Wilson Kiiza Rumbeiha

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Michigan State University
College of Veterinary Medicine
Pathobiology and Diagnostic Investigations
Associate Professor

Mailing Address

220 J DCPAH
College of Veterinary Medicine
Michigan State University
4125 Beaumont Road
Lansing, Michigan 48910-8104
United States

Contact Information

Phone: (517) 353-4773
Fax: (517) 353-4426
Rumbeiha@msu.edu

Qualifications

Ph.D., University of Guelph, Ontario, Toxicology, 1991.
B.V.M., Makerere University, Kampala, Veterinary Medicine, 1982.

Expertise and Research Interests

My current research interest is focused on investigating environmental causes of human neurodegenerative disorders, particularly Parkinson's disease. I am also interested in investigating environmental causes of mental disorders, particularly autism. My current work has led me to investigate the role of Dopamine-serotonin interaction in neurological disorders.

Other Expertise

Academic Experience:
I am board certified by the American Board of Toxicology and by the American Board of Veterinary Toxicology. I have expertise in design, supervision and interpretation of general toxicology studies in pre-clinical evaluation of pharmaceutical products or general house- hold products. I am familiar with GLP procedures and reporting of data for FDA or EPA for product approval. I have run one study according to the Japanese Ministry of Health and Welfare guidelines. I am most conversant with general toxicology studies in rodents, dogs and cats. In 1991 I was awarded the American Academy of Clinical Toxicology Research Award. In 1989 I was awarded the Roger/STB Fellowship. In 1993 I was awarded the Society of Phi Zeta Research Award.

Business Experience:
Part of my duties as a veterinary diagnostic toxicologist is to testify on the behalf of Animal Health Diagnostic Laboratory in litigation involving veterinary toxicology. I am frequently called as an expert witness in veterinary toxicology. Also part of my job is to give consultant advice to animal health care providers and citizens on any toxicology-related matters. I provide this service on a daily basis. I have also started a company, 'Toxicology Consultants International, Inc.',to provide consultation services in general and veterinary toxicology. My company is providing litigation support, data review, and project monitoring services in toxicology.

Future Research

I am interested in getting into investigating Dopamine-serotonin interactions with respect to autism and other neurological diseases.

Industrial Relevance

My new research focus on Parkisnson's disease is to develope a novel rodent model that I can use for translational research to discover new drugs for treatment of this disease. My model, a repin-induced model of neurodegeneration, has led me to explore its potential value in Autism. This model has potential to be used for translational resaerch in Autism.

Keywords

COS Keywords:

Cytokines, Microscopy, Pathology, Poison Control, Toxicology, Veterinary Medicine, Veterinary Toxicology, Xenobiotics.

Additional Terms:

Autism, Clinical Toxicologist, Diagnostic Toxicology, Food Safety, Movement Disorders, Neurodegeretaive Disorders, Parkinson's Disease, Safety Assessment, Veterinary Toxicology.

Languages

(Reading, Writing, Speaking)

English: (Fluent, Fluent, Fluent)
Nyoro: (Fluent, Fluent, Fluent)
Swahili: (Basic, Basic, Functional)

Memberships

African Society for Toxicological Sciences
American Academy of Veterinary and Comparative Toxicology
American Association of Veterinary Laboratory Diagnosticians
Society of Toxicology

Honors and Awards

The Daniel's Award, Society for Comparative Endocrinology, Michigan State University, Treatment of Vitamin D3 poisoning in dogs.

Previous Positions

1990-1994, Post-Doctoral Fellow, Kansas State University
1994-1995, Embro Corporation, Research Scientist
1995-1996, Coulston Foundation, White Sands Research Center, Study Director

Funding Received

  • A Comparative study of calcitonin and Pamidronate in Cholecalciferol-induced hypercalcemia in dogs, Internal Funding, Michigan State University, $19,000, 06/96-04/97
  • The role of inflammatory cytokines in xenobiotic-induced renal inflammation and pathology, Michigan State University, $100,000, 02/96-07/97

Publications

  • Rumbeiha WK (2007) Toxic principle of melamine/cyanuric acid nephrotoxicity in dogs and cats., , , ACVP/ASVCP Annual meeting November 2007
  • a. D. Agnew, G Maxie, M Scott, W Rumbeiha, B Hoff, B Powers (2007) Pet-food nephrotoxicity in cats and dogs: towards a case definition., ,
  • Rumbeiha WK (2007) AAVLD survey of pet food induced nephrotoxicity in North America, April to June 2007, AAVLD
  • Rumbeiha, K.W, Lin, Y.S, Oehme FW, The benefit of using methylene blue for treatment of acetaminiphen toxicity in cats., 1995
  • Rumbeiha, K.W., Gentry P.A., Bhatnagar, M.K., The effects of administration of methylmercury in combination with ethanol in the rat. Vet Human Toxicol 34:21-25, 1992
  • Rumbeiha, K.W., Oehme, F.W., Methylene blue can be used to treat methemoglobinemia in cats without inducing Heinz body hemolytic anemia. Vet Human Toxicol 34:120-122, 1992
  • Rumbeiha, W.K., Lin Yu-Shung, Oehme F.W., A dermal irritation and sensitization study in cats of Arm and Harmer Cat Litter Deodorizer. Study Report prepared for Church and Dwight Co., Inc., Princeton, NJ, 1992
  • Rumbeiha, W.K, Bhatnagar M.K., Turner, C.J., Combined effects of methylmercury and ethanol on renal metallothionein and mercury residues in rats fed restricted amounts of liquid deit. Toxicology letters, 55:279-286, 1991

Profile Details

Last Updated: 10/21/2008

COS Expertise ID #409794
Reference this profile directly: http://myprofile.cos.com/rumbeiha