Peter E. Schwartz

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Yale University
School of Medicine
Obstetrics & Gynecology
Professor/Vice-Chairman/Director, Gynecology and Oncology

Mailing Address

316 FMB
Yale University
New Haven, Connecticut
United States

Contact Information

Phone: (203) 785-4014
peter.schwartz@yale.edu

Expertise and Research Interests

Ovarian cancer is currently the fifth most common cancer in American women and the fourth most common cause of female cancer deaths. A lack of early warning symptoms and a lack of tests highly sensitive for detecting the disease are the major cause for the high death rate. My research is involved with early detection of ovarian cancer by screening a population of women who have at least one first degree relative with ovarian cancer, thereby making them at higher risk than the population at large for the disease. My research is also involved with identifying tumor markers which may be useful in early detection of ovarian cancer and in monitoring women who have themselves experienced ovarian cancer. Finally, we are interested in new and innovative ways of treating patients with ovarian cancer and are about to enroll women in a prospective trial of neoadjuvant chemotherapy.

Other Expertise

I wish to be contacted by interested students (medical, graduate or undergraduates) as a potential research mentor/thesis advisor.

Keywords

COS Keywords:

Cancer Or Carcinogenesis, Obstetrics Or Gynecology, Ovarian Cancer.

Additional Terms:

Ovarian Cancer.

Publications

  • Azodi M, Chambers SK, Rutherford TJ, Kohorn EI, Schwartz PE, Chambers JT, Adenocarcinoma in situ of the cervix: management and outcome., Gynecologic Oncology, 73(3), 348-53, June 1999 Abstract
  • Chung I, Schwartz PE, Crystal RG, Pizzorno G, Leavitt J, Deisseroth AB, Use of L-plastin promoter to develop an adenoviral system that confers transgene expression in ovarian cancer cells but not in normal mesothelial cells., Cancer Gene Therapy, 6(2), 99-106, March 1999 Abstract
  • Schwartz PE, Rutherford TJ, Chambers JT, Kohorn EI, Thiel RP, Neoadjuvant chemotherapy for advanced ovarian cancer: long-term survival., Gynecologic Oncology, 72(1), 93-9, Jan 1999 Abstract
  • Schwartz P E, SGO: a continually evolving society., Gynecologic Oncology, 70(2), 157-62, August 1998 Abstract
  • Price F V, Chambers S K, Carcangiu M L, Kohorn E I, Schwartz P E, Chambers J T, CA 125 may not reflect disease status in patients with uterine serous carcinoma., Cancer, 82(9), 1720-5, 1 May 1998 Abstract
  • Turner B C, Knisely J P, Kacinski B M, Haffty B G, Gumbs A A, Roberts K B, Frank A H, Peschel R E, Rutherford T J, Edraki B, Kohorn E I, Chambers S K, Schwartz P E, Wilson L D, Effective treatment of stage I uterine papillary serous carcinoma with high dose-rate vaginal apex radiation (192Ir) and chemotherapy., International Journal of Radiation Oncology, Biology, Physics, 40(1), 77-84, 1 Jan 1998 Abstract
  • Turner BC, Knisely JP, Kacinski BM, Haffty BG, Gumbs AA, Roberts KB, Frank AH, Peschel RE, Rutherford TJ, Edraki B, Kohorn EI, Chambers SK, Schwartz PE, Wilson LD, Effective treatment of stage I uterine papillary serous carcinoma with high dose-rate vaginal apex radiation \(192Ir\) and chemotherapy., International Journal of Radiation Oncology, Biology, Physics, 40(1), 77-84, 1 1998 Abstract
  • Chambers S K, Chambers J T, Davis C A, Kohorn E I, Schwartz P E, Lorber M I, Handschumacher R E, Pizzorno G, Pharmacokinetic and phase I trial of intraperitoneal carboplatin and cyclosporine in refractory ovarian cancer patients., Journal of Clinical Oncology, 15(5), 1945-52, May 1997 Abstract
  • Schwartz P E, Cytoreductive surgery for the management of stage IV ovarian cancer [editorial; comment], Gynecologic Oncology, 64(1), 1-3, January 1997 Abstract
  • Resnik E, Chambers S K, Carcangiu M L, Kohorn E I, Schwartz P E, Chambers I T, Malignant uterine smooth muscle tumors: role of etoposide, cisplatin, and doxorubicin (EPA) chemotherapy., Journal of Surgical Oncology, 63(3), 145-7, November 1996 Abstract
  • Schwartz P E, Hadjimichael O, Lowell D M, Merino M J, Janerich D, Rapidly progressive cervical cancer: the Connecticut experience., American Journal of Obstetrics and Gynecology, 175(4 Pt 2), 1105-9, October 1996 Abstract
  • Chambers SK, Davis CA, Schwartz PE, Kohorn EI, Chambers JT, Modulation of platinum sensitivity and resistance by cyclosporin A in refractory ovarian and fallopian tube cancer patients: a phase II study., Clinical Cancer Research, 2(10), 1693-7, October 1996 Abstract
  • Chambers SK, Davis CA, Chambers JT, Schwartz PE, Lorber MI, Hschumacher RE, Phase I trial of intravenous carboplatin and cyclosporin A in refractory gynecologic cancer patients., Clinical Cancer Research, 2(10), 1699-704, October 1996 Abstract
  • Schwartz P E, Cracchiolo B M, Cole L A, Clinical applications of urinary gonadotropin peptides (UGP) in gynecologic oncology., Anticancer Research, 16(4B), 2135-9, July 1996 Abstract
  • Fishman D A, Williams S, Small W Jr, Keh P, Gerbie M V, Schwartz P E, Gershenson D M, Lurain J RJr, Late recurrences of vaginal clear cell adenocarcinoma., Gynecologic Oncology, 62(1), 128-32, July 1996 Abstract
  • Cass I, Resnik E, Chambers J T, Chambers S K, Carcangiu M L, Kohorn E I, Schwartz P E, Combination chemotherapy with etoposide, cisplatin, and doxorubicin in mixed mullerian tumors of the adnexa., Gynecologic Oncology, 61(3), 309-14, June 1996 Abstract
  • Fishman D A, Roberts K B, Chambers J T, Kohorn E I, Schwartz P E, Chambers S K, Radiation therapy as exclusive treatment for medically inoperable patients with stage I and II endometrioid carcinoma with endometrium., Gynecologic Oncology, 61(2), 189-96, May 1996 Abstract
  • Chambers J T, Chambers S K, Kohorn E I, Carcangiu M L, Schwartz P E, Uterine papillary serous carcinoma treated with intraperitoneal cisplatin and intravenous doxorubicin and cyclophosphamide., Gynecologic Oncology, 60(3), 438-42, March 1996 Abstract
  • Cole L A, Tanaka A, Kim G S, Park S Y, Koh M W, Schwartz P E, Chambers J T, Nam J H, Beta-core fragment (beta-core/UGF/UGP), a tumor marker: a 7-year report., Gynecologic Oncology, 60(2), 264-70, February 1996 Abstract
  • Chen K C, Hsieh T T, Schwartz P E, Yang-Feng T L, Allelic deletion mapping of putative tumor suppressor genes on 17q in sporadic ovarian cancer., Journal of Obstetrics and Gynaecology, 21(6), 619-24, December 1995 Abstract
  • Smith P M, Schwartz P E, New fears in gynecologic cancer., Cancer, 76(10 Suppl), 2133-7, 15 Nov 1995 Abstract
  • Claus E B, Schwartz P E, Familial ovarian cancer. Update and clinical applications., Cancer, 76(10 Suppl), 1998-2003, 15 Nov 1995 Abstract
  • Edraki B, Schwartz P E, Operative laparoscopy and the gynecologic oncologist. Commentary and review., Cancer, 76(10 Suppl), 1987-91, 15 Nov 1995 Abstract
  • Schwartz P E, Taylor K J, Is early detection of ovarian cancer possible?, Annals of Medicine, 27(5), 519-28, October 1995 Abstract
  • Janerich D T, Hadjimichael O, Schwartz P E, Lowell D M, Meigs J W, Merino M J, Flannery J T, Polednak A P, The screening histories of women with invasive cervical cancer, Connecticut [see comments], American Journal of Public Health, 85(6), 791-4, June 1995 Abstract
  • Fishman D A, Viscarello R R, Cass I, Schwartz P E, Effect of combination chemotherapy with cisplatin and cyclophosphamide on human immunodeficiency virus type-1 surrogate markers in a patient with advanced epithelial ovarian cancer., Gynecologic Oncology, 57(1), 105-8, April 1995 Abstract
  • Resnik E, Chambers S K, Carcangiu M L, Kohorn E I, Schwartz P E, Chambers J T, A phase II study of etoposide, cisplatin, and doxorubicin chemotherapy in mixed mullerian tumors (MMT) of the uterus., Gynecologic Oncology, 56(3), 370-5, March 1995 Abstract
  • Fishman D A, Chambers S K, Schwartz P E, Kohorn E I, Chambers J T, Extramammary Paget's disease of the vulva., Gynecologic Oncology, 56(2), 266-70, February 1995 Abstract
  • Scoutt L M, McCarthy S M, Flynn S D, Lange R C, Long F, Smith R C, Chambers S K, Kohorn E, Schwartz P, Chambers J T, Clinical stage I endometrial carcinoma: pitfalls in preoperative assessment with MR imaging. Work in progress., Radiology, 194(2), 567-72, February 1995 Abstract
  • Schwartz P E, Chambers J T, Taylor K J, Early detection and screening for ovarian cancer., Journal of Cellular biochemistry. Supplement, 23, 233-7, 1995 Abstract
  • Schwartz P E, Gynecologic surveillance of women on tamoxifen., Connecticut Medicine, 58(9), 515-21, September 1994 Abstract
  • Rosman M, Hayden C L, Thiel R P, Chambers J T, Kohorn E I, Chambers S K, Schwartz P E, Prognostic indicators for poor risk epithelial ovarian carcinoma., Cancer, 74(4), 1323-8, 15 Aug 1994 Abstract
  • Schwartz P E, Academic gynecologic oncology: where are we? [editorial], Journal of The Society for Gynecologic Investigation, 1(3), 180, July 1994 Abstract
  • Scoutt L M, McCarthy S M, Lange R, Bourque A, Schwartz P E, MR evaluation of clinically suspected adnexal masses., Journal of Computer Assisted Tomography, 18(4), 609-18, July 1994 Abstract
  • Taylor K J, Schwartz P E, Screening for early ovarian cancer., Radiology, 192(1), 1-10, July 1994 Abstract
  • Chambers S K, Lamb L, Kohorn E I, Schwartz P E, Chambers J T, Chemotherapy of recurrent/advanced cervical cancer: results of the Yale University PBM-PFU protocol., Gynecologic Oncology, 53(2), 161-9, May 1994 Abstract
  • Nelson B E, Mayer A R, Tseng P C, Schwartz P E, Experience with the intravenous totally implanted port in patients with gynecologic malignancies., Gynecologic Oncology, 53(1), 98-102, April 1994 Abstract
  • Schwartz P E, Chambers J T, Makuch R, Neoadjuvant chemotherapy for advanced ovarian cancer., Gynecologic Oncology, 53(1), 33-7, April 1994 Abstract
  • Fishman D A, Schwartz P E, Current approaches to diagnosis and treatment of ovarian germ cell malignancies., Current Opinion In Obstetrics and Gynecology, 6(1), 98-104, February 1994 Abstract
  • Price F V, Chambers S K, Carcangiu M L, Kohorn E I, Schwartz P E, Chambers J T, Intravenous cisplatin, doxorubicin, and cyclophosphamide in the treatment of uterine papillary serous carcinoma (UPSC)., Gynecologic Oncology, 51(3), 383-9, December 1993 Abstract
  • Li S, Han H, Resnik E, Carcangiu M L, Schwartz P E, Yang-Feng T L, Advanced ovarian carcinoma: molecular evidence of unifocal origin., Gynecologic Oncology, 51(1), 21-5, October 1993 Abstract
  • Yang-Feng T L, Han H, Chen K C, Li S B, Claus E B, Carcangiu M L, Chambers S K, Chambers J T, Schwartz P E, Allelic loss in ovarian cancer., International Journal of Cancer, 54(4), 546-51, 19 Jun 1993 Abstract
  • Schwartz P E, The role of tumor markers in the preoperative diagnosis of ovarian cysts., Clinical Obstetrics and Gynecology, 36(2), 384-94, June 1993 Abstract
  • Magriples U, Naftolin F, Schwartz P E, Carcangiu M L, High-grade endometrial carcinoma in tamoxifen-treated breast cancer patients., Journal of Clinical Oncology, 11(3), 485-90, March 1993 Abstract
  • Price F V, Chambers S K, Chambers J T, Carcangiu M L, Schwartz P E, Kohorn E I, Stanley E R, Kacinski B M, Colony-stimulating factor-1 in primary ascites of ovarian cancer is a significant predictor of survival., American Journal of Obstetrics and Gynecology, 168(2), 520-7, February 1993 Abstract
  • Nelson B E, Rosenfield A T, Schwartz P E, Preoperative abdominopelvic computed tomographic prediction of optimal cytoreduction in epithelial ovarian carcinoma., Journal of Clinical Oncology, 11(1), 166-72, January 1993 Abstract
  • Smith P M, Schwartz P E, Social work role in an early ovarian cancer detection program., Social Work In Health Care, 19(2), 67-80, 1993 Abstract
  • Schwartz L B, Diamond M P, Schwartz P E, Leiomyosarcomas: clinical presentation., American Journal of Obstetrics and Gynecology, 168(1 Pt 1), 180-3, January 1993 Abstract
  • Mayer A R, Chambers S K, Graves E, Holm C, Tseng P C, Nelson B E, Schwartz P E, Ovarian cancer staging: does it require a gynecologic oncologist?, Gynecologic Oncology, 47(2), 223-7, November 1992 Abstract
  • Schwartz P E, The role of prophylactic oophorectomy in the avoidance of ovarian cancer., International Journal of Gynaecology and Obstetrics, 39(3), 175-84, November 1992 Abstract
  • Yang-Feng T L, Li S, Han H, Schwartz P E, Frequent loss of heterozygosity on chromosomes Xp and 13q in human ovarian cancer., International Journal of Cancer, 52(4), 575-80, 21 Oct 1992 Abstract
  • Schwartz P E, Chambers S K, Chambers J T, Kohorn E, McIntosh S, Ovarian germ cell malignancies: the Yale University experience., Gynecologic Oncology, 45(1), 26-31, April 1992 Abstract
  • D'Agostino R S, Cole L A, Ponn R B, Stern H, Schwartz P E, Urinary gonadotropin fragment measurements in patients with lung and esophageal disease., Journal of Surgical Oncology, 49(3), 147-50, March 1992 Abstract
  • Schwartz P E, Chambers J T, Taylor K J, Pellerito J, Hammers L, Cole L A, Yang-Feng T L, Smith P, Mayne S T, Makuch R, Early detection of ovarian cancer: preliminary results of the Yale Early Detection Program., Yale Journal of Biology and Medicine, 64(6), 573-82, November 1991 Abstract
  • Schwartz P E, Chambers J T, Taylor K J, Pellerito J, Hammers L, Cole L A, Yang-Feng T L, Smith P, Mayne S T, Makuch R, Early detection of ovarian cancer: background, rationale, and structure of the Yale Early Detection Program., Yale Journal of Biology and Medicine, 64(6), 557-71, November 1991 Abstract
  • Yang-Feng T L, Li S B, Leung W Y, Carcangiu M L, Schwartz P E, Trisomy 12 and K-ras-2 amplification in human ovarian tumors., International Journal of Cancer, 48(5), 678-81, 9 Jul 1991 Abstract
  • Schwartz L B, Carcangiu M L, Bradham L, Schwartz P E, Rapidly progressive squamous cell carcinoma of the cervix coexisting with human immunodeficiency virus infection: clinical opinion., Gynecologic Oncology, 41(3), 255-8, June 1991 Abstract
  • Schwartz P E, An oncologic view of when to do endoscopic surgery., Clinical Obstetrics and Gynecology, 34(2), 467-72, June 1991 Abstract
  • Schwartz P E, Ovarian masses: serologic markers., Clinical Obstetrics and Gynecology, 34(2), 423-32, June 1991 Abstract
  • Li S B, Schwartz P E, Lee W H, Yang-Feng T L, Allele loss at the retinoblastoma locus in human ovarian cancer., Journal of The National Cancer Institute, 83(9), 637-40, 1 May 1991 Abstract
  • Meyer W R, Mayer A R, Diamond M P, DeCherney A H, Schwartz P E, Litmus test for leiomyosarcoma? [letter; comment], Fertility and Sterility, 55(4), 848-9, April 1991 Abstract
  • Nam J H, Chambers J T, Schwartz P E, Cole L A, Urinary gonadotropin fragment, a new tumor marker. IV. Use in endometrial cancers and uterine mixed mullerian tumors., Gynecologic Oncology, 39(3), 352-7, December 1990 Abstract
  • Chambers S K, Chambers J T, Holm C, Peschel R E, Schwartz P E, Sequelae of lateral ovarian transposition in unirradiated cervical cancer patients., Gynecologic Oncology, 39(2), 155-9, November 1990 Abstract
  • Chambers J T, Carcangiu M L, Voynick I M, Schwartz P E, Immunohistochemical evaluation of estrogen and progesterone receptor content in 183 patients with endometrial carcinoma. Part II: Correlation between biochemical and immunohistochemical methods and su, American Journal of Clinical Pathology, 94(3), 255-60, September 1990 Abstract
  • Carcangiu M L, Chambers J T, Voynick I M, Pirro M, Schwartz P E, Immunohistochemical evaluation of estrogen and progesterone receptor content in 183 patients with endometrial carcinoma. Part I: Clinical and histologic correlations., American Journal of Clinical Pathology, 94(3), 247-54, September 1990 Abstract
  • Kier R, McCarthy S M, Scoutt L M, Viscarello R R, Schwartz P E, Pelvic masses in pregnancy: MR imaging., Radiology, 176(3), 709-13, September 1990 Abstract
  • Nam J H, Chang K C, Chambers J T, Schwartz P E, Cole L A, Urinary gonadotropin fragment, a new tumor marker. III. Use in cervical and vulvar cancers., Gynecologic Oncology, 38(1), 66-70, July 1990 Abstract
  • Leung W Y, Schwartz P E, Ng H T, Yang-Feng T L, Trisomy 12 in benign fibroma and granulosa cell tumor of the ovary., Gynecologic Oncology, 38(1), 28-31, July 1990 Abstract
  • Chambers J T, Chambers S K, Voynick I M, Schwartz P E, Neoadjuvant chemotherapy in stage X ovarian carcinoma., Gynecologic Oncology, 37(3), 327-31, June 1990 Abstract
  • Leach S D, LaMorte A I, True L D, Flynn S D, Schwartz P E, Cahow C E, Kinder B K, Aberrant hormone production from ovarian neoplasms: strategies for diagnosis and therapy., World Journal of Surgery, 14(3), 335-40; discussion 3, May 1990 Abstract
  • Cole L A, Nam J H, Chambers J T, Schwartz P E, Urinary gonadotropin fragment, a new tumor marker. II. Differentiating a benign from a malignant pelvic mass., Gynecologic Oncology, 36(3), 391-4, March 1990 Abstract
  • Nam J H, Cole L A, Chambers J T, Schwartz P E, Urinary gonadotropin fragment, a new tumor marker. I. Assay development and cancer specificity., Gynecologic Oncology, 36(3), 383-90, March 1990 Abstract
  • Meyer W R, Mayer A R, Diamond M P, Carcangiu M L, Schwartz P E, DeCherney A H, Unsuspected leiomyosarcoma: treatment with a gonadotropin-releasing hormone analogue., Obstetrics and Gynecology, 75(3 Pt 2), 529-32, March 1990 Abstract
  • Chambers J T, Chambers S K, Schwartz P E, Correlation between measured creatinine clearance and calculated creatinine clearance in ovarian cancer patients., Gynecologic Oncology, 36(1), 66-8, January 1990 Abstract
  • Hadjimichael O, Janerich D, Lowell D M, Meigs J W, Merino M J, Schwartz P E, Histologic and clinical characteristics associated with rapidly progressive invasive cervical cancer: a preliminary report from the Yale Cancer Control Research Unit., Yale Journal of Biology and Medicine, 62(4), 345-50, July 1989 Abstract
  • Schwartz P E, [Current treatment of malignant ovarian germ cell tumors], Jugoslavenska Ginekologija I Perinatologija, 29(3-4), 113-8, May 1989 Abstract

Profile Details

Last Verified: 8/1/2007

COS Expertise ID #397201
Reference this profile directly: http://myprofile.cos.com/schwartp01