William V. Tamborlane

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Yale University
School of Medicine
Yale Center for Clinical Investigation
Deputy DirectorAppointed: 2006
Yale University
School of Medicine
Pediatrics
Pediatric Endocrinology
Chief
Yale University
School of Medicine
Pediatrics
Pediatric Endocrinology
Professor
Professional Headshot of William V. Tamborlane

Mailing Address

333 Cedar Street
Yale University
3091 LMP
New Haven, Connecticut 06520
United States

Contact Information

Phone: (203) 785-4648
Fax: (203) 737-1998
william.tamborlane@yale.edu

Qualifications

M.D., Georgetown University, 1972.
B.S., Georgetown University, 1968.

Expertise and Research Interests

We have been employing sophisticated but relatively non invasive techniques including insulin and glucose clamps, microdialysis techniques, stable isotope infusions, indirect calorimetry, magnetic resonance spectroscopy and vascular reactivity in studies in healthy children and adults, in patients with type 1 diabetes, and in obese children with and with out diabetes.

For more than 25 years, the focus of our work has been to advance the treatment of type 1 diabetes through patient-oriented research. Major accomplishments have included pioneering studies in the development of insulin-pump therapy, direction of Yale Center in the DCCT/EDIC study, investigations of diabetes-induced defects in counter-regulatory hormone responses to hypoglycemia, and demonstration of the role of insulin resistance in pediatric metabolic disorders. Current research effort is directed at applying recent advances in insulin pump and glucose sensor technology towards the development of an artificial pancreas. Dr. Tamborlane has been Steering Committee Chair of the Diabetes Research in Children's Network (DirecNet), a NIH multicenter group that is testing glucose sensing systems in children that includes Yale and is now Co-Steering Committee Chair of the JDRF Senosr Network. He received the 2006 JDRF Award for excellence in clinical research in diabetes. Studies in type 1 diabetes are facilitated by our multidisciplinary team of physicians, diabetes nurse educators, dieticians and social workers that care for more than 1000 children, adolescents and young adults with diabetes.

We are also studying the metabolic and clinical consequences of childhood obesity, including studies of the development of altered glucose metabolism and the metabolic syndrome in obese youth. We are one of the centers in the NIH-sponsored studies of treatment of adolescents with type 2 diabetes and are carrying out our own studies of interventions aimed at preventing the developing type 2 diabetes in overweight adolescents.

Other Expertise

Academic Experience:
I wish to be contacted by interested students (medical, graduate or undergraduates) as a potential research mentor/thesis advisor.

Future Research

The development and testing of closed-loop insulin delivery systems for type 1 diabetes.

Industrial Relevance

Very knowledgeable regarding new therapies and technologies for T2DM as well as T1DM.

Keywords

COS Keywords:

Clinical Trial, Diabetes, Electrophysiology, Endocrinology, Growth Factors, Growth Hormone, Magnetic Resonance, Metabolism, Obesity, Pediatrics, Puberty, Resonance Spectroscopy.

Additional Terms:

Clinical Investigation, Growth Factors, Hypoglycemia, Metabolic Syndrome, Metabolism, Obesity, Phase 1-4 Studies in Children, Puberty, Type 1 Diabetes Mellitus, Type 2 Diabetes.

Memberships

American Academy of Pediatrics
American Diabetes Association
American Pediatric Society
American Society for Clinical Investigation
Lawson Wilkins Pediatric Endocrine Society
Society for Pediatric Research

Previous Positions

Fellow, Yale University

Publications

  • Mauras N, Beck RW, Ruedy KJ, Kollman C, Tamborlane WV, Chase HP, Buckingham BA, Tsalikian E, Weinzimer S, Booth AD, Xing D, Diabetes Research in Children Network (DirecNet) Accuracy Study, Lack of accuracy of continuous glucose sensors in healthy, nondiabetic children: results of the Diabetes Research in Children Network (DirecNet) accuracy study, The Journal of Pediatrics, 144(6), 770-5, June 2004 Abstract
  • Weiss R, Dziura J, Burgert TS, Tamborlane WV, Taksali SE, Yeckel CW, Allen K, Lopes M, Savoye M, Morrison J, Sherwin RS, Caprio S, Obesity and the metabolic syndrome in children and adolescents, The New England Journal of Medicine, 350(23), 2362-74, June 2004 Abstract
  • Weinzimer SA, Tamborlane WV, Chase HP, Garg SK, Continuous glucose monitoring in type 1 diabetes, Current Diabetes Reports, 4(2), 95-100, April 2004 Abstract
  • Yeckel CW, Weiss R, Dziura J, Taksali SE, Dufour S, Burgert TS, Tamborlane WV, Caprio S, Validation of insulin sensitivity indices from oral glucose tolerance test parameters in obese children and adolescents, Journal of Clinical Endocrinology and Metabolism, 89(3), 1096-101, March 2004 Abstract
  • Whittemore R, Urban AD, Tamborlane WV, Grey M, Quality of life in school-aged children with type 1 diabetes on intensive treatment and their parents, The Diabetes Educator, 29(5), 847-54, 2003 Abstract
  • Weiss R, Dufour S, Taksali SE, Tamborlane WV, Petersen KF, Bonadonna RC, Boselli L, Barbetta G, Allen K, Rife F, Savoye M, Dziura J, Sherwin R, Shulman GI, Caprio S, Prediabetes in obese youth: a syndrome of impaired glucose tolerance, severe insulin resistance, and altered myocellular and abdominal fat partitioning, Lancet, 362(9388), 951-7, September 2003 Abstract
  • Heptulla RA, Stewart A, Enocksson S, Rife F, Ma TY, Sherwin RS, Tamborlane WV, Caprio S, In situ evidence that peripheral insulin resistance in adolescents with poorly controlled type 1 diabetes is associated with impaired suppression of lipolysis: a microdialysis study, Pediatric Research, 53(5), 830-5, May 2003 Abstract
  • Enoksson S, Caprio SK, Rife F, Shulman GI, Tamborlane WV, Sherwin RS, Defective activation of skeletal muscle and adipose tissue lipolysis in type 1 diabetes mellitus during hypoglycemia, Journal of Clinical Endocrinology and Metabolism, 88(4), 1503-11, April 2003 Abstract
  • Borg MA, Tamborlane WV, Shulman GI, Sherwin RS, Local lactate perfusion of the ventromedial hypothalamus suppresses hypoglycemic counterregulation, Diabetes, 52(3), 663-6, March 2003 Abstract
  • Sullivan-Bolyai S, Deatrick J, Gruppuso P, Tamborlane W, Grey M, Constant vigilance: mothers' work parenting young children with type 1 diabetes, Journal of Pediatric Nursing, 18(1), 21-9, February 2003 Abstract
  • Flanagan DE, Evans ML, Monsod TP, Rife F, Heptulla RA, Tamborlane WV, Sherwin RS, The influence of insulin on circulating ghrelin, American Journal of Physiology. Endocrinology and Metabolism, 284(2), E313-6, February 2003 Abstract
  • Weinzimer SA, DeLucia MC, Boland EA, Steffen A, Tamborlane WV, Analysis of continuous glucose monitoring data from non-diabetic and diabetic children: a tale of two algorithms, Diabetes Technology & Therapeutics, 5(3), 375-80, 2003 Abstract
  • Tamborlane WV, Boland EA, Ahern JH, Insulin pump therapy in children and adolescents, Diabetes, Nutrition & Metabolism, 15(6), 422-5, December 2002 Abstract
  • Grey M, Whittemore R, Tamborlane W, Depression in type 1 diabetes in children: natural history and correlates, Journal of Psychosomatic Research, 53(4), 907-11, October 2002 Abstract
  • Sullivan-Bolyai S, Deatrick J, Gruppuso P, Tamborlane W, Grey M, Mothers' experiences raising young children with type 1 diabetes, Journal for Specialists in Pediatric Nursing : Jspn, 7(3), 93-103, 2002 Abstract
  • Savoye M, Dziura J, Castle J, DiPietro L, Tamborlane WV, Caprio S, Importance of plasma leptin in predicting future weight gain in obese children: a two-and-a-half-year longitudinal study, International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity., 26(7), 942-6, July 2002 Abstract
  • Bode BW, Tamborlane WV, Davidson PC, Insulin pump therapy in the 21st century. Strategies for successful use in adults, adolescents, and children with diabetes, Postgraduate Medicine, 111(5), 69-77; quiz 27, May 2002 Abstract
  • Monsod TP, Flanagan DE, Rife F, Saenz R, Caprio S, Sherwin RS, Tamborlane WV, Do sensor glucose levels accurately predict plasma glucose concentrations during hypoglycemia and hyperinsulinemia?, Diabetes Care, 25(5), 889-93, May 2002 Abstract
  • White NH, Cleary PA, Dahms W, Goldstein D, Malone J, Tamborlane WV, Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes, Beneficial effects of intensive therapy of diabetes during adolescence: outcomes after the conclusion of the Diabetes Control and Complications Trial (DCCT), The Journal of Pediatrics, 139(6), 804-12, December 2001
  • Tamborlane WV, Bonfig W, Boland E, Recent advances in treatment of youth with Type 1 diabetes: better care through technology, Diabetic Medicine : a Journal of the British Diabetic Association, 18(11), 864-70, November 2001 Abstract
  • Boland E, Monsod T, Delucia M, Brandt CA, Fernando S, Tamborlane WV, Limitations of conventional methods of self-monitoring of blood glucose: lessons learned from 3 days of continuous glucose sensing in pediatric patients with type 1 diabetes, Diabetes Care, 24(11), 1858-62, November 2001 Abstract
  • Raskin P, Holcombe JH, Tamborlane WV, Malone JI, Strowig S, Ahern JA, Lavent F, A comparison of insulin lispro and buffered regular human insulin administered via continuous subcutaneous insulin infusion pump, Journal of Diabetes and Its Complications, 15(6), 295-300, 2001 Abstract
  • Russell RR 3rd, Chyun D, Song S, Sherwin RS, Tamborlane WV, Lee FA, Pfeifer MA, Rife F, Wackers FJ, Young LH, Cardiac responses to insulin-induced hypoglycemia in nondiabetic and intensively treated type 1 diabetic patients, American Journal of Physiology. Endocrinology and Metabolism, 281(5), E1029-36, November 2001 Abstract
  • Grey M, Davidson M, Boland EA, Tamborlane WV, Clinical and psychosocial factors associated with achievement of treatment goals in adolescents with diabetes mellitus, The Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine, 28(5), 377-85, May 2001 Abstract
  • Monsod TP, Tamborlane WV, Coraluzzi L, Bronson M, Yong-Zhan T, Ahern JA, Epipen as an alternative to glucagon in the treatment of hypoglycemia in children with diabetes, Diabetes Care, 24(4), 701-4, April 2001 Abstract
  • Heptulla RA, Tamborlane WV, Ma TY, Rife F, Sherwin RS, Oral glucose augments the counterregulatory hormone response during insulin-induced hypoglycemia in humans, Journal of Clinical Endocrinology and Metabolism, 86(2), 645-8, February 2001 Abstract
  • Griffin ME, Feder A, Tamborlane WV, Lipoatrophy associated with lispro insulin in insulin pump therapy: an old complication, a new cause?, Diabetes Care, 24(1), 174, Jan 2001 Abstract
  • Heptulla R, Smitten A, Teague B, Tamborlane WV, Ma YZ, Caprio S, Temporal patterns of circulating leptin levels in lean and obese adolescents: relationships to insulin, growth hormone, and free fatty acids rhythmicity, Journal of Clinical Endocrinology and Metabolism, 86(1), 90-6, Jan 2001 Abstract
  • Enoksson S, Talbot M, Rife F, Tamborlane WV, Sherwin RS, Caprio S, Impaired in vivo stimulation of lipolysis in adipose tissue by selective beta2-adrenergic agonist in obese adolescent girls, Diabetes, 49(12), 2149-53, December 2000 Abstract
  • Ahern JA, Ramchandani N, Cooper J, Himmel A, Silver D, Tamborlane WV, Using a primary nurse manager to implement DCCT recommendations in a large pediatric program, The Diabetes Educator, 26(6), 990-4, 2000 Abstract
  • Grey M, Boland EA, Davidson M, Li J, Tamborlane WV, Coping skills training for youth with diabetes mellitus has long-lasting effects on metabolic control and quality of life, The Journal of Pediatrics, 137(1), 107-13, July 2000 Abstract
  • Ramchandani N, Cantey-Kiser JM, Alter CA, Brink SJ, Yeager SD, Tamborlane WV, Chipkin SR, Self-reported factors that affect glycemic control in college students with type 1 diabetes, The Diabetes Educator, 26(4), 656-66, 2000 Abstract
  • Rosenbloom AL, Schatz DA, Krischer JP, Skyler JS, Becker DJ, Laporte RE, Libman I, Pietropaolo M, Dosch HM, Finberg L, Muir A, Tamborlane WV, Grey M, Silverstein JH, Malone JI, Therapeutic controversy: prevention and treatment of diabetes in children, Journal of Clinical Endocrinology and Metabolism, 85(2), 494-522, February 2000 Abstract
  • Grey M, Boland EA, Davidson M, Yu C, Tamborlane WV, Coping skills training for youths with diabetes on intensive therapy., Applied Nursing Research, 12(1), 3-12, February 1999 Abstract
  • Boland EA, Grey M, Mezger J, Tamborlane WV, A summer vacation from diabetes: evidence from a clinical trial., Diabetes Educator, 25(1), 31-40, Jan 1999 Abstract
  • Jones T W, Porter P, Sherwin R S, Davis E A, O'Leary P, Frazer F, Byrne G, Stick S, Tamborlane W V, Decreased epinephrine responses to hypoglycemia during sleep., New England Journal of Medicine, 338(23), 1657-62, 4 Jun 1998 Abstract
  • Grey M, Boland E A, Yu C, Sullivan-Bolyai S, Tamborlane W V, Personal and family factors associated with quality of life in adolescents with diabetes [see comments], Diabetes Care, 21(6), 909-14, June 1998 Abstract
  • Grey M, Boland E A, Davidson M, Yu C, Sullivan-Bolyai S, Tamborlane W V, Short-term effects of coping skills training as adjunct to intensive therapy in adolescents [see comments], Diabetes Care, 21(6), 902-8, June 1998 Abstract
  • Attia N, Jones T W, Holcombe J, Tamborlane W V, Comparison of human regular and lispro insulins after interruption of continuous subcutaneous insulin infusion and in the treatment of acutely decompensated IDDM., Diabetes Care, 21(5), 817-21, May 1998 Abstract
  • Attia N, Tamborlane W V, Heptulla R, Maggs D, Grozman A, Sherwin R S, Caprio S, The metabolic syndrome and insulin-like growth factor I regulation in adolescent obesity., Journal of Clinical Endocrinology and Metabolism, 83(5), 1467-71, May 1998 Abstract
  • Robinson C, Tamborlane W V, Maggs D G, Enoksson S, Sherwin R S, Silver D, Shulman G I, Caprio S, Effect of insulin on glycerol production in obese adolescents., American Journal of Physiology, 274(4 Pt 1), E737-43, April 1998 Abstract
  • Attia N, Zahrani A, Saif R, Kattan H A, Sakati N, Al Ashwal A, Tamborlane W V, Different faces of non-autoimmune diabetes of infancy., Acta Paediatrica, 87(1), 95-7, Jan 1998 Abstract
  • Heptulla R A, Boulware S D, Caprio S, Silver D, Sherwin R S, Tamborlane W V, Decreased insulin sensitivity and compensatory hyperinsulinemia after hormone treatment in children with short stature., Journal of Clinical Endocrinology and Metabolism, 82(10), 3234-8, October 1997 Abstract
  • Jones T W, Borg W P, Borg M A, Boulware S D, McCarthy G, Silver D, Tamborlane W V, Sherwin R S, Resistance to neuroglycopenia: an adaptive response during intensive insulin treatment of diabetes., Journal of Clinical Endocrinology and Metabolism, 82(6), 1713-8, June 1997 Abstract
  • Tamborlane W V, Ahern J, Implications and results of the Diabetes Control and Complications Trial., Pediatric Clinics of North America, 44(2), 285-300, April 1997 Abstract
  • Limb C, Tamborlane W V, Sherwin R S, Pederson R, Caprio S, Acute incretin response to oral glucose is associated with stimulation of gastric inhibitory polypeptide, not glucagon-like peptide in young subjects., Pediatric Research, 41(3), 364-7, March 1997 Abstract
  • Borg M A, Sherwin R S, Borg W P, Tamborlane W V, Shulman G I, Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats., Journal of Clinical Investigation, 99(2), 361-5, 15 Jan 1997 Abstract
  • Tamborlane W V, Ahern J, Insulin-dependent diabetes in children., Current Therapy In Endocrinology and Metabolism, 6, 413-8, 1997 Abstract
  • Maggs D G, Jacob R, Rife F, Caprio S, Tamborlane W V, Sherwin R S, Counterregulation in peripheral tissues: effect of systemic hypoglycemia on levels of substrates and catecholamines in human skeletal muscle and adipose tissue., Diabetes, 46(1), 70-6, January 1997 Abstract
  • Caprio S, Bronson M, Sherwin R S, Rife F, Tamborlane W V, Co-existence of severe insulin resistance and hyperinsulinaemia in pre-adolescent obese children., Diabetologia, 39(12), 1489-97, December 1996 Abstract
  • Caprio S, Tamborlane W V, Silver D, Robinson C, Leibel R, McCarthy S, Grozman A, Belous A, Maggs D, Sherwin R S, Hyperleptinemia: an early sign of juvenile obesity. Relations to body fat depots and insulin concentrations., American Journal of Physiology, 271(3 Pt 1), E626-30, September 1996 Abstract
  • Caprio S, Hyman L D, McCarthy S, Lange R, Bronson M, Tamborlane W V, Fat distribution and cardiovascular risk factors in obese adolescent girls: importance of the intraabdominal fat depot., American Journal of Clinical Nutrition, 64(1), 12-7, July 1996 Abstract
  • Raskin G S, Tamborlane W V, Molecular and physiological aspects of nephropathy in type I (insulin-dependent) diabetes mellitus., Journal of Diabetes and Its Complications, 10(1), 31-7, January 1996 Abstract
  • Girardi N L, Shaywitz S E, Shaywitz B A, Marchione K, Fleischman S J, Jones T W, Tamborlane W V, Blunted catecholamine responses after glucose ingestion in children with attention deficit disorder., Pediatric Research, 38(4), 539-42, October 1995 Abstract
  • Maggs D G, Jacob R, Rife F, Lange R, Leone P, During M J, Tamborlane W V, Sherwin R S, Interstitial fluid concentrations of glycerol, glucose, and amino acids in human quadricep muscle and adipose tissue. Evidence for significant lipolysis in skeletal muscle., Journal of Clinical Investigation, 96(1), 370-7, July 1995 Abstract
  • Caprio S, Hyman L D, Limb C, McCarthy S, Lange R, Sherwin R S, Shulman G, Tamborlane W V, Central adiposity and its metabolic correlates in obese adolescent girls., American Journal of Physiology, 269(1 Pt 1), E118-26, July 1995 Abstract
  • Jones T W, Borg W P, Boulware S D, McCarthy G, Sherwin R S, Tamborlane W V, Enhanced adrenomedullary response and increased susceptibility to neuroglycopenia: mechanisms underlying the adverse effects of sugar ingestion in healthy children., Journal of Pediatrics, 126(2), 171-7, February 1995 Abstract
  • Reece E A, Hagay Z, Roberts A B, DeGennaro N, Homko C J, Connolly-Diamond M, Sherwin R, Tamborlane W V, Diamond M P, Fetal Doppler and behavioral responses during hypoglycemia induced with the insulin clamp technique in pregnant diabetic women., American Journal of Obstetrics and Gynecology, 172(1 Pt 1), 151-5, January 1995 Abstract
  • Caprio S, Cline G, Boulware S, Permanente C, Shulman G I, Sherwin R S, Tamborlane W V, Effects of puberty and diabetes on metabolism of insulin-sensitive fuels., American Journal of Physiology, 266(6 Pt 1), E885-91, June 1994 Abstract
  • Boulware S D, Tamborlane W V, Rennert N J, Gesundheit N, Sherwin R S, Comparison of the metabolic effects of recombinant human insulin-like growth factor-I and insulin. Dose-response relationships in healthy young and middle-aged adults., Journal of Clinical Investigation, 93(3), 1131-9, March 1994 Abstract
  • Diamond M P, Jones T, Caprio S, Hallarman L, Diamond M C, Addabbo M, Tamborlane W V, Sherwin R S, Gender influences counterregulatory hormone responses to hypoglycemia., Metabolism: Clinical and Experimental, 42(12), 1568-72, December 1993 Abstract
  • Ahern J, Grove N, Strand T, Wesche J, Seibert C, Brenneman A T, Tamborlane W V, The impact of the Trial Coordinator in the Diabetes Control and Complications Trial (DCCT). The DCCT Research Group., Diabetes Educator, 19(6), 509-12, November 1993 Abstract
  • Kerr D, Sherwin R S, Pavalkis F, Fayad P B, Sikorski L, Rife F, Tamborlane W V, During M J, Effect of caffeine on the recognition of and responses to hypoglycemia in humans., Annals of Internal Medicine, 119(8), 799-804, 15 Oct 1993 Abstract
  • Kerr D, Diamond M P, Tamborlane W V, Kerr S, Sherwin R S, Influence of counterregulatory hormones, independently of hypoglycaemia, on cognitive function, warning symptoms and glucose kinetics., Clinical Science, 85(2), 197-202, August 1993 Abstract
  • Jones T W, Boulware S D, Caprio S, Merkel P, Amiel S A, Pearson H A, Sherwin R S, Tamborlane W V, Correction of hyperinsulinemia by glyburide treatment in nondiabetic patients with thalassemia major., Pediatric Research, 33(5), 497-500, May 1993 Abstract
  • Caprio S, Tamborlane W V, Zych K, Gerow K, Sherwin R S, Loss of potentiating effect of hypoglycemia on the glucagon response to hyperaminoacidemia in IDDM., Diabetes, 42(4), 550-5, April 1993 Abstract
  • Ahern J A, Gatcomb P M, Held N A, Petit W A Jr, Tamborlane W V, Exaggerated hyperglycemia after a pizza meal in well-controlled diabetes [see comments], Diabetes Care, 16(4), 578-80, April 1993 Abstract
  • Rennert N J, Boulware S D, Kerr D, Caprio S, Tamborlane W V, Sherwin R S, Metabolic effects of rhIGF-1 in normal human subjects., Advances In Experimental Medicine and Biology, 343, 311-8, 1993 Abstract
  • Kerr D, Tamborlane W V, Rife F, Sherwin R S, Effect of insulin-like growth factor-1 on the responses to and recognition of hypoglycemia in humans. A comparison with insulin., Journal of Clinical Investigation, 91(1), 141-7, January 1993 Abstract
  • Gruetter R, Novotny E J, Boulware S D, Rothman D L, Mason G F, Shulman G I, Tamborlane W V, Shulman R G, Non-invasive measurements of the cerebral steady-state glucose concentration and transport in humans by 13C nuclear magnetic resonance., Advances In Experimental Medicine and Biology, 331, 35-40, 1993 Abstract
  • Caprio S, Amiel S A, Merkel P, Tamborlane W V, Insulin-resistant syndromes in children., Hormone Research, 39 Suppl 3, 112-4, 1993 Abstract
  • Caprio S, Napoli R, Sacca L, Tamborlane W V, Sherwin R S, Impaired stimulation of gluconeogenesis during prolonged hypoglycemia in intensively treated insulin-dependent diabetic subjects., Journal of Clinical Endocrinology and Metabolism, 75(4), 1076-80, October 1992 Abstract
  • Tamborlane W V, Semantics of plasma glucose thresholds for counterregulatory responses [letter], Diabetes Care, 15(10), 1434-5, October 1992 Abstract
  • Tamborlane W V, Amiel S A, Hypoglycemia in the treated diabetic patient. A risk of intensive insulin therapy., Endocrinology and Metabolism Clinics of North America, 21(2), 313-27, June 1992 Abstract
  • Boulware S D, Tamborlane W V, Not all severe hyperglycemia is diabetes., Pediatrics, 89(2), 330-2, February 1992 Abstract
  • Caprio S, Boulware S D, Press M, Sherwin R S, Rubin K, Carpenter T O, Plewe G, Tamborlane W V, Effect of growth hormone treatment on hyperinsulinemia associated with Turner syndrome., Journal of Pediatrics, 120(2 Pt 1), 238-43, February 1992 Abstract
  • Gruetter R, Novotny E J, Boulware S D, Rothman D L, Mason G F, Shulman G I, Shulman R G, Tamborlane W V, Direct measurement of brain glucose concentrations in humans by 13C NMR spectroscopy [published erratum appears in Proc Natl Acad Sci U S A 1992 Dec 15;89(24):12208], Proceedings of the National Academy of Sciences (USA), 89(3), 1109-12, 1 Feb 1992 Abstract
  • Press M, Caprio S, Tamborlane W V, Bhushan R, Thorner M, Vale W, Rivier J, Sherwin R S, Pituitary response to growth hormone-releasing hormone in IDDM. Abnormal responses to insulin and hyperglycemia., Diabetes, 41(1), 17-21, January 1992 Abstract
  • Diamond M P, Reece E A, Caprio S, Jones T W, Amiel S, DeGennaro N, Laudano A, Addabbo M, Sherwin R S, Tamborlane W V, Impairment of counterregulatory hormone responses to hypoglycemia in pregnant women with insulin-dependent diabetes mellitus., American Journal of Obstetrics and Gynecology, 166(1 Pt 1), 70-7, January 1992 Abstract
  • Boulware S D, Tamborlane W V, Matthews L S, Sherwin R S, Diverse effects of insulin-like growth factor I on glucose, lipid, and amino acid metabolism., American Journal of Physiology, 262(1 Pt 1), E130-3, January 1992 Abstract
  • Jones T W, Caprio S, Diamond M P, Hallarman L, Boulware S D, Sherwin R S, Tamborlane W V, Does insulin species modify counterregulatory hormone response to hypoglycemia?, Diabetes Care, 14(8), 728-31, August 1991 Abstract
  • Reece E A, Coustan D R, Sherwin R S, Tuck S, Bates S, O'Connor T, Tamborlane W V, Does intensive glycemic control in diabetic pregnancies result in normalization of other metabolic fuels?, American Journal of Obstetrics and Gynecology, 165(1), 126-30, July 1991 Abstract
  • Diamond M P, Hallarman L, Starick-Zych K, Jones T W, Connolly-Howard M, Tamborlane W V, Sherwin R S, Suppression of counterregulatory hormone response to hypoglycemia by insulin per se., Journal of Clinical Endocrinology and Metabolism, 72(6), 1388-90, June 1991 Abstract
  • Caprio S, Gerety G, Tamborlane W V, Jones T, Diamond M, Jacob R, Sherwin R S, Opiate blockade enhances hypoglycemic counterregulation in normal and insulin-dependent diabetic subjects., American Journal of Physiology, 260(6 Pt 1), E852-8, June 1991 Abstract
  • Caprio S, Boulware S, Diamond M, Sherwin R S, Carpenter T O, Rubin K, Amiel S, Press M, Tamborlane W V, Insulin resistance: an early metabolic defect of Turner's syndrome., Journal of Clinical Endocrinology and Metabolism, 72(4), 832-6, April 1991 Abstract

Profile Details

Last Updated: 8/9/2007

COS Expertise ID #397302
Reference this profile directly: http://myprofile.cos.com/tamborlw02