of breast cancer patients., Breast cancer research : BCR, 9 (1), R6 Abstract
  • Ton TG, Rossing MA, Bowen DJ, Srinouanprachan S, Wicklund K, Farin FM (2007) Genetic polymorphisms in dopamine-related genes and smoking cessation in women: a prospective cohort study., Behavioral and brain functions : BBF, 3, 22 Abstract
  • Ton TG, Rossing MA, Bowen DJ, Wilkerson HW, Farin FM (Jan 2007) Cholecystokinin C-45T polymorphism and smoking cessation in women., Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 9 (1), 147-51 Abstract
  • Ton TG, Heckbert SR, Longstreth WT, Rossing MA, Kukull WA, Franklin GM, Swanson PD, Smith-Weller T, Checkoway H (Jul 2006) Nonsteroidal anti-inflammatory drugs and risk of Parkinson's disease., Movement disorders : official journal of the Movement Disorder Society, 21 (7), 964-9 Abstract
  • Rossing MA, Tang MT, Flagg EW, Weiss LK, Wicklund KG, Weiss NS (Jun 2006) Body size and risk of epithelial ovarian cancer (United States)., Cancer causes & control : CCC, 17 (5), 713-20 Abstract
  • Fulton-Kehoe D, Rossing MA, Rutter C, Mandelson MT, Weiss NS (Apr 2006) Use of antidepressant medications in relation to the incidence of breast cancer., British journal of cancer, 94 (7), 1071-8 Abstract
  • Doherty JA, Weiss NS, Freeman RJ, Dightman DA, Thornton PJ, Houck JR, Voigt LF, Rossing MA, Schwartz SM, Chen C (Feb 2005) Genetic factors in catechol estrogen metabolism in relation to the risk of endometrial cancer., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 14 (2), 357-66 Abstract
  • Rossing MA, Tang MT, Flagg EW, Weiss LK, Wicklund KG (Dec 2004) A case-control study of ovarian cancer in relation to infertility and the use of ovulation-inducing drugs., American journal of epidemiology, 160 (11), 1070-8 Abstract
  • Littman AJ, Rossing MA, Madeleine MM, Tang MT, Yasui Y (2003) Association between late age at infectious mononucleosis, Epstein-Barr virus antibodies, and ovarian cancer risk., Scandinavian journal of infectious diseases, 35 (10), 728-35 Abstract
  • Dublin S, Rossing MA, Heckbert SR, Goff BA, Weiss NS, Risk of epithelial ovarian cancer in relation to use of antidepressants, benzodiazepines, and other centrally acting medications, Cancer Causes & Control : Ccc, 13(1), 35-45, February 2002 Abstract
  • Rossing MA, Remler R, Voigt LF, Wicklund KG, Daling JR, Recreational physical activity and risk of papillary thyroid cancer (United States), Cancer Causes & Control : Ccc, 12(10), 881-5, December 2001 Abstract
  • Lambe M, Rossing MA, Wuu J, Hsieh C, Breast cancer risk in women who have had children with different partners, International Journal of Cancer. Journal International Du Cancer, 93(6), 907-10, 2001 Abstract
  • Weiss NS, Rossing MA, Oestrogen-replacement therapy and risk of ovarian cancer, Lancet, 358(9280), 438, August 2001 Abstract
  • McKay JD, Lesueur F, Jonard L, Pastore A, Williamson J, Hoffman L,...Rossing MA, Toubert ME, Bonichon F, Cavarec M, Bernard AM, Boneu A, Leprat F, Haas O, Lasset C, Schlumberger M, Canzian F, Goldgar DE, Romeo G, Localization of a susceptibility gene for familial nonmedullary thyroid carcinoma to chromosome 2q21, American Journal of Human Genetics, 69(2), 440-6, August 2001 Abstract
  • Weiss NS, Rossing MA, Non-hormonal contraception and the risk of ovarian cancer, Epidemiology (cambridge, Mass.), 12(3), 300, May 2001 Abstract
  • O'Meara ES, Rossing MA, Daling JR, Elmore JG, Barlow WE, Weiss NS, Hormone replacement therapy after a diagnosis of breast cancer in relation to recurrence and mortality, Journal of the National Cancer Institute, 93(10), 754-62, May 2001 Abstract
  • Yasui Y, Potter JD, Stanford JL, Rossing MA, Winget MD, Bronner M, Daling J, Breast cancer risk and 'delayed' primary Epstein-Barr virus infection, Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 10(1), 9-16, Jan 2001 Abstract
  • Li CI, Rossing MA, Voigt LF, Daling JR, Multiple primary breast and thyroid cancers: role of age at diagnosis and cancer treatments (United States), Cancer Causes & Control : Ccc, 11(9), 805-11, October 2000 Abstract
  • Martin KM, Rossing MA, Ryland LM, DiGiacomo RF, Freitag WA, Evaluation of dietary and environmental risk factors for hyperthyroidism in cats, Journal of the American Veterinary Medical Association, 217(6), 853-6, September 2000 Abstract
  • Rossing MA, Voigt LF, Wicklund KG, Daling JR, Reproductive factors and risk of papillary thyroid cancer in women, American Journal of Epidemiology, 151(8), 765-72, April 2000 Abstract
  • Rossing MA, Scholes D, Cushing-Haugen KL, Voigt LF, Cimetidine use and risk of prostate and breast cancer, Cancer Epidemiology, Biomarkers and Prevention, 9(3), 319-23, March 2000 Abstract
  • Mockett EJ, Rossing MA, Weiss NS, Fetal antigen hypothesis and ovarian cancer: is there an immunogenic explanation for the reduction in risk associated with parity?, Epidemiology, 11(1), 55-8, Jan 2000 Abstract
  • Rossing MA, Cushing KL, Voigt LF, Wicklund KG, Daling JR, Risk of papillary thyroid cancer in women in relation to smoking and alcohol consumption, Epidemiology, 11(1), 49-54, Jan 2000 Abstract
  • Rossing MA, Daling JR, Complexity of surveillance for cancer risk associated with in-vitro fertilisation [comment], Lancet, 354(9190), 1573-4, November 1999 Abstract
  • Wittenberg J, Cook LS, Rossing MA, Weiss NS, Reproductive risk factors for mucinous and non-mucinous epithelial ovarian cancer [corrected, Epidemiology, 10(6), 761-3, November 1999 Abstract
  • Satia JA, Patterson RE, Herrero R, Jin F, Dai Q, King IB, Chen C, Kristal AR, Prentice RL, Rossing MA, Study of diet, biomarkers and cancer risk in the United States, China and Costa Rica., International Journal of Cancer, 82(1), 28-32, 2 Jul 1999 Abstract
  • Lambe M, Wuu J, Rossing MA, Hsieh CC, Twinning and maternal risk of ovarian cancer [letter], Lancet, 353(9168), 1941, June 1999 Abstract
  • Rossing MA, Genetic influences on smoking: candidate genes, Environmental Health Perspectives, 106(5), 231-8, May 1998 Abstract
  • Rossing MA, Voigt LF, Wicklund KG, Williams M, Daling JR, Use of exogenous hormones hormones and risk of papillary thyroid cancer (Washington, United States), Cancer Causes and Control, 9(3), 341-9, May 1998 Abstract
  • Weiss HA, Troisi R, Rossing MA, Brogan D, Coates RJ, Gammon MD, Potischman N, Swanson CA, Brinton LA, Fertility problems and breast cancer risk in young women: a case-control study in the United States, Cancer Causes and Control, 9(3), 331-9, May 1998 Abstract
  • Habel LA, Moe RE, Daling JR, Holte S, Rossing MA, Weiss NS, Risk of contralateral breast cancer among women with carcinoma in situ of the breast, Annals of Surgery, 225(1), 69-75, January 1997 Abstract
  • Sheppard L, Prentice RL, Rossing MA, Design considerations for estimation of exposure effects on disease risk, using aggregate data studies, Statistics in Medicine, 15(17-18), 1849-58, September 1996 Abstract
  • Rossing MA, Stanford JL, Weiss NS, Habel LA, Oral contraceptive use and risk of breast cancer in middle-aged women, American Journal of Epidemiology, 144(2), 161-4, July 1996 Abstract
  • Weiss NS, Rossing MA, Healthy screened bias in epidemiologic studies of cancer incidence, Epidemiology, 7(3), 319-22, May 1996 Abstract
  • Rossing MA, Stanford JL, Weiss NS, Daling JR, Indices of exposure to fetal and sperm antigens in relation to the occurrence of breast cancer, Epidemiology, 7(3), 309-11, May 1996 Abstract
  • Rossing MA, Daling JR, Weiss NS, Moore DE, Self SG, In situ and invasive cervical carcinoma in a cohort of infertile women, Fertility and Sterility, 65(1), 19-22, January 1996 Abstract
  • Rossing MA, Daling JR, Weiss NS, Moore DE, Self SG, Risk of breast cancer in a cohort in infertile women, Gynecologic Oncology, 60(1), 3-7, January 1996 Abstract
  • Rossing MA, Weiss NS, Fertility drugs and breast and ovarian cancer [letter; comment], Lancet, 346(8990), 1627-8, December 1995 Abstract
  • Rossing MA, Schwartz SM, Weiss NS, Thyroid cancer incidence in Asian migrants to the United States and their descendants, Cancer Causes and Control, 6(5), 439-44, September 1995 Abstract
  • Stanford JL, Weiss NS, Voigt LF, Daling JR, Habel LA, Rossing MA, Combined estrogen and progestin hormone replacement therapy in relation to risk of breast cancer in middle-aged women, Jama, 274(2), 137-42, July 1995 Abstract
  • Rossing MA, Daling JR, Weiss NS, Moore DE, Self SG, Risk of cutaneous melanoma in a cohort of infertile women, Melanoma Research, 5(2), 123-7, April 1995 Abstract
  • Habel LA, Stanford JL, Vaughan TL, Rossing MA, Voigt LF, Weiss NS, Daling JR, Occupation and breast cancer risk in middle-aged women, Journal of Occupational and Environmental Medicine, 37(3), 349-56, March 1995 Abstract
  • Basuki B, Rossing MA, Daling JR, Intrauterine device use and risk of tubal pregnancy: an Indonesian case-control study, International Journal of Epidemiology, 23(5), 1000-5, October 1994 Abstract
  • Rossing MA, Daling JR, Weiss NS, Moore DE, Self SG, Ovarian tumors in a cohort of infertile women, New England Journal of Medicine, 331(12), 771-6, September 1994 Abstract
  • Rossing MA, Daling JR, Voigt LF, Stergachis AS, Weiss NS, Current use of an intrauterine device and risk of tubal pregnancy, Epidemiology, 4(3), 252-8, May 1993 Abstract
  • Rossing MA, Daling JR, Weiss NS, Voigt LF, Stergachis AS, Wang SP, Grayston JT, Past use of an intrauterine device and risk of tubal pregnancy, Epidemiology, 4(3), 245-51, May 1993 Abstract
  • Rossing MA, Weiss NS, IUDs and pelvic inflammatory disease [letter; comment], Lancet, 340(8813), 248-9, July 1992 Abstract
  • Brunskill AJ, Rossing MA, Connell FA, Daling J, Antecedents of macrosomia, Paediatric and Perinatal Epidemiology, 5(4), 392-401, October 1991 Abstract
  • Rossing MA, Vaughan TL, McKnight B, Diet and pharyngeal cancer, International Journal of Cancer, 44(4), 593-7, October 1989 Abstract

Profile Details

Last Verified: 2/1/2010

COS Expertise ID #675799
Reference this profile directly: http://myprofile.cos.com/rossinga