Dr. Daniel R. Storm

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University of Washington
School of Medicine
Pharmacology
ProfessorAppointed: 1982

Mailing Address

Box 357750
J 681 Health Science Building
Seattle, Washington 98195-7280
United States

Contact Information

Phone: (206) 543-7028
Fax: (206) 616-8621
dstorm@u.washington.edu

Qualifications

Ph.D., University of California, Berkeley, Biochemistry, 1971.

Expertise and Research Interests

Mechanisms for Neuroplasticity

Our lab is interested in molecular mechanisms underlying neuroplasticity. Recent evidence from our lab and others suggests that the cAMP, Ca2+, and MAP kinase signal transduction pathways may contribute to various forms of neuroplasticity. In fact, cross-talk between these regulatory pathways may be particularly important for some forms of synaptic plasticity.

Learning and memory have two functionally and mechanistically distinct components: a short-term phase that lasts no more than several hours, and a long-term component that can continue for days or longer. The formation of long-term memory requires transcription of specific genes. Another property of long-term memory is a dependency on the cAMP, Ca2+, and MAP kinase signal transduction systems. LTP is an activity dependent strengthening of synaptic efficacy which may be a useful model for studying learning-induced changes in synaptic efficacy. Like learning and memory, LTP has decremental (D-LTP: 1-3 hours) and long-lasting forms (L-LTP: >3 hours). L-LTP is sensitive to inhibitors of transcription and translation. A key event in the generation of L-LTP is activation of glutamate receptors and/or voltage-sensitive calcium channels with increases in intracellular free Ca2+. This triggers a series of events required for long-term changes at the synapse including the activation of Ca2+ stimulated adenylyl cyclases. Our recent data using transgenic mouse model systems indicates that L-LTP may depend on cAMP-mediated transcription and maximal expression of CRE-mediated transcription in neurons may depend on coactivation of the Ca2+, cAMP, and MAPK signaling systems.

Specific studies in the lab include evaluation of the role of type III adenylyl cyclase for olfactory signal transduction, the role of the Ca2+ stimulated adenylyl cyclases for learning and memory and the role of adenylyl cyclases in regulation of melatonin biosynthesis and circadian rhythm. Because some long term changes in neurons and synapses depend upon increased transcription of specific genes, we are also studying mechanisms for regulation of transcription in neurons by cAMP, Ca2+ and the MAP kinase regulatory systems. Our lab uses an interdisciplinary approach for the solution of complex problems including molecular biology, electrophysiology, and behavioral neurobiology.

Other Expertise

Postdoctoral Fellow, Harvard University, Molecular Biology, 1973

Keywords

COS Keywords:

Alzheimer's Disease, Bacteria, Biochemistry, Biosynthesis, Cardiovascular Biology, Cell Biology, Circadian Rhythms, Diabetes, Electrophysiology, Endocrinologic Diseases, Endocrinology, Gene Expression, Gene Mapping, Gene Regulation, Genes, Genetic Diseases, Genetics, Gerontology, Human Learning and Memory, Infectious Diseases or Agents, Microbiology, Molecular Biology, Neurobiology, Neurons, Olfaction Or Smell, Pharmacology, Signal Transduction, Transcription, Vascular Biology.

Additional Terms:

Aging, Alzheimer's Disease, Bacteria, Bacterial Disease, Cardiac Biology, Cardiac Disease, Cardiovascular Biology, Cell Biology, Cell-Cell Interactions, Diabetes, Endocrinologic Diseases, Endocrinology, Gene, Gene Expression, Gene Mapping, Gene Regulation, Gene Structure, Genetic Approaches, Genetic Diseases, Genetics, Gerontology, Infectious Diseases, Linkage Analysis, Microbiology, Vascular Biology.

Funding Received

  • National Institutes of Health (NIH): Molecular Analysis of Signal Transduction in the Heart, $875,000, 4/30/01 to 5/1/06.
  • National Institutes of Health (NIH): Mechanisms for Neuroplasticity, $1,250,000, 2004 to 2004.
  • National Institutes of Health (NIH): Regulation of cAMP Transients in Neurons, $1,250,000, 2004 to 2004.
  • National Institutes of Health (NIH): Regulation of Pineal and Retinal Melatonin Bisynthesis, $1,125,000, 12/1/02 to 12/2/07.

Publications

  • Jackson CR, Chaurasia SS, Zhou H, Haque R, Storm DR, Iuvone PM (Apr 2009) Essential roles of dopamine D4 receptors and the type 1 adenylyl cyclase in photic control of cyclic AMP in photoreceptor cells., Journal of neurochemistry, 109 (1), 148-57 Abstract
  • DiRocco DP, Scheiner ZS, Sindreu CB, Chan GC, Storm DR (Feb 2009) A role for calmodulin-stimulated adenylyl cyclases in cocaine sensitization., The Journal of neuroscience : the official journal of the Society for Neuroscience, 29 (8), 2393-403 Abstract
  • Shan Q, Chan GC, Storm DR (Nov 2008) Type 1 adenylyl cyclase is essential for maintenance of remote contextual fear memory., The Journal of neuroscience : the official journal of the Society for Neuroscience, 28 (48), 12864-7 Abstract
  • Eckel-Mahan KL, Phan T, Han S, Wang H, Chan GC, Scheiner ZS, Storm DR (Sep 2008) Circadian oscillation of hippocampal MAPK activity and cAmp: implications for memory persistence., Nature neuroscience, 11 (9), 1074-82 Abstract
  • Krishnan V, Graham A, Mazei-Robison MS, Lagace DC, Kim KS, Birnbaum S, Eisch AJ, Han PL, Storm DR, Zachariou V, Nestler EJ (Aug 2008) Calcium-sensitive adenylyl cyclases in depression and anxiety: behavioral and biochemical consequences of isoform targeting., Biological psychiatry, 64 (4), 336-43 Abstract
  • Zachariou V, Liu R, LaPlant Q, Xiao G, Renthal W, Chan GC, Storm DR, Aghajanian G, Nestler EJ (Jun 2008) Distinct roles of adenylyl cyclases 1 and 8 in opiate dependence: behavioral, electrophysiological, and molecular studies., Biological psychiatry, 63 (11), 1013-21 Abstract
  • Sindreu CB, Storm DR (May 2008) How I learned to stop worrying and love calcineurin., Nature neuroscience, 11 (5), 527-8 Abstract
  • Zhang M, Moon C, Chan GC, Yang L, Zheng F, Conti AC, Muglia L, Muglia LJ, Storm DR, Wang H (Apr 2008) Ca-stimulated type 8 adenylyl cyclase is required for rapid acquisition of novel spatial information and for working/episodic-like memory., The Journal of neuroscience : the official journal of the Society for Neuroscience, 28 (18), 4736-44 Abstract
  • Col JA, Matsuo T, Storm DR, Rodriguez I (Jul 2007) Adenylyl cyclase-dependent axonal targeting in the olfactory system., Development (Cambridge, England), 134 (13), 2481-9 Abstract
  • Wang Z, Nudelman A, Storm DR (Jun 2007) Are pheromones detected through the main olfactory epithelium?, Molecular neurobiology, 35 (3), 317-23 Abstract
  • Shimizu K, Phan T, Mansuy IM, Storm DR (Mar 2007) Proteolytic degradation of SCOP in the hippocampus contributes to activation of MAP kinase and memory., Cell, 128 (6), 1219-29 Abstract
  • Sindreu CB, Scheiner ZS, Storm DR (Jan 2007) Ca2+ -stimulated adenylyl cyclases regulate ERK-dependent activation of MSK1 during fear conditioning., Neuron, 53 (1), 79-89 Abstract
  • Nicol X, Bennis M, Ishikawa Y, Chan GC, Repérant J, Storm DR, Gaspar P (Dec 2006) Role of the calcium modulated cyclases in the development of the retinal projections., The European journal of neuroscience, 24 (12), 3401-14 Abstract
  • Li S, Lee ML, Bruchas MR, Chan GC, Storm DR, Chavkin C (Nov 2006) Calmodulin-stimulated adenylyl cyclase gene deletion affects morphine responses., Molecular pharmacology, 70 (5), 1742-9 Abstract
  • Wang Z, Storm DR (Oct 2006) Extraction of DNA from mouse tails., BioTechniques, 41 (4), 410, 412 Abstract
  • Asyyed A, Storm D, Diamond I (Aug 2006) Ethanol activates cAMP response element-mediated gene expression in select regions of the mouse brain., Brain research, 1106 (1), 63-71 Abstract
  • Wang, Z, Sindreu,CB, Li, V, Nudelman, A, Chan, GCK, Storm, DR (2006) Pheromone detection in male mice depends on signaling through the type 3 adenylyl in the main olfactory epithelium., J. Neuroscience, 26, 997375-7379
  • Wang Z, Balet Sindreu C, Li V, Nudelman A, Chan GC, Storm DR (Jul 2006) Pheromone detection in male mice depends on signaling through the type 3 adenylyl cyclase in the main olfactory epithelium., The Journal of neuroscience : the official journal of the Society for Neuroscience, 26 (28), 7375-9 Abstract
  • Mayhan, KL (2006) Rookie snail protein LAPS veteran C/EBP: net transcriptional proceeds for long-term facilitation, Neuron, 49, 645
  • Eckel-Mahan KL, Storm DR (Mar 2006) Rookie snail protein LAPS veteran C/EBP: net transcriptional proceeds for long-term facilitation., Neuron, 49 (5), 645-6 Abstract
  • Chan GC, Tonegawa S, Storm DR (Oct 2005) Hippocampal neurons express a calcineurin-activated adenylyl cyclase., The Journal of neuroscience : the official journal of the Society for Neuroscience, 25 (43), 9913-8 Abstract
  • Wang,H, Storm,DR (2005) Ca2+-stimulated Adenylyl Cyclases and Hippocampal Neuroplasticity, Cell Science Rev., 2, 73-91
  • Livera G, Xie F, Garcia MA, Jaiswal B, Chen J, Law E, Storm DR, Conti M (May 2005) Inactivation of the mouse adenylyl cyclase 3 gene disrupts male fertility and spermatozoon function., Molecular Endocrinology (baltimore, Md.), 19 (5), 1277-90 Abstract
  • Lin, CH (2005) The dosage of the neuroD2 transcription factor regulates amygdala development and emotional learning., Proc. Natl. Acad. Sci.USA (2005), 102, 14877-14882
  • Chan, GCK, Tonegawa, S, & Storm DR, Hippocampal Neurons Express a Calcineurin-Activated Adenylyl Cyclase, J. Neuroscience, 25, 9913-9918, 2005
  • Chen, X, Garelick, M, Wang, H, Athos, J, Li, V and Daniel R. Storm, PI3 Kinase Signaling is Required for Retrieval and Extinction of Contextual Memory, Nature Neuroscience, 8, 925-931, 2005
  • Xia, Z and Storm, DR, The role of calmodulin as a signal integrator for synaptic plasticity, Nature Reviews Neuroscience, 6, 267-276, 2005
  • Garelick, MG and Storm, DR, The relationship between memory retrieval and memory extinction, Proc. Natl. Acad Sci. USA, 102, 9091-9092, 2005
  • Miwa, N and Storm, DR, Odorant-induced activation of MAP kinase in the olfactory bulb promotes survival of newly formed granule cells in the olfactory bulb., J. Neuroscience, 25, 5404-5412, 2005
  • Maas JW Jr, Vogt SK, Chan GC, Pineda VV, Storm DR, Muglia LJ, Calcium-stimulated adenylyl cyclases are critical modulators of neuronal ethanol sensitivity, J Neurosceince, 20, 4118-4126, 2005
  • Moosmang, S., Haider, N., Klubauer, N., Adelsberger, H, Langwieser, N, Muller,J, Stiess, M, Marais,E, Schulla, V, Lacinova, L, Goebbels,S, Nave, KA, Storm, DR, Hofmann, F and Kleppisch,T, Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory, J Neuroscience, 25, 9883-9892, 2005
  • Trinh K, Storm DR (Nov 2004) Detection of odorants through the main olfactory epithelium and vomeronasal organ of mice., Nutrition Reviews, 62 (11 Pt 2), S189-92; discussion Abstract
  • Fischer QS, Beaver CJ, Yang Y, Rao Y, Jakobsdottir KB, Storm DR, McKnight GS, Daw NW (Oct 2004) Requirement for the RIIbeta isoform of PKA, but not calcium-stimulated adenylyl cyclase, in visual cortical plasticity., The Journal of Neuroscience : the Official Journal of the Society for Neuroscience., 24 (41), 9049-58 Abstract
  • Ferguson GD, Storm DR (Oct 2004) Why calcium-stimulated adenylyl cyclases?, Physiology (bethesda, Md.), 19, 271-6 Abstract
  • Ferguson GD, Herschman HR, Storm DR (Sep 2004) Reduced anxiety and depression-like behavior in synaptotagmin IV (-/-) mice., Neuropharmacology, 47 (4), 604-11 Abstract
  • Wang H, Ferguson GD, Pineda VV, Cundiff PE, Storm DR, Overexpression of type-1 adenylyl cyclase in mouse forebrain enhances recognition memory and LTP, Nature Neuroscience, 7(6), 635-42, June 2004 Abstract
  • Watt WC, Sakano H, Lee ZY, Reusch JE, Trinh K, Storm DR, Odorant stimulation enhances survival of olfactory sensory neurons via MAPK and CREB, Neuron, 41(6), 955-67, 2004 Abstract
  • Fukuhara C, Liu C, Ivanova TN, Chan GC, Storm DR, Iuvone PM, Tosini G, Gating of the cAMP signaling cascade and melatonin synthesis by the circadian clock in mammalian retina, J. Neuroscience, 24(8), 1803-11, February 2004
  • Sugiura S, Kitagawa K, Omura-Matsuoka E, Sasaki T, Tanaka S, Yagita Y, Matsushita K, Storm DR, Hori M (Feb 2004) CRE-mediated gene transcription in the peri-infarct area after focal cerebral ischemia in mice., Journal of Neuroscience Research, 75 (3), 401-7 Abstract
  • Pineda, VV, Athos, JI, Wang, H, Celver, J, Ippolito, D, Boulay, B. Birnabaumer, L, and Storm, DR, Removal of Gia1 Constraints on Adenylyl Cyclase in the Hippocampus Enhances LTP and Impairs Memory Formation, Neuron, 41, 153, 5 Jan 2004
  • Wang B, Hu Q, Hearn MG, Shimizu K, Ware CB, Liggitt DH, Jin LW, Cool BH, Storm DR, Martin GM (Jan 2004) Isoform-specific knockout of FE65 leads to impaired learning and memory., Journal of Neuroscience Research, 75 (1), 12-24 Abstract
  • Ferguson GD, Wang H, Herschman HR, Storm DR (2004) Altered hippocampal short-term plasticity and associative memory in synaptotagmin IV (-/-) mice., Hippocampus, 14 (8), 964-74 Abstract
  • Wang H, Pineda VV, Chan GC, Wong ST, Muglia LJ, Storm DR, Type 8 adenylyl cyclase is targeted to excitatory synapses and required for mossy fiber long-term potentiation, J. Neuroscience, 23(30), 9710-8, October 2003
  • Poser S, Impey S, Xia Z, Storm DR, Brain-derived neurotrophic factor protection of cortical neurons from serum withdrawal-induced apoptosis is inhibited by cAMP, J. Neuroscience, 23(11), 4420-7, June 2003
  • Horner K, Livera G, Hinckley M, Trinh K, Storm D, Conti M, Rodent oocytes express an active adenylyl cyclase required for meiotic arrest, Developmental Biology, 258(2), 385-96, June 2003 Abstract
  • Trinh K, Storm DR, Vomeronasal organ detects odorants in absence of signaling through main olfactory epithelium, Nature Neuroscience, 6(5), 519-25, May 2003 Abstract
  • Shaw-Lutchman TZ, Impey S, Storm D, Nestler EJ, Regulation of CRE-mediated transcription in mouse brain by amphetamine, Synapse (New York, NY), 48(1), 10-7, April 2003
  • Wang H, Storm DR, Calmodulin-regulated adenylyl cyclases: cross-talk and plasticity in the central nervous system, Molecular Pharmacology, 63(3), 463-8, March 2003 Abstract
  • Athos, J., Impey, S., Pineda,V.P, Chen, Xi, & Storm, D. R, Hippocampal CRE-Mediated Gene Expression is Required for Contextual Memory Formation, Nature Neuroscience, 5, 1119-1120, November 2002
  • Wang H, Chan GC, Athos J, Storm DR, Synaptic concentration of type-I adenylyl cyclase in cerebellar neurons, J. Neurochem, 83(4), 946-54, November 2002
  • Wei F, Qiu CS, Kim SJ, Muglia L, Maas JW, Pineda VV, Xu HM, Chen ZF, Storm DR, Muglia LJ, Zhuo M, Genetic elimination of behavioral sensitization in mice lacking calmodulin-stimulated adenylyl cyclases, Neuron, 36(4), 713-26, November 2002 Abstract
  • Genoux D, Haditsch U, Knobloch M, Michalon A, Storm D, Mansuy IM, Protein phosphatase 1 is a molecular constraint on learning and memory, Nature, 418(6901), 970-5, Aug 2002 Abstract
  • Barrot M, Olivier JD, Perrotti LI, DiLeone RJ, Berton O, Eisch AJ, Impey S, Storm DR, Neve RL, Yin JC, Zachariou V, Nestler EJ, CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli, PNAS (USA), 99(17), 11435-40, Aug 2002 Abstract
  • Sultana R, Yu C, Yu J, Munson J, Chen D, Hua W, Estes A, Cortes F, de la Barra F, Yu D, Haider S, Trask B, Green E, Raskind W, Disteche C, Wijsman E, Dawson G, Storm D, Schellenberg G, Villacres E, Identification of a novel gene on chromosome 7q11.2 interrupted by a translocation breakpoint in a pair of autistic twins, Genomics, 80(2), 129, Aug 2002 Abstract
  • Lev-Ram V, Wong ST, Storm DR, Tsien RY, A new form of cerebellar long-term potentiation is postsynaptic and depends on nitric oxide but not cAMP, PNAS (USA), 99(12), 8389-93, June 2002 Abstract
  • Yang H, Scholich K, Poser S, Storm DR, Patel TB, Goldowitz D, Developmental expression of PAM (protein associated with MYC) in the rodent brain, Brain Research. Developmental Brain Research, 136(1), 35-42, May 2002 Abstract
  • Shaw-Lutchman TZ, Barrot M, Wallace T, Gilden L, Zachariou V, Impey S, Duman RS, Storm D, Nestler EJ, Regional and cellular mapping of cAMP response element-mediated transcription during naltrexone-precipitated morphine withdrawal, J. of Neuroscience, 22(9), 3663-72, May 2002
  • Impey S, Fong AL, Wang Y, Cardinaux JR, Fass DM, Obrietan K, Wayman GA, Storm DR, Soderling TR, Goodman RH, Phosphorylation of CBP mediates transcriptional activation by neural activity and CaM kinase IV, Neuron, 34(2), 235-44, April 2002 Abstract
  • Xia Z, Storm DR, CaRF: a neuronal transcription factor that CaREs, Neuron, 33(3), 315-6, January 2002 Abstract
  • Wong ST, Storm DR, Generation of adenylyl cyclase knockout mice, Methods in Enzymology, 345, 206-31, 2002 Abstract
  • Obrietan K, Impey S, Storm DR, cAMP response element-mediated gene expression in transgenic reporter gene mouse strain, Methods in Enzymology, 345, 570-84, 2002 Abstract
  • Mabuchi T, Kitagawa K, Kuwabara K, Takasawa K, Ohtsuki T, Xia Z, Storm D, Yanagihara T, Hori M, Matsumoto M, Phosphorylation of cAMP response element-binding protein in hippocampal neurons as a protective response after exposure to glutamate in vitro and ischemia in vivo, J. Neuroscience, 21(23), 9204-13, December 2001
  • Athos J, Storm DR (May 2001) High precision stereotaxic surgery in mice., Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.], Appendix 4, Appendix 4A Abstract
  • Pham, T.A., Rubenstein, J.L.R., Silva, A.J., Storm, D.R., and Stryker, M.P, The CRE/CREB transcriptional pathway is transiently expressed during thalamic circuit development and is required for accurate refinement of retinogeniculate axons, Neuron, 31, 409-420, 2001
  • Wong, S.T., Baker, L.P., Trinh, K., Hetman, M., Suzuki, L.A., Storm, D. R., & Bornfeld, K.E, Adenylyl cyclase 3 mediates prostaglandin E2-induced growth inhibition in arterial smooth muscle cells, Journal of Bioligical Chemistry, 276, 34206-34212, 2001
  • Chan, GCK, Lernmark, U, Xia, Z, & Daniel R. Storm, DNA Elements of the Type I Adenylyl Cyclase Gene Locus Enhance Reporter Gene Expression in Neurons and Pinealocytes, Europ. J. Neurobiol, 13, 2054-2066, 2001
  • Watt, W and Storm, D. R, Odorants stimulate the Erk/MAP kinase pathway and activate CRE-mediated transcription in olfactory sensory neurons, Journal of Biological Chemistry, 276, 2047-2052, 2001
  • Kumar PA, Baker LP, Storm DR, Bowden DM, Expression of type I adenylyl cyclase in intrinsic pathways of the hippocampal formation of the macaque (Macaca nemestrina), Neuroscience Letters, 299, 181-184, 2001
  • Poser, S. and Storm, D. R, Role of Ca2+ Stimulated Adenylyl Cyclases in LTP and Memory Formation, International Journal of Developmental Neuroscience, 19, 387-394, 2001
  • Poser, S., Impey, S., Trinh, K., Xia, Z. and Daniel R. Storm, SRF-dependent gene expression is required for mitogen-induced proliferation through a PI3 Kinase Signal Transduction Cascade, EMBO Journal, 15, 4955-4966, 2000
  • Barth, A. L., Glazewski, S., McKenna, M., Hill, P., Impey, S., Storm, D. R., and Fox, K, Upregulation of CRE-mediated gene expression during experience-dependent plasticity in adult neocortex, Journal of Neuroscience, 20, 4206-4205, 2000
  • Athos, J. and Storm, D.R, High precision Sterotaxic Surgery in mice, Current Protocols in Neuroscience, 14, A.4A.1, 2000
  • Schaefer, M.L., Wong, S.T., Wozniak, D. F., Muglia, L.M., Liauw, J.A., Nardi, A., Hartman, R. E., Vogt, S.H., Luedke, C.E., Storm, D.R., and Muglia, L. J, Altered stress-induced anxiety in adenylyl cyclase 8 deficient mice, Journal of Neuroscience, 20, 4809-4820, 2000
  • Wong, S.T., Trinh, K., Wei, J., Lowe, G., Gaggar, A., Xia, Z., Gold, G.H. and Storm, D.R, Disruption of the AC3 gene leads to peripheral and behavioral anosmia in transgenic mice, Neuron, 487-497, 2000
  • Watson, EL, Jacobson, KL, Singh, JC, Idzerda, R, Ot, SM, DiJulio, HD, Wong, ST, and Storm, DR, Type 8 adenylyl cyclase is critical for Ca2+ stimulation of cAMP accumulation in mouse parotid acicni, Journal of Biological Chemistry, 275, 14691-14699, 2000
  • Thome, J., Sakai, N., Shin, K.H., Steffen, C., Zhang, Y. J., Impey, S., Storm, D.R. and Duman, R. S, cAMP Response Element-Mediated Gene Transcription Is Upregulated by Chronic Antidepressant Treatment, Journal of Neuroscience, 20, 4030-4036, 2000
  • Wong ST, Athos J, Figueroa XA, Pineda VV, Schaefer ML, Chavkin CC, Muglia LJ, Storm DR, Calcium-stimulated adenylyl cyclase activity is critical for hippocampus-dependent long-term memory and late phase LTP, Neuron, 23(4), 787-98, August 1999
  • Obrietan K, Impey S, Smith D, Athos J, Storm DR, Circadian regulation of cAMP response element-mediated gene expression in the suprachiasmatic nuclei, Journal of Biological Chemistry, 274(25), 17748-56, 18 Jun 1999
  • Lee A, Wong ST, Gallagher D, Li B, Storm DR, Scheuer T, Catterall WA, Ca2+/calmodulin binds to and modulates P/Q-type calcium channels, Nature, 399(6732), 155-9, 13 May 1999 Abstract
  • Prichard L, Deloulme JC, Storm DR, Interactions between neurogranin and calmodulin in vivo., Journal of Biological Chemistry, 274(12), 7689-94, 19 Mar 1999 Abstract
  • Impey, S., Obrietan, K., and Storm, D. R., Making New Connections: Role of Erk/MAP Kinase Signaling in Neuronal Plasticity, Neuron, 23, 11-14, 1999
  • Obrietan, K., Impey, S., Athos, J.,and Storm, D. R., Circadian Regulation of cAMP Response Element-Mediated Gene Expression in the Suprachiasmatic Nucleus, Journal of Biological Chemistry, 274, 17748-17756, 1999
  • Lee, A. L., Wong, T., Li, B., Storm, D. R., Scheuer, T., and Catterall, W. A., Modulation of neuronal P/Q-type calcium channels by Ca2+/Calmodulin Binding to the a1a sunubit, Nature, 399, 155-159, 1999
  • Prichard, L., Deloulme, J.C., Chan, G.C.K., & Storm, D. R., Interactions Between Neurogranin and CaM in Vivo, 274, 7689-7694, 1999
  • Wong, S.T., Athos, J., Figueroa, X.A., Pineda, V., Schaefer,M.L., Chavkin C.C., Muglia, L.J.and Storm, D.R., Calcium-Stimulated Adenylyl Cyclase Activity is Critical for Hippocampus-Dependent Long-Term Memory, Neuron, 23, 787-798, 1999
  • Baker, LP, Nielsen, MD, Impey, S, Hacker, BM, Poser, SW, Chan, M, and Storm, DR, Regulation and Immunohistochemical Localization of bg-Stimulated Adenylyl Cyclases in Mouse Hippocampus, Journal of Neuroscience, 19, 180-192, 1999
  • Pham TA, Impey S, Storm DR, Stryker MP, CRE-mediated gene transcription in neocortical neuronal plasticity during the developmental critical period., Neuron, 22(1), 63-72, Jan 1999 Abstract
  • Baker LP, Nielsen MD, Impey S, Hacker BM, Poser SW, Chan MY, Storm DR, Regulation and immunohistochemical localization of betagamma-stimulated adenylyl cyclases in mouse hippocampus., Journal of Neuroscience, 19(1), 180-92, 1 Jan 1999 Abstract
  • Obrietan K, Impey S, Storm DR, Light and circadian rhythmicity regulate MAP kinase activation in the suprachiasmatic nuclei., Nat. Neurosci., 1(8), 693-700, December 1998 Abstract
  • Feil IK, Platas AA, van den Akker F, Reddy R, Merritt EA, Storm DR, Hol WG, Stepwise transplantation of an active site loop between heat-labile enterotoxins LT-II and LT-I and characterization of the obtained hybrid toxins., Protein Engineering, 11(11), 1103-9, November 1998 Abstract
  • Impey S, Smith DM, Obrietan K, Donahue R, Wade C, Storm DR, Stimulation of cAMP response element \(CRE\)-mediated transcription during contextual learning, Nat. Neurosci., 1(7), 595-601, November 1998 Abstract
  • Chan G C, Hinds T R, Impey S, Storm D R, Hippocampal neurotoxicity of Delta9-tetrahydrocannabinol., Journal of Neuroscience, 18(14), 5322-32, 15 Jul 1998 Abstract
  • Storm D R, Hansel C, Hacker B, Parent A, Linden D J, Impaired cerebellar long-term potentiation in type I adenylyl cyclase mutant mice., Neuron, 20(6), 1199-210, June 1998 Abstract
  • Hacker BM, Tomlinson JE, Wayman GA, Sultana R, Chan G, Villacres E, Disteche C, Storm DR, Cloning, chromosomal mapping, and regulatory properties of the human type 9 adenylyl cyclase \(ADCY9\)., Genomics, 50(1), 97-104, 15 May 1998 Abstract
  • Tan X, Wong S T, Ghebrehiwet B, Storm D R, Bordin S, Complement C1q inhibits cellular spreading and stimulates adenylyl cyclase activity of fibroblasts., Clinical Immunology and Immunopathology, 87(2), 193-204, May 1998 Abstract
  • Villacres E C, Wong S T, Chavkin C, Storm D R, Type I adenylyl cyclase mutant mice have impaired mossy fiber long-term potentiation., Journal of Neuroscience, 18(9), 3186-94, 1 May 1998 Abstract
  • Wei, J., Impey, S., Zhao, A.Z., Chan, G.C.K., Baker, L.P., Beavo, J.A. and Storm, D. R., Phosphorylation and Inhibition of Olfactory Adenylyl Cyclase by CaM Kinase II in Olfactory Sensory Neurons: A Mechanism for Attenuation of Olfactory Signals, Neuron, 21, 495-504, 1998
  • Impey, S., Smith, D. M., Obrietan, K., Donahue, R., Wade, C., and Storm, D. R., Stimulation of cAMP Response Element (CRE)-Mediated Transcription During Contextual Learning, Nature Neuroscience, 1(7), 595-601, 1998
  • Impey,S., Obrietan, K., Wong,S. T., Poser, S., Yano,S., Wayman, G., Deloulme, J. C., Chan,G. and Daniel R. Storm, Crosstalk Between ERK and PKA Is Required for Ca2+ Stimulation of CREB-Dependent Transcription and ERK Nuclear Translocation, Neuron, 21, 869-883, 1998
  • Storm, D. R., Hansel, C., Hacker, B., Parent, A., and Linden, D. J., Impaired cerebellar LTP in type I adenylyl cyclase mutant mice, Neuron, 20, 1199-1210, 1998
  • Abdel-Majidl, R. M., Leong, W. L., Schalkwyk, L.C., Smallman, D.S., Wong, S. T., Storm. D. R., Fine, A., Dobson, M. J., Guernsey, D. L. and Neuroman, P. E., Loss of adenylyl cyclase I activity disrupts patterning of mouse somatosensory cortex, Nature Genetics, 19, 289-291, 1998
  • Baker, L.P., Nielsen, M.D., Impey, S., MetcalfÝ, M. A., Poser, S.W., Chan, G., Obrietan, K., Hamblin, M.W., and Storm, D. R., Stimulation of Type 1 and Type 8 Ca2+/Calmodulin-sensitive Adenylyl Cyclases by the Gs-coupled 5-Hydroxytryptamine Subtype 5-HT7A Receptor, Journal of Biological Chemistry, 273, 17469-17476, 1998
  • Villacres, E. C., Wong, S.T., Chavkin, C., and Storm, D. R., Type I adenylyl cyclase mutant mice have impaired mossy fiber LTP, Journal of Neuroscience, 18, 3186-3194, 1998
  • Hacker, B.M., Tomlinson, J.E., Wayman,G.S., Sultana, R., Chan, G., Villacres, E., Disteche, C., and Storm, D.R., Cloning, chromosomalmapping, and regulatory properties of the human type 9 adenylyl cyclase, Genomics, 50, 97-104, 1998
  • Jun, K.S., Choi, G., Yang, S. G., Kim, N.K., Choi, K. Y., Kim, H., Chan, C. K., Storm, D. R., Albert, C., Mayr, G. W., Lee, C., and Shin, H., Dissoication of enhanced hippocampal CA1 LTP and spatial learning in inositol 1,4,5-triphosphate 3-kinase (a) deficient mice, Learning and Memory, 5, 317-330, 1998
  • Watson, E.L., Wu, Z.L., Jacobson, K.L., Storm, D. R., Singh, J. C. and Ott, S.M., Capacitative Ca2+ entry is involved in cAMP synthesis in mouse parotid acini, American Journal of Physiology, 43, C557-C565, 1998
  • Watson EL, Wu Z, Jacobson KL, Storm DR, Singh JC, Ott SM, Capacitative Ca2+ entry is involved in cAMP synthesis in mouse parotid acini, American Journal of Physiology, 274(3 Pt 1), C557-65, 1998 Abstract
  • Chan, G.C.C., Hinds, T. R., Impey, S., and Storm, D. R., Hippocampal neurotoxicity of *9-Tetrahydrocannabinol, Journal of Neuroscience, 18, 5322-5332, 1998
  • Deloulme J C, Prichard L, Delattre O, Storm D R, The prooncoprotein EWS binds calmodulin and is phosphorylated by protein kinase C through an IQ domain, Journal of Biological Chemistry, 272(43), 27369-77, 24 Oct 1997 Abstract
  • Baker L P, Storm D R, Dynamic palmitoylation of neuromodulin (GAP-43) in cultured rat cerebellar neurons and mouse N1E-115 cells, Neuroscience Letters, 234(2-3), 156-60, 3 Oct 1997 Abstract
  • Dittman A H, Quinn T P, Nevitt G A, Hacker B, Storm D R, Sensitization of olfactory guanylyl cyclase to a specific imprinted odorant in coho salmon, Neuron, 19(2), 381-9, August 1997 Abstract
  • Mark M D, Storm D R, Coupling of epidermal growth factor (EGF) with the antiproliferative activity of cAMP induces neuronal differentiation, Journal of Biological Chemistry, 272(27), 17238-44, 4 Jul 1997 Abstract
  • Xia Z, Storm D R, Calmodulin-regulated adenylyl cyclases and neuromodulation, Current Opinion In Neurobiology, 7(3), 391-6, June 1997 Abstract
  • Silva, A., Simpson, E., Takahashi, J., Lipp, H., Nakanishi, N., Wehner, J., Giese, K., Tully, T., Abel, T., Chapman, P, Fox, K., Grant, S., Lathe, R., Mayford, M., McNamara, J., Morris, R, Picciotto, M., Shin, H, Slesinger, P., Storm, D., Stryker, M., W, Mutrant mice and neuroscience: recommendations concerning genetic background, Neuron, 19, 755-759, 1997
  • Mark, M. D. and Storm. D. R., The antiprolferative activity of KCl contributes to EGF-induced neurite outgrowth in PC12 cells, Neuroscience Letters, 230, 73-76, 1997
  • Nielsen M D, Chan G CK, Poser S W, Storm D R, Differential regulation of type I and type VIII Ca2+-stimulated adenylyl cyclases by Gi-coupled receptors in vivo, Journal of Biological Chemistry, 271(52), 33308-16, 27 Dec 1996 Abstract
  • Wayman G A, Wei J, Wong S, Storm D R, Regulation of type I adenylyl cyclase by calmodulin kinase IV in vivo, Molecular and Cellular Biology, 16(11), 6075-82, November 1996 Abstract
  • Wei J, Wayman G, Storm D R, Phosphorylation and inhibition of type III adenylyl cyclase by calmodulin-dependent protein kinase II in vivo, Journal of Biological Chemistry, 271(39), 24231-5, 27 Sep 1996 Abstract
  • Impey S, Mark M, Villacres E C, Poser S, Chavkin C, Storm D R, Induction of CRE-mediated gene expression by stimuli that generate long-lasting LTP in area CA1 of the hippocampus, Neuron, 16(5), 973-82, May 1996 Abstract
  • Feil I K, Reddy R, de Haan L, Merritt E A, van den Akker F, Storm D R, Hol W G, Protein engineering studies of A-chain loop 47-56 of Escherichia coli heat-labile enterotoxin point to a prominent role of this loop for cytotoxicity, Molecular Microbiology, 20(4), 823-32, May 1996 Abstract
  • Wayman G A, Hinds T R, Storm D R, Hormone stimulation of type III adenylyl cyclase induces Ca2+ oscillations in HEK-293 cells, Journal of Biological Chemistry, 270(41), 24108-15, 13 Oct 1995 Abstract
  • Wayman G A, Impey S, Storm D R, Ca2+ inhibition of type III adenylyl cyclase in vivo, Journal of Biological Chemistry, 270(37), 21480-6, 15 Sep 1995 Abstract
  • Mark M D, Liu Y, Wong S T, Hinds T R, Storm D R, Stimulation of neurite outgrowth in PC12 cells by EGF and KCl depolarization: a Ca(2+)-independent phenomenon, Journal of Cell Biology, 130(3), 701-10, August 1995 Abstract
  • Reddy R, Smith D, Wayman G, Wu Z, Villacres E C, Storm D R, Voltage-sensitive adenylyl cyclase activity in cultured neurons. A calcium-independent phenomenon, Journal of Biological Chemistry, 270(24), 14340-6, 16 Jun 1995 Abstract
  • Villacres E C, Wu Z, Hua W, Nielsen M D, Watters J J, Yan C, Beavo J, Storm D R, Developmentally expressed Ca(2+)-sensitive adenylyl cyclase activity is disrupted in the brains of type I adenylyl cyclase mutant mice, Journal of Biological Chemistry, 270(24), 14352-7, 16 Jun 1995 Abstract
  • Edelhoff S, Villacres E C, Storm D R, Disteche C M, Mapping of adenylyl cyclase genes type I, II, III, IV, V, and VI in mouse, Mammalian Genome, 6(2), 111-3, February 1995 Abstract
  • Wu Z L, Thomas S A, Villacres E C, Xia Z, Simmons M L, Chavkin C, Palmiter R D, Storm D R, Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice, Proceedings of the National Academy of Sciences (USA), 92(1), 220-4, 3 Jan 1995 Abstract
  • Wu ZL, Thomas SA, Villacres EC, Xia Z, Simmons ML, Chavkin C, Palmiter RD, Storm DR, Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice., Proceedings of the National Academy of Sciences (USA), 92(1), 220-4, 3 1995 Abstract
  • Impey S, Wayman G, Wu Z, Storm D R, Type I adenylyl cyclase functions as a coincidence detector for control of cyclic AMP response element-mediated transcription: synergistic regulation of transcription by Ca2+ and isoproterenol, Molecular and Cellular Biology, 14(12), 8272-81, December 1994 Abstract
  • Buelt M K, Glidden B J, Storm D R, Regulation of p68 RNA helicase by calmodulin and protein kinase C, Journal of Biological Chemistry, 269(47), 29367-70, 25 Nov 1994 Abstract
  • Wayman G A, Impey S, Wu Z, Kindsvogel W, Prichard L, Storm D R, Synergistic activation of the type I adenylyl cyclase by Ca2+ and Gs-coupled receptors in vivo, Journal of Biological Chemistry, 269(41), 25400-5, 14 Oct 1994 Abstract
  • Liu Y, Fisher D A, Storm D R, Intracellular sorting of neuromodulin (GAP-43) mutants modified in the membrane targeting domain, Journal of Neuroscience, 14(10), 5807-17, October 1994 Abstract
  • Duhe R J, Nielsen M D, Dittman A H, Villacres E C, Choi E J, Storm D R, Oxidation of critical cysteine residues of type I adenylyl cyclase by o-iodosobenzoate or nitric oxide reversibly inhibits stimulation by calcium and calmodulin, Journal of Biological Chemistry, 269(10), 7290-6, 11 Mar 1994 Abstract
  • Dittman A H, Weber J P, Hinds T R, Choi E J, Migeon J C, Nathanson N M, Storm D R, A novel mechanism for coupling of m4 muscarinic acetylcholine receptors to calmodulin-sensitive adenylyl cyclases: crossover from G protein-coupled inhibition to stimulation, Biochemistry, 33(4), 943-51, 1 Feb 1994 Abstract
  • Liu Y, Fisher D A, Storm D R, Analysis of the palmitoylation and membrane targeting domain of neuromodulin (GAP-43) by site-specific mutagenesis, Biochemistry, 32(40), 10714-9, 12 Oct 1993 Abstract
  • Oldenburg D J, Storm D R, Identification of a domain in Bordetella pertussis adenylyl cyclase important for subunit interactions and cell invasion activity, Microbial Pathogenesis, 15(2), 153-7, August 1993 Abstract
  • Oldenburg D J, Gross M K, Smith A L, Storm D R, Virulence of a Bordetella pertussis strain expressing a mutant adenylyl cyclase with decreased calmodulin affinity, Microbial Pathogenesis, 14(6), 489-93, June 1993 Abstract
  • Villacres E C, Xia Z, Bookbinder L H, Edelhoff S, Disteche C M, Storm D R, Cloning, chromosomal mapping, and expression of human fetal brain type I adenylyl cyclase, Genomics, 16(2), 473-8, May 1993 Abstract
  • Choi E J, Xia Z, Villacres E C, Storm D R, The regulatory diversity of the mammalian adenylyl cyclases, Current Opinion In Cell Biology, 5(2), 269-73, April 1993 Abstract
  • Choi E J, Wong S T, Dittman A H, Storm D R, Phorbol ester stimulation of the type I and type III adenylyl cyclases in whole cells, Biochemistry, 32(8), 1891-4, 2 Mar 1993 Abstract
  • Wu, Z., Wong, S. T., and Storm, D. R., Modification of the calcium and calmodulin sensitivity of the type I adenylyl cyclase by mutagenesis of its calmodulin binding domain, Journal of Biological Chemistry, 268, 23766-23768, 1993
  • Xia Z, Choi E J, Wang F, Blazynski C, Storm D R, Type I calmodulin-sensitive adenylyl cyclase is neural specific, Journal of Neurochemistry, 60(1), 305-11, January 1993 Abstract
  • Chapman E R, Alexander K, Vorherr T, Carafoli E, Storm D R, Fluorescence energy transfer analysis of calmodulin-peptide complexes, Biochemistry, 31(51), 12819-25, 29 Dec 1992 Abstract
  • Chapman E R, Estep R P, Storm D R, Palmitylation of neuromodulin (GAP-43) is not required for phosphorylation by protein kinase C, Journal of Biological Chemistry, 267(35), 25233-8, 15 Dec 1992 Abstract
  • Oldenburg D J, Gross M K, Wong C S, Storm D R, High-affinity calmodulin binding is required for the rapid entry of Bordetella pertussis adenylyl cyclase into neuroblastoma cells, Biochemistry, 31(37), 8884-91, 22 Sep 1992 Abstract
  • Xia Z, Choi E J, Wang F, Storm D R, The type III calcium/calmodulin-sensitive adenylyl cyclase is not specific to olfactory sensory neurons, Neuroscience Letters, 144(1-2), 169-73, 14 Sep 1992 Abstract
  • Choi E J, Xia Z, Storm D R, Stimulation of the type III olfactory adenylyl cyclase by calcium and calmodulin, Biochemistry, 31(28), 6492-8, 21 Jul 1992 Abstract
  • Choi E J, Wong S T, Hinds T R, Storm D R, Calcium and muscarinic agonist stimulation of type I adenylylcyclase in whole cells, Journal of Biological Chemistry, 267(18), 12440-2, 25 Jun 1992 Abstract
  • Gross M K, Au D C, Smith A L, Storm D R, Targeted mutations that ablate either the adenylate cyclase or hemolysin function of the bifunctional cyaA toxin of Bordetella pertussis abolish virulence, Proceedings of the National Academy of Sciences (USA), 89(11), 4898-902, 1 Jun 1992 Abstract
  • Apel E D, Storm D R, Functional domains of neuromodulin (GAP-43), Perspectives On Developmental Neurobiology, 1(1), 3-11, 1992 Abstract
  • Ross D T, Raibaud A, Florent I C, Sather S, Gross M K, Storm D R, Eisen H, The trypanosome VSG expression site encodes adenylate cyclase and a leucine-rich putative regulatory gene, Embo Journal, 10(8), 2047-53, August 1991 Abstract
  • Apel E D, Litchfield D W, Clark R H, Krebs E G, Storm D R, Phosphorylation of neuromodulin (GAP-43) by casein kinase II. Identification of phosphorylation sites and regulation by calmodulin, Journal of Biological Chemistry, 266(16), 10544-51, 5 Jun 1991 Abstract
  • Liu Y C, Storm D R, Expression of a neuromodulin-beta-galactosidase fusion protein in primary cultured neurons and its accumulation in growth cones, Molecular and Cellular Biochemistry, 104(1-2), 29-34, 29 May 1991 Abstract
  • Xia Z G, Refsdal C D, Merchant K M, Dorsa D M, Storm D R, Distribution of mRNA for the calmodulin-sensitive adenylate cyclase in rat brain: expression in areas associated with learning and memory, Neuron, 6(3), 431-43, March 1991 Abstract
  • Liu Y C, Chapman E R, Storm D R, Targeting of neuromodulin (GAP-43) fusion proteins to growth cones in cultured rat embryonic neurons, Neuron, 6(3), 411-20, March 1991 Abstract
  • Chapman E R, Au D, Alexander K A, Nicolson T A, Storm D R, Characterization of the calmodulin binding domain of neuromodulin. Functional significance of serine 41 and phenylalanine 42, Journal of Biological Chemistry, 266(1), 207-13, 5 Jan 1991 Abstract
  • Rosenberg G B, Wang P, Storm D R, Isolation of polyclonal antibodies against bovine brain calmodulin-sensitive adenylyl cyclases, Methods In Enzymology, 195, 110-21, 1991 Abstract
  • Wang P, Storm D R, Purification and characterization of calmodulin-sensitive adenylyl cyclase from bovine brain, Methods In Enzymology, 195, 65-82, 1991 Abstract
  • Chapman E R, Au D, Nicolson T A, Storm D R, Mutagenesis of the calmodulin binding domain of neuromodulin, Progress In Brain Research, 89, 37-44, 1991 Abstract
  • Masure H R, Donovan M G, Storm D R, Purification and assay of cell-invasive form of calmodulin-sensitive adenylyl cyclase from Bordetella pertussis, Methods In Enzymology, 195, 137-52, 1991 Abstract
  • Donovan M G, Storm D R, Evidence that the adenylate cyclase secreted from Bordetella pertussis does not enter animal cells by receptor-mediated endocytosis, Journal of Cellular Physiology, 145(3), 444-9, December 1990 Abstract
  • Deloulme J C, Janet T, Au D, Storm D R, Sensenbrenner M, Baudier J, Neuromodulin (GAP43): a neuronal protein kinase C substrate is also present in 0-2A glial cell lineage. Characterization of neuromodulin in secondary cultures of oligodendrocytes and comparison with t, Journal of Cell Biology, 111(4), 1559-69, October 1990 Abstract
  • Tota M R, Xia Z Q, Storm D R, Schimerlik M I, Reconstitution of muscarinic receptor-mediated inhibition of adenylyl cyclase, Molecular Pharmacology, 37(6), 950-7, June 1990 Abstract
  • Xia Z G, Storm D R, A-type ATP binding consensus sequences are critical for the catalytic activity of the calmodulin-sensitive adenylyl cyclase from Bacillus anthracis, Journal of Biological Chemistry, 265(12), 6517-20, 25 Apr 1990 Abstract
  • Apel E D, Byford M F, Au D, Walsh K A, Storm D R, Identification of the protein kinase C phosphorylation site in neuromodulin, Biochemistry, 29(9), 2330-5, 6 Mar 1990 Abstract
  • Liu Y C, Storm D R, Regulation of free calmodulin levels by neuromodulin: neuron growth and regeneration, Trends In Pharmacological Sciences, 11(3), 107-11, March 1990 Abstract
  • Masure H R, Au D C, Gross M K, Donovan M G, Storm D R, Secretion of the Bordetella pertussis adenylate cyclase from Escherichia coli containing the hemolysin operon, Biochemistry, 29(1), 140-5, 9 Jan 1990 Abstract
  • Estep R P, Alexander K A, Storm D R, Regulation of free calmodulin levels in neurons by neuromodulin: relationship to neuronal growth and regeneration, Current Topics In Cellular Regulation, 31, 161-80, 1990 Abstract
  • Au D C, Apel E D, Chapman E R, Estep R P, Nicolson T A, Storm D R, Expression of cDNAs encoding wild-type and mutant neuromodulins in Escherichia coli: comparison with the native protein from bovine brain, Biochemistry, 28(20), 8142-8, 3 Oct 1989 Abstract
  • Donovan M G, Masure H R, Storm D R, Isolation of a protein fraction from Bordetella pertussis that facilitates entry of the calmodulin-sensitive adenylate cyclase into animal cells, Biochemistry, 28(20), 8124-9, 3 Oct 1989 Abstract
  • Liu Y C, Storm D R, Dephosphorylation of neuromodulin by calcineurin, Journal of Biological Chemistry, 264(22), 12800-4, 5 Aug 1989 Abstract
  • Au D C, Masure H R, Storm D R, Site-directed mutagenesis of lysine 58 in a putative ATP-binding domain of the calmodulin-sensitive adenylate cyclase from Bordetella pertussis abolishes catalytic activity, Biochemistry, 28(7), 2772-6, 4 Apr 1989 Abstract
  • Masure H R, Storm D R, Characterization of the bacterial cell associated calmodulin-sensitive adenylate cyclase from Bordetella pertussis, Biochemistry, 28(2), 438-42, 24 Jan 1989 Abstract
  • Blumenthal DK, Charbonneau H, Edelman AM, Hinds TR, Rosenberg GB, Storm DR, Vincenzi FF, Beavo JA, Krebs EG, Synthetic peptides based on the calmodulin-binding domain of myosin light chain kinase inhibit activation of other calmodulin-dependent enzymes, Biochemical and Biophysical Research Communications, 156(2), 860-5, October 1988 Abstract
  • Alexander KA, Wakim BT, Doyle GS, Walsh KA, Storm DR, Identification and characterization of the calmodulin-binding domain of neuromodulin, a neurospecific calmodulin-binding protein, Journal of Biological Chemistry, 263(16), 7544-9, June 1988 Abstract
  • Masure HR, Oldenburg DJ, Donovan MG, Shattuck RL, Storm DR, The interaction of Ca2+ with the calmodulin-sensitive adenylate cyclase from Bordetella pertussis, Journal of Biological Chemistry, 263(14), 6933-40, May 1988 Abstract
  • Wakim BT, Alexander KA, Masure HR, Cimler BM, Storm DR, Walsh KA, Amino acid sequence of P-57, a neurospecific calmodulin-binding protein, Biochemistry, 26(23), 7466-70, November 1987 Abstract
  • Cimler BM, Giebelhaus DH, Wakim BT, Storm DR, Moon RT, Characterization of murine cDNAs encoding P-57, a neural-specific calmodulin-binding protein, Journal of Biological Chemistry, 262(25), 12158-63, September 1987 Abstract
  • Minocherhomjee M, Selfe S, Flowers NJ, Storm DR, Direct interaction between the catalytic subunit of the calmodulin-sensitive adenylate cyclase from bovine brain with 125I-labeled wheat germ agglutinin and 125I-labeled calmodulin, Biochemistry, 26(14), 4444-8, July 1987 Abstract
  • Rosenberg GB, Storm DR, Immunological distinction between calmodulin-sensitive and calmodulin-insensitive adenylate cyclases, Journal of Biological Chemistry, 262(16), 7623-8, June 1987 Abstract
  • Alexander KA, Cimler BM, Meier KE, Storm DR, Regulation of calmodulin binding to P-57. A neurospecific calmodulin binding protein, Journal of Biological Chemistry, 262(13), 6108-13, May 1987 Abstract
  • Selfe S, Hunter DD, Shattuck RL, Nathanson NM, Storm DR, Alteration of intracellular cAMP levels and beating rates of cultured chick cardiac cells by Bordetella pertussis adenylate cyclase, Molecular Pharmacology, 31(5), 529-34, May 1987 Abstract
  • Masure HR, Shattuck RL, Storm DR, Mechanisms of bacterial pathogenicity that involve production of calmodulin-sensitive adenylate cyclases, Microbiological Reviews, 51(1), 60-5, March 1987 Abstract
  • Rosenberg GB, Selfe S, Storm DR, Photoaffinity labeling of calmodulin-dependent systems, Pharmacology & Therapeutics, 32(2), 131-43, 1987 Abstract
  • Rosenberg GB, Minocherhomjee AM, Storm DR, Reconstitution of calmodulin-sensitive adenylate cyclase from bovine brain with phospholipids, calmodulin, and beta-adrenergic receptors, Methods in Enzymology, 139, 776-91, 1987 Abstract
  • Masure HR, Alexander KA, Wakim BT, Storm DR, Physicochemical and hydrodynamic characterization of P-57, a neurospecific calmodulin binding protein, Biochemistry, 25(23), 7553-60, November 1986 Abstract
  • Yeager RE, Nelson R, Storm DR, Adenosine inhibition of calmodulin-sensitive adenylate cyclase from bovine cerebral cortex, Journal of Neurochemistry, 47(1), 139-44, July 1986 Abstract
  • Olwin BB, Storm DR, Calcium binding to complexes of calmodulin and calmodulin binding proteins, Biochemistry, 24(27), 8081-6, December 1985 Abstract
  • Shattuck RL, Storm DR, Calmodulin inhibits entry of Bordetella pertussis adenylate cyclase into animal cells, Biochemistry, 24(23), 6323-8, November 1985 Abstract
  • Selfe S, Storm DR, Deacetylation of forskolin catalyzed by bovine brain membranes, Biochemical and Biophysical Research Communications, 133(1), 52-9, November 1985 Abstract
  • Shattuck RL, Oldenburg DJ, Storm DR, Purification and characterization of a calmodulin-sensitive adenylate cyclase from Bordetella pertussis, Biochemistry, 24(23), 6356-62, November 1985 Abstract
  • Cimler BM, Andreasen TJ, Andreasen KI, Storm DR, P-57 is a neural specific calmodulin-binding protein, Journal of Biological Chemistry, 260(19), 10784-8, September 1985 Abstract
  • Yeager RE, Heideman W, Rosenberg GB, Storm DR, Purification of the calmodulin-sensitive adenylate cyclase from bovine cerebral cortex, Biochemistry, 24(14), 3776-83, July 1985 Abstract
  • Yeager RE, Heideman W, Olwin BB, Keller CH, Schmidt JW, Shattuck RL, Storm DR, Reconstitution of calmodulin-sensitive adenylate cyclase from bovine brain with phosphatidylcholine liposomes, Journal of Neurochemistry, 44(3), 818-24, March 1985 Abstract
  • Olwin BB, Edelman AM, Krebs EG, Storm DR, Quantitation of energy coupling between Ca2+, calmodulin, skeletal muscle myosin light chain kinase, and kinase substrates, Journal of Biological Chemistry, 259(17), 10949-55, September 1984 Abstract
  • Olwin BB, Keller CH, Storm DR, Calcium-dependent and calcium-independent affinities of calmodulin for calmodulin-binding proteins determined by fluorescence techniques, Advances in Cyclic Nucleotide and Protein Phosphorylation Research, 16, 227-43, 1984 Abstract
  • Andreasen TJ, Luetje CW, Heideman W, Storm DR, Purification of a novel calmodulin binding protein from bovine cerebral cortex membranes, Biochemistry, 22(20), 4615-8, September 1983 Abstract
  • Garrity MJ, Andreasen TJ, Storm DR, Robertson RP, Prostaglandin E-induced heterologous desensitization of hepatic adenylate cyclase. Consequences on the guanyl nucleotide regulatory complex, Journal of Biological Chemistry, 258(14), 8692-7, July 1983 Abstract
  • Garrity MJ, Westcott KR, Eggerman TL, Andersen NH, Storm DR, Robertson RP, Interrelationships between PGE1 and PGI2 binding and stimulation of adenylate cyclase, The American Journal of Physiology, 244(4), E367-72, April 1983 Abstract
  • Olwin BB, Storm DR, Preparation of fluorescent labeled calmodulins, Methods in Enzymology, 102, 148-57, 1983 Abstract
  • Olwin BB, Keller CH, Storm DR, Interaction of a fluorescent N-dansylaziridine derivative of troponin I with calmodulin in the absence and presence of calcium, Biochemistry, 21(22), 5669-75, October 1982 Abstract
  • Greenlee DV, Andreasen TJ, Storm DR, Calcium-independent stimulation of Bordetella pertussis adenylate cyclase by calmodulin, Biochemistry, 21(11), 2759-64, May 1982 Abstract
  • Heideman W, Wierman BM, Storm DR, GTP is not required for calmodulin stimulation of bovine brain adenylate cyclase, 79(5), 1462-5, March 1982
  • Toscano WA Jr, Storm DR, Bacitracin, Pharmacology & Therapeutics, 16(2), 199-210, 1982 Abstract
  • Keller CH, Olwin BB, LaPorte DC, Storm DR, Determination of the free-energy coupling for binding of calcium ions and troponin I to calmodulin, Biochemistry, 21(1), 156-62, January 1982 Abstract
  • Rice MG, McRae JR, Storm DR, Robertson RP, Up-regulation of hepatic prostaglandin E receptors in vivo induced by prostaglandin synthesis inhibitors, The American Journal of Physiology, 241(4), E291-7, October 1981 Abstract
  • Eckstein F, Romaniuk PJ, Heideman W, Storm DR, Stereochemistry of the mammalian adenylate cyclase reaction, Journal of Biological Chemistry, 256(17), 9118-20, September 1981 Abstract
  • LaPorte DC, Keller CH, Olwin BB, Storm DR, Preparation of a fluorescent-labeled derivative of calmodulin which retains its affinity for calmodulin binding proteins, Biochemistry, 20(14), 3965-72, July 1981 Abstract
  • Andreasen TJ, Keller CH, LaPorte DC, Edelman AM, Storm DR, Preparation of azidocalmodulin: a photoaffinity label for calmodulin-binding proteins, 78(5), 2782-5, May 1981
  • Westcott KR, Olwin BB, Storm DR, Inhibition of adenylate cyclase by the 2',3'-dialdehyde of adenosine triphosphate, Journal of Biological Chemistry, 255(18), 8767-71, September 1980 Abstract
  • LaPorte DC, Wierman BM, Storm DR, Calcium-induced exposure of a hydrophobic surface on calmodulin, Biochemistry, 19(16), 3814-9, August 1980 Abstract
  • Robertson RP, Westcott KR, Storm DR, Rice MG, Down-regulation in vivo of PGE receptors and adenylate cyclase stimulation, The American Journal of Physiology, 239(1), E75-80, July 1980 Abstract
  • Scogin DA, Mosberg HI, Storm DR, Gennis RB, Binding of nickel and zinc ions to bacitracin A, Biochemistry, 19(14), 3348-52, July 1980 Abstract
  • Mosberg HI, Scogin DA, Storm DR, Gennis RB, Proton nuclear magnetic resonance studies on bacitracin A and its interaction with zinc ion, Biochemistry, 19(14), 3353-7, July 1980 Abstract
  • Swanson PE, Paddy MR, Dahlquist FW, Storm DR, Characterization of octapeptin-membrane interactions using spin-labeled octapeptin, Biochemistry, 19(14), 3307-14, July 1980 Abstract
  • LaPorte DC, Builder SE, Storm DR, Spectroscopic studies of the cAMP binding sites of the regulatory subunits of types I and II protein kinase, Journal of Biological Chemistry, 255(6), 2343-9, March 1980 Abstract
  • Gidwitz S, Pessin JE, Weber MJ, Glaser M, Storm DR, Effect of membrane phospholipid composition changes on adenylate cyclase activity in normal and rous-sarcoma-transformed chicken embryo fibroblasts, Biochimica Et Biophysica Acta, 628(3), 263-76, March 1980 Abstract
  • Gidwitz S, Toscano WA, Toscano DG, Weber MJ, Storm DR, A comparison between adenylate cyclase solubilized from normal and Rous sarcoma virus-transformed chicken embryo fibroblasts, Biochimica Et Biophysica Acta, 627(1), 1-16, January 1980 Abstract
  • Keller CH, LaPorte DC, Toscano WA Jr, Storm DR, Westcott KR, Ca2+ regulation of cyclic nucleotide metabolism, Annals of the New York Academy of Sciences, 356, 205-19, 1980 Abstract
  • Toscano WA Jr, Westcott KR, LaPorte DC, Storm DR, Evidence for a dissociable protein subunit required for calmodulin stimulation of brain adenylate cyclase, 76(11), 5582-6, November 1979
  • LaPorte DC, Toscano WA Jr, Storm DR, Cross-linking of iodine-125-labeled, calcium-dependent regulatory protein to the Ca2+-sensitive phosphodiesterase purified from bovine heart, Biochemistry, 18(13), 2820-5, June 1979 Abstract
  • Swanson PE, Storm DR, Inhibition of the respiratory-linked membrane potential in E. coli membrane vesicles by octapeptin, Journal of Antibiotics, 32(5), 511-7, May 1979 Abstract
  • Westcott KR, Engelhard VH, Storm DR, Production of cyclic AMP from extracellular ATP by intact LM cells, Biochimica Et Biophysica Acta, 583(1), 47-54, February 1979 Abstract
  • LaPorte DC, Gidwitz S, Weber MJ, Storm DR, Relationship between changes in the calcium dependent regulatory protein and adenylate cyclase during viral transformation, Biochemical and Biophysical Research Communications, 86(4), 1169-77, February 1979 Abstract
  • Westcott KR, La Porte DC, Storm DR, Resolution of adenylate cyclase sensitive and insensitive to Ca2+ and calcium-dependent regulatory protein (CDR) by CDR-sepharose affinity chromatography, 76(1), 204-8, January 1979
  • Engelhard VH, Storm DR, Glaser M, Negative cooperativity exhibited by prostaglandin E1 stimulated adenylate cyclase in LM cells, Biochemistry, 17(24), 5304-8, November 1978 Abstract
  • Engelhard VH, Glaser M, Storm DR, Effect of membrane phospholipid compositional changes on adenylate cyclase in LM cells, Biochemistry, 17(16), 3191-200, August 1978 Abstract
  • LaPorte DC, Storm DR, Detection of calcium-dependent regulatory protein binding components using 125I-labeled calcium-dependent regulatory protein, Journal of Biological Chemistry, 253(10), 3374-7, May 1978 Abstract
  • Rosenthal KS, Storm DR, Disruption of the Escherichia coli outer membrane permeability barrier by immobilized polymyxin B, Journal of Antibiotics, 30(12), 1087-92, December 1977 Abstract
  • Rosenthal KS, Ferguson RA, Storm DR, Mechanism of action of EM 49, membrane-active peptide antibiotic, Antimicrobial Agents and Chemotherapy, 12(6), 665-72, December 1977 Abstract
  • LaPorte DC, Rosenthal KS, Storm DR, Inhibition of Escherichia coli growth and respiration by polymyxin B covalently attached to agarose beads, Biochemistry, 16(8), 1642-8, April 1977 Abstract
  • Ryan J, Rogers GN, Toscano DG, Storm DR, Formation of adenosine 5'-phosphoroglycerol from ATP and glycerol by rat liver plasma membranes, Journal of Biological Chemistry, 252(5), 1719-22, March 1977 Abstract
  • Storm DR, Rosenthal KS, Swanson PE, Polymyxin and related peptide antibiotics, Annual Review of Biochemistry, 46, 723-63, 1977 Abstract
  • Gidwitz S, Weber MJ, Storm DR, Solubilization of adenylate cyclase from normal and Rous sarcoma-transformed chicken embryo fibroblasts, Journal of Biological Chemistry, 251(24), 7950-1, December 1976 Abstract
  • Rosenthal KS, Swanson PE, Storm DR, Disruption of Escherichia coli outer membranes by EM 49. A new membrane active peptide, Biochemistry, 15(26), 5783-92, December 1976 Abstract
  • Engelhard VH, Esko JD, Storm DR, Glaser M, Modification of adenylate cyclase activity in LM cells by manipulation of the membrane phospholipid composition in vivo, 73(12), 4482-6, December 1976
  • Engelhard VH, Plut DA, Storm DR, Subcellular location of adenylate cyclase in rat cardiac muscle, Biochimica Et Biophysica Acta, 451(1), 48-61, November 1976 Abstract
  • Storm DR, Field SO, Ryan J, The HLB dependency for detergent solubilization of hormonally sensitive adenylate cyclase, Journal of Supramolecular Structure, 4(2), 221-31, 1976 Abstract
  • Rosenthal KS, Storm DR, Ford WT, Triethyl-n-hexylammonium triethyl-n-hexylboride: a new antimicrobial showing activity against Candida albicans and gram-positive bacteria, Antimicrobial Agents and Chemotherapy, 8(4), 510-2, October 1975 Abstract
  • Storm DR, Chase RA, Exploitation of hormone-induced conformational changes to label selectively a component of rat liver plasma membranes, Journal of Biological Chemistry, 250(7), 2539-45, April 1975 Abstract
  • Ryan J, Storm DR, Solubilization of glucagon and epinephrine sensitive adenylate cyclase from rat liver plasma membranes, Biochemical and Biophysical Research Communications, 60(1), 304-11, September 1974 Abstract
  • Storm DR, Gunsalus RP, Methylmercury is a potent inhibitor of membrane adenyl cyclase, Nature, 250(5469), 778-9, August 1974 Abstract
  • Storm DR, Mechanism of bacitracin action: a specific lipid-peptide interaction, Annals of the New York Academy of Sciences, 235, 387-98, May 1974 Abstract
  • Storm DR, Blumberg PM, Strominger JL, Inhibition of the Bacillus subtilis membrane-bound D-alanine carboxypeptidase by 6-aminopenicillanic acid covalently coupled to sepharose, Journal of Bacteriology, 117(2), 783-5, February 1974 Abstract
  • Storm DR, Dolginow YD, Glucagon stimulation of adenylate cyclase sulfhydryl reactivity. Evidence for hormone-induced conformational changes, Journal of Biological Chemistry, 248(14), 5208-10, July 1973 Abstract
  • Storm DR, Strominger JL, Complex formation between bacitracin peptides and isoprenyl pyrophosphates. The specificity of lipid-peptide interactions, Journal of Biological Chemistry, 248(11), 3940-5, June 1973 Abstract
  • Koshland DE Jr, Carraway KW, Dafforn GA, Gass JD, Storm DR, The importance of orientation factors in enzymatic reactions, Cold Spring Harbor Symposia On Quantitative Biology, 36, 13-20, 1972 Abstract
  • Pocker Y, Storm DR, The catalytic versatility of erythrocyte carbonic anhydrase. IV. Kinetic studies of enzyme-catalyzed hydrolyses of para-nitrophenly esters, Biochemistry, 7(3), 1202-14, March 1968 Abstract
  • Lin, CH, Hansen, S, Wang, Z, Storm, DR, Tapscott, SJ and Olson, JM, The dosage of the neuroD2 transcription factor regulates amygdala development and emotional learning, Proc. Natl. Acad Sci. USA, In Press

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