Dr. Nicole Urban

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Fred Hutchinson Cancer Research Center
Public Health Sciences Division
Molecular Diagnostics Program
Associate HeadAppointed: 2006
Fred Hutchinson Cancer Research Center
Women's Cancer Research Program
Co-Program HeadAppointed: 2008
Fred Hutchinson Cancer Research Center
Public Health Sciences Division
Solid Tumor Affinity Group
HeadAppointed: 2008
University of Washington
School of Public Health and Community Medicine
Department of Health Sciences
Research ProfessorAppointed: 2000
Professional Headshot of Nicole Urban

Mailing Address

Molecular Diagnostics Program
Fred Hutchinson Cancer Research Center
1100 Fairview Ave N
M2-B230
Seattle, Washington 98109
United States

Contact Information

Phone: (206) 667-4677
Fax: (206) 667-7264
nurban@fhcrc.org

Qualifications

Sc.D., 1978.
M.S., 1973.

Expertise and Research Interests

Ovarian cancer
Breast cancer
Cancer screening
Biomarkers
Cost-effectiveness analysis
Diagnostic imaging
Health economics

Dr. Urban heads the Translational and Outcomes Research (TOR) group at Fred Hutchinson Cancer Research Center. TOR spans the process of discovery, development, and evaluation of targets and interventions to improve outcomes for individuals at risk for cancer. The translational component involves working closely with clinical as well as laboratory researchers, and with patients as well as with healthy individuals. It involves comparative genomics and proteomics and the development of statistical methods to analyze gene expression and biomarker data. Our emphasis is on early detection and immunotherapy for prevention of cancer and/or recurrence of cancer, particularly ovarian and breast cancer. The outcomes component emphasizes modeling and cost-effectiveness analysis, including mathematical modeling of disease progression, modeling of the behavior of biomarkers in the absence and presence of cancer, and measurement and analysis of costs and quality-of-life. The work of TOR investigators includes interventions for current patients, both preventing recurrence (for example, vaccines to prevent recurrence of ovarian cancer) and improving quality of life in cancer survivors. It includes intervention trials, both randomized and Phase I.

Dr. Urban is also the Co-Program Head of the Women's Cancer Research Program (WCRP) at the Fred Hutchinson Cancer Research Center. The WCRP focuses on improving clinical outcomes in patients with reproductive malignancies at every stage of disease. The themes of the program are (1) developing novel treatments based on identification of genetic alterations involved in the malignant transformation, (2) prevention of relapse and eventually primary disease using immunotherapeutic strategies, and (3) early detection of disease.

In September 1999, Dr. Urban and colleagues at several West Coast collaborating research institutions were awarded an NCI Specialized Program of Research Excellence (SPORE) grant in ovarian cancer, which was renewed in July, 2004. The "Pacific Ovarian Cancer Research Consortium/SPORE in Ovarian Cancer" is a community-based, multidisciplinary, translational research program that involves clinicians, laboratory scientists and public health scientists. Its broad based approach takes full advantage of the scientific expertise available locally and allows the pooling of clinical resources, thus facilitating population-based studies despite the low incidence of ovarian cancer. POCRC research projects include: discovering genes that influence the responsiveness of ovarian cancer to chemotherapy treatments, creating an ovarian cancer vaccine that would attack ovarian cancer cells as soon as they develop, developing a statistical model that can estimate a woman's risk for developing ovarian cancer, and refining and improving the use of blood tests used to detect ovarian cancer. The POCRC also includes a Developmental Research Program and a Career Development Program. The group has established a well-characterized ovarian specimen repository housing over 200,000 individually identified specimens, and shared their findings with the broader research community through numerous presentations and publications.

In 2002, Dr. Urban was awarded by the DOD a "Center for the Evaluation of Biomarkers for the Early Detection of Breast Cancer." Investigators from 10 institutions are working together to evaluate breast cancer biomarkers for their contribution to the early detection of breast cancer. The study's goal is to define a biomarker panel that can be used in conjunction with current screening methods to improve early detection of all breast cancers, particularly aggressive cancers and those missed by mammography. Blood and tissue specimens for biomarker analysis are collected from women having annual mammograms and breast-related biopsies or surgery. This study utilizes the ongoing Mammography Tumor Registry for Breast Cancer Research to follow participants throughout the study and monitor their mammography data and breast cancer outcomes.

Her R01 awarded in 2002, "Modeling Ovarian Cancer Screening for CEA," allowed her to improve the accuracy of a previously developed microsimulation model of ovarian cancer screening by accounting for heterogeneity in the disease and in the population screened, in order to evaluate the cost-effectiveness of using a marker panel longitudinally to detect developing disease. The model now accommodates use of (1) a panel of serum markers for screening and (2) risk-based screening, incorporates QOL effects of both screening and disease, and incorporates updated screening and treatment costs. These efforts enable us to identify the potentially most efficient strategies for ovarian cancer screening and to report their cost-effectiveness.

Keywords

COS Keywords:

Biomarkers, Breast Cancer, Cancer Biology, Cancer Or Carcinogenesis, Health Care Economics, Ovarian Cancer.

Additional Terms:

Biomarkers, Breast Cancer, Cancer Biology, Cancer Screening, Cost-effective Analysis, Heath Economics, Mammography, Ovarian Cancer.

Memberships

American Public Health Association
American Society of Preventive Oncology
Association for Health Services Research
Society for Clinical Trials
Southwest Oncology Group

Previous Positions

2001-2008, Program Head, Fred Hutchinson Cancer Research Center, Gynecological Cancer Research Program
1998-2005, Member, Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Cancer Prevention Research Program
1996-2005, Scientific Director, Marsha Rivkin Center for Ovarian Cancer Research

Funding Received

  • National Institutes of Health/National Cancer Institute: 'Validation of a Biomarker Panel for Early Detection of Breast Cancer in High-Risk Women', 2003 to 2004.
  • Department of Defense/U.S. Army: 'Center for the Evaluation of Biomarkers for the Early Detection of Breast Cancer', $1,114,579, 2002 to 2006.
  • National Institutes of Health/National Cancer Institute: 'Modeling Ovarian Cancer Screening for CEA', $166,250, 2002 to 2006.
  • National Institutes of Health (NIH): 'Pacific Ovarian Cancer Research Consortium' (SPORE in Ovarian Cancer), $1,727,230, 1999 to 2004.
  • Department of Defense/U.S.Army: 'Use of Novel Technologies to ID and Investigate Molecular Markers for Ovarian Cancer Screening and Prevention', $854,545, 1998 to 2001.
  • National Institutes of Health (NIH): 'QOL Effects of Ovarian Cancer Risk Education and Screening', $429,005, 1997 to 2002.
  • National Institutes of Health (NIH): 'Use of Mammography Tumor Registry for Breast Cancer Research', $344,603, 1997 to 2002.
  • Department of Defense/U.S.Army: 'Reaching Rural Mammographers for Quality Improvement', $425,050, 1996 to 1999.
  • National Institutes of Health/National Cancer Institute: 'Effects on Quality of Life of Consumer Involvement in Treatment Decisions', $99,609, 1995 to 1996.
  • Department of Defense/U.S.Army: 'Development of a Stochastic Simulation Model of the Cost-Effectiveness of Promoting Breast Cancer Screening', $182,182, 1994 to 1998.
  • National Institutes of Health/National Cancer Institute: 'Pilot for a Community Mammography-Tumor Registry', $184,880, 1994 to 1997.
  • National Institutes of Health/National Cancer Institute: 'Community Trial of Breast Cancer Screening Promotion', $458,333, 1993 to 1998.

Publications

  • McIntosh M, Anderson G, Drescher C, Hanash S, Urban N, Brown P, Gambhir SS, Coukos G, Laird PW, Nelson B, Palmer C (Nov 2008) Ovarian cancer early detection claims are biased., Clinical cancer research : an official journal of the American Association for Cancer Research, 14 (22), 7574; author reply 7 Abstract
  • Feng Q, Deftereos G, Hawes SE, Stern JE, Willner JB, Swisher EM, Xi L, Drescher C, Urban N, Kiviat N (Nov 2008) DNA hypermethylation, Her-2/neu overexpression and p53 mutations in ovarian carcinoma., Gynecologic oncology, 111 (2), 320-9 Abstract
  • Lowe KA, Shah C, Wallace E, Anderson G, Paley P, McIntosh M, Andersen MR, Scholler N, Bergan L, Thorpe J, Urban N, Drescher CW (Sep 2008) Effects of personal characteristics on serum CA125, mesothelin, and HE4 levels in healthy postmenopausal women at high-risk for ovarian cancer., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 17 (9), 2480-7 Abstract
  • Andersen MR, Goff BA, Lowe KA, Scholler N, Bergan L, Dresher CW, Paley P, Urban N (Aug 2008) Combining a symptoms index with CA 125 to improve detection of ovarian cancer., Cancer, 113 (3), 484-9 Abstract
  • Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, Pogosova-Agadjanyan EL, Peterson A, Noteboom J, O'Briant KC, Allen A, Lin DW, Urban N, Drescher CW, Knudsen BS, Stirewalt DL, Gentleman R, Vessella RL, Nelson PS, Martin DB, Tewari M (Jul 2008) Circulating microRNAs as stable blood-based markers for cancer detection., Proceedings of the National Academy of Sciences of the United States of America, 105 (30), 10513-8 Abstract
  • Faca VM, Song KS, Wang H, Zhang Q, Krasnoselsky AL, Newcomb LF, Plentz RR, Gurumurthy S, Redston MS, Pitteri SJ, Pereira-Faca SR, Ireton RC, Katayama H, Glukhova V, Phanstiel D, Brenner DE, Anderson MA, Misek D, Scholler N, Urban ND, Barnett MJ, Edelstein C, Goodman GE, Thornquist MD, McIntosh MW, DePinho RA, Bardeesy N, Hanash SM (Jun 2008) A mouse to human search for plasma proteome changes associated with pancreatic tumor development., PLoS medicine, 5 (6), e123 Abstract
  • Scholler N, Lowe KA, Bergan LA, Kampani AV, Ng V, Forrest RM, Thorpe JD, Gross JA, Garvik BM, Drapkin R, Anderson GL, Urban N (May 2008) Use of yeast-secreted in vivo biotinylated recombinant antibodies (Biobodies) in bead-based ELISA., Clinical cancer research : an official journal of the American Association for Cancer Research, 14 (9), 2647-55 Abstract
  • Swisher EM, Sakai W, Karlan BY, Wurz K, Urban N, Taniguchi T (Apr 2008) Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum resistance., Cancer research, 68 (8), 2581-6 Abstract
  • Sakai W, Swisher EM, Karlan BY, Agarwal MK, Higgins J, Friedman C, Villegas E, Jacquemont C, Farrugia DJ, Couch FJ, Urban N, Taniguchi T (Feb 2008) Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers., Nature, 451 (7182), 1116-20 Abstract
  • Scholler N, Gross JA, Garvik B, Wells L, Liu Y, Loch CM, Ramirez AB, McIntosh MW, Lampe PD, Urban N (2008) Use of cancer-specific yeast-secreted in vivo biotinylated recombinant antibodies for serum biomarker discovery., Journal of translational medicine, 6, 41 Abstract
  • Palmer C, Duan X, Hawley S, Scholler N, Thorpe JD, Sahota RA, Wong MQ, Wray A, Bergan LA, Drescher CW, McIntosh MW, Brown PO, Nelson BH, Urban N (2008) Systematic evaluation of candidate blood markers for detecting ovarian cancer., PLoS ONE, 3 (7), e2633 Abstract
  • Bergan L, Gross JA, Nevin B, Urban N, Scholler N (Oct 2007) Development and in vitro validation of anti-mesothelin biobodies that prevent CA125/Mesothelin-dependent cell attachment., Cancer letters, 255 (2), 263-74 Abstract
  • Urban N, Longton GM, Crowe AD, Drucker MJ, Lehman CD, Peacock S, Lowe KA, Zeliadt SB, Gaul MA (Sep 2007) Computer-assisted mammography feedback program (CAMFP) an electronic tool for continuing medical education., Academic radiology, 14 (9), 1036-42 Abstract
  • Andersen MR, Drescher CW, Zheng Y, Bowen DJ, Wilson S, Young A, McIntosh M, Mahony BS, Lowe KA, Urban N (Sep 2007) Changes in cancer worry associated with participation in ovarian cancer screening., Psycho-oncology, 16 (9), 814-20 Abstract
  • McIntosh MW, Liu Y, Drescher C, Urban N, Diamandis EP (Aug 2007) Validation and characterization of human kallikrein 11 as a serum marker for diagnosis of ovarian carcinoma., Clinical cancer research : an official journal of the American Association for Cancer Research, 13 (15 Pt 1), 4422-8 Abstract
  • Simon I, Liu Y, Krall KL, Urban N, Wolfert RL, Kim NW, McIntosh MW (Jul 2007) Evaluation of the novel serum markers B7-H4, Spondin 2, and DcR3 for diagnosis and early detection of ovarian cancer., Gynecologic oncology, 106 (1), 112-8 Abstract
  • Scholler N, Garvik B, Hayden-Ledbetter M, Kline T, Urban N (Mar 2007) Development of a CA125-mesothelin cell adhesion assay as a screening tool for biologics discovery., Cancer letters, 247 (1), 130-6 Abstract
  • Thorpe JD, Duan X, Forrest R, Lowe K, Brown L, Segal E, Nelson B, Anderson GL, McIntosh M, Urban N (2007) Effects of blood collection conditions on ovarian cancer serum markers., PLoS ONE, 2 (12), e1281 Abstract
  • Goff BA, Mandel LS, Drescher CW, Urban N, Gough S, Schurman KM, Patras J, Mahony BS, Andersen MR (Jan 2007) Development of an ovarian cancer symptom index: possibilities for earlier detection., Cancer, 109 (2), 221-7 Abstract
  • Scholler N, Garvik B, Quarles T, Jiang S, Urban N (Dec 2006) Method for generation of in vivo biotinylated recombinant antibodies by yeast mating., Journal of immunological methods, 317 (1-2), 132-43 Abstract
  • Scholler N, Crawford M, Sato A, Drescher CW, O'Briant KC, Kiviat N, Anderson GL, Urban N (Apr 2006) Bead-based ELISA for validation of ovarian cancer early detection markers., Clinical cancer research : an official journal of the American Association for Cancer Research, 12 (7 Pt 1), 2117-24 Abstract
  • Stewart JJ, White JT, Yan X, Collins S, Drescher CW, Urban ND, Hood L, Lin B (Mar 2006) Proteins associated with Cisplatin resistance in ovarian cancer cells identified by quantitative proteomic technology and integrated with mRNA expression levels., Molecular & cellular proteomics : MCP, 5 (3), 433-43 Abstract
  • Goodell V, Salazar LG, Urban N, Drescher CW, Gray H, Swensen RE, McIntosh MW, Disis ML (Feb 2006) Antibody immunity to the p53 oncogenic protein is a prognostic indicator in ovarian cancer., Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 24 (5), 762-8 Abstract
  • Sato AH, Anderson GL, Urban N, McIntosh MW (2006) Comparing adaptive and non-adaptive algorithms for cancer early detection with novel biomarkers., Cancer biomarkers : section A of Disease markers, 2 (3-4), 151-62 Abstract
  • Bast RC Jr, Lilja H, Urban N, Rimm DL, Fritsche H, Gray J, Veltri R, Klee G, Allen A, Kim N, Gutman S, Rubin MA, Hruszkewycz A (Sep 2005) Translational crossroads for biomarkers., Clinical Cancer Research, 11 (17), 6103-8 Abstract
  • Andersen MR, Schroeder T, Gaul M, Moinpour C, Urban N (Feb 2005) Using a population-based cancer registry for recruitment of newly diagnosed patients with ovarian cancer., American journal of clinical oncology, 28 (1), 17-20 Abstract
  • Andersen MR, Abullarade J, Urban N (2005) Assertiveness with physicians is related to women's perceived roles in the medical encounter., Women & health, 42 (2), 15-33 Abstract
  • McIntosh MW, Drescher C, Karlan B, Scholler N, Urban N, Hellstrom KE, Hellstrom I (2004) Combining CA 125 and SMR serum markers for diagnosis and early detection of ovarian carcinoma., Gynecologic Oncology, 95 (1), 9-15 Abstract
  • Andersen MR, Urban N, Ramsey S, Briss PA (2004) Examining the cost-effectiveness of cancer screening promotion., Cancer, 101 (5 Suppl), 1229-38 Abstract
  • Andersen MR, Nelson J, Peacock S, Giedzinska A, Dresher C, Bowen D, Urban N (Aug 2004) Worry about ovarian cancer risk and use of screening by high-risk women: how you recruit affects what you find., American Journal of Medical Genetics. Part a, 129A (2), 130-5 Abstract
  • Drescher CW, Nelson J, Peacock S, Andersen MR, McIntosh MW, Urban N (Apr 2004) Compliance of average- and intermediate-risk women to semiannual ovarian cancer screening., Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology., 13 (4), 600-6 Abstract
  • Geller BM, Kerlikowske K, Carney PA, Abraham LA, Yankaskas BC, Taplin SH, Ballard-Barbash R, Dignan MB, Rosenberg R, Urban N, Barlow WE (Sep 2003) Mammography surveillance following breast cancer., Breast Cancer Research and Treatment, 81 (2), 107-15 Abstract
  • Balkwill F, Bast RC, Berek J, Chenevix-Trench G, Gore M, Hamilton T, Jacobs I, Mills G, Souhami R, Urban N, Orsulic S, Smyth J, Ursulic S ( Sep 2003) Current research and treatment for epithelial ovarian cancer. A PositionPaper from the Helene Harris Memorial Trust, , , 1818-27 pages
  • Urban N, McIntosh MW, Andersen M, Karlan BY (Aug 2003) Ovarian cancer screening., Hematology/oncology Clinics of North America, 17 (4), 989-1005, ix Abstract
  • Hellstrom I, Raycraft J, Hayden-Ledbetter M, Ledbetter JA, Schummer M, McIntosh M, Drescher C, Urban N, Hellstrom KE (Jul 2003) The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma., Cancer Research, 63 (13), 3695-700 Abstract
  • Andersen MR, Smith R, Meischke H, Bowen D, Urban N (Apr 2003) Breast cancer worry and mammography use by women with and without a family history in a population-based sample., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 12 (4), 314-20 Abstract
  • Etzioni R, Urban N, Ramsey S, McIntosh M, Schwartz S, Reid B, Radich J, Anderson G, Hartwell L (Apr 2003) The case for early detection., Nature Reviews. Cancer, 3 (4), 243-52 Abstract
  • Stone B, Schummer M, Paley PJ, Thompson L, Stewart J, Ford M, Crawford M, Urban N, O'Briant K, Nelson BH (Mar 2003) Serologic analysis of ovarian tumor antigens reveals a bias toward antigens encoded on 17q., International Journal of Cancer. Journal International Du Cancer, 104 (1), 73-84 Abstract
  • McIntosh MW, Urban N (Jan 2003) A parametric empirical Bayes method for cancer screening using longitudinal observations of a biomarker., Biostatistics (Oxford, England), 4 (1), 27-40 Abstract
  • Urban N (Jan 2003) Specific keynote: ovarian cancer risk assessment and the potential for early detection., Gynecologic Oncology, 88 (1 Pt 2), S75-9; discussion S8 Abstract
  • Andersen MR, Hager M, Su C, Urban N, Analysis of the cost-effectiveness of mammography promotion by volunteers in rural communities, Health Education and Behavior, 29(6), 755-70, December 2002
  • Ernster VL, Ballard-Barbash R, Barlow WE, Zheng Y, Weaver DL, Cutter G, Yankaskas BC, Rosenberg R, Carney PA at al., Detection of ductal carcinoma in situ in women undergoing screening mammography, Journal of the National Cancer Institute, 94(20), 1546-54, 16 Oct 2002
  • Thompson B, Thompson LA, Andersen MR, Hager S, Taylor V, Urban N, Costs and cost-effectiveness of a clinical intervention to increase mammography utilization in an inner city public health hospital, Preventive Medicine, 35(1), 87-96, July 2002 Abstract
  • Lehman C, Holt S, Peacock S, White E, Urban N, Use of the American College of Radiology BI-RADS guidelines by community radiologists: concordance of assessments and recommendations assigned to screening mammograms, AJR American Journal of Roentgenology, 179(1), 15-20, July 2002 Abstract
  • Urban N, Developing measures of mammography performance, Medical Care, 40(6 Suppl), III86-8, June 2002 Abstract
  • Andersen MR, Peacock S, Nelson J, Wilson S, McIntosh M, Drescher C, Urban N, Worry about ovarian cancer risk and use of ovarian cancer screening by women at risk for ovarian cancer, Gynecologic Oncology, 85(1), 3-8, April 2002 Abstract
  • Taplin SH, Ichikawa LE, Kerlikowske K, Ernster VL, Rosenberg RD, Yankaskas BC, Carney PA, Geller BM, Urban N, Dignan MB, Barlow WE, Ballard-Barbash R, Sickles EA, Concordance of breast imaging reporting and data system assessments and management recommendations in screening mammography, Radiology, 222(2), 529-35, February 2002 Abstract
  • McIntosh MW, Urban N, Karlan B, Generating longitudinal screening algorithms using novel biomarkers for disease, Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 11(2), 159-66, February 2002 Abstract
  • Geller BM, Barlow WE, Ballard-Barbash R, Ernster VL, Yankaskas BC, Sickles EA, Carney PA, Dignan MB, Rosenberg RD, Urban N, Zheng Y, Taplin SH (Feb 2002) Use of the American College of Radiology BI-RADS to report on the mammographic evaluation of women with signs and symptoms of breast disease., Radiology, 222 (2), 536-42 Abstract
  • Meischke H, Kuniyuki A, Yasui Y, Bowen DJ, Andersen R, Urban N (Feb 2002) Information women receive about heart attacks and how it affects their knowledge, beliefs, and intentions to act in a cardiac emergency., Health care for women international, 23 (2), 149-62 Abstract
  • Bast RC, Urban N, Shridhar V, Smith D, Zhang Z, Skates S, Lu K, Liu J, Fishman D, Mills G (2002) Early detection of ovarian cancer: promise and reality., Cancer treatment and research, 107, 61-97 Abstract
  • Stoddard AM, Fox SA, Costanza ME, Lane DS, Andersen MR, Urban N, Lipkus I, Rimer BK (Jan 2002) Effectiveness of telephone counseling for mammography: results from five randomized trials., Preventive medicine, 34 (1), 90-9 Abstract
  • Ramsey SD, Clarke L, Etzioni R, Higashi M, Berry K, Urban N (Oct 2001) Cost-effectiveness of microsatellite instability screening as a method for detecting hereditary nonpolyposis colorectal cancer., Annals of internal medicine, 135 (8 Pt 1), 577-88 Abstract
  • Stone B, Schummer M, Paley PJ, Crawford M, Ford M, Urban N, Nelson BH (Apr 2001) MAGE-F1, a novel ubiquitously expressed member of the MAGE superfamily., Gene, 267 (2), 173-82 Abstract
  • McIntosh M, Ramsey S, Berry K, Urban N (Jan 2001) Parameter solicitation for planning cost effectiveness studies with dichotomous outcomes., Health economics, 10 (1), 53-66 Abstract
  • Rosenberg RD, Yankaskas BC, Hunt WC, Ballard-Barbash R, Urban N, Ernster VL, Kerlikowske K, Geller B, Carney PA, Taplin S (Dec 2000) Effect of variations in operational definitions on performance estimates for screening mammography., Academic radiology, 7 (12), 1058-68 Abstract
  • Kerlikowske K, Carney PA, Geller B, Mandelson MT, Taplin SH, Malvin K, Ernster V, Urban N, Cutter G, Rosenberg R, Ballard-Barbash R (Dec 2000) Performance of screening mammography among women with and without a first-degree relative with breast cancer., Annals of internal medicine, 133 (11), 855-63 Abstract
  • Crump C, McIntosh MW, Urban N, Anderson G, Karlan BY (Oct 2000) Ovarian cancer tumor marker behavior in asymptomatic healthy women: implications for screening., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 9 (10), 1107-11 Abstract
  • Bowen DJ, Andersen MR, Urban N, Volunteerism in a community-based sample of women, aged 50 to 80 years, Journal of Applied Psychology, 30(9), 1829-42, September 2000
  • Ramsey SD, McIntosh M, Etzioni R, Urban N (Aug 2000) Simulation modeling of outcomes and cost effectiveness., Hematology/oncology clinics of North America, 14 (4), 925-38 Abstract
  • Carney PA, Geller BM, Moffett H, Ganger M, Sewell M, Barlow WE, Stalnaker N, Taplin SH, Sisk C, Ernster VL, Wilkie HA, Yankaskas B, Poplack SP, Urban N, West MM, Rosenberg RD, Michael S, Mercurio TD, Ballard-Barbash R (Aug 2000) Current medicolegal and confidentiality issues in large, multicenter research programs., American journal of epidemiology, 152 (4), 371-8 Abstract
  • Drescher C, Holt SK, Andersen MR, Anderson G, Urban N, Use of ovarian cancer screening among a general population sample in Washington State, Obstetrics and Gynecology, 96(1), 70-4, July 2000
  • Andersen MR, Yasui Y, Meischke H, Kuniyuki A, Etzioni R, Urban N (Apr 2000) The effectiveness of mammography promotion by volunteers in rural communities., American journal of preventive medicine, 18 (3), 199-207 Abstract
  • Ramsey SD, Andersen MR, Etzioni R, Moinpour C, Peacock S, Potosky A, Urban N (Mar 2000) Quality of life in survivors of colorectal carcinoma., Cancer, 88 (6), 1294-303 Abstract
  • Andersen MR, Hager M, Meischke H, Shaw C, Yasui Y, Urban N, Recruitment, retention and activity of volunteers promoting mammography use in rural communities, Health Promotion Practice, 1(4), 341-50, 2000
  • Lehman CD, White E, Peacock S, Drucker MJ, Urban N (Dec 1999) Effect of age and breast density on screening mammograms with false-positive findings., AJR. American journal of roentgenology, 173 (6), 1651-5 Abstract
  • Urban N (Nov 1999) Screening for ovarian cancer. We now need a definitive randomised trial., BMJ (Clinical research ed.), 319 (7221), 1317-8 Abstract
  • Edlefsen KL, Mandelson MT, McIntosh MW, Andersen MR, Wagner EH, Urban N, Prostate-specific antigen for prostate cancer screening. Do physician characteristics affect its use?, American Journal of Preventive Medicine, 17(1), 87-90, July 1999 Abstract
  • Desnick L, Taplin S, Taylor V, Coole D, Urban N, Clinical breast examination in primary care: perceptions and predictors among three specialties., Journal of Womens Health, 8(3), 389-97, April 1999 Abstract
  • Andersen MR, Urban N, Etzioni R (1999) Community attitudes and mammography use: does it really matter what other people think?, Women & health, 29 (3), 83-95 Abstract
  • Andersen MR, Urban N (1999) Involvement in decision-making and breast cancer survivor quality of life., Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 21 (3), 201-9 Abstract
  • Lewis CE, George V, Fouad M, Porter V, Bowen D, Urban N (Oct 1998) Recruitment strategies in the women's health trial: feasibility study in minority populations. WHT:FSMP Investigators Group. Women's Health Trial:Feasibility Study in Minority Populations., Controlled clinical trials, 19 (5), 461-76 Abstract
  • Meischke H, Andersen R, Bowen D, Kuniyuki A, Urban N, A health priorities model: application to mammography screening., Health Education and Behavior, 25(3), 383-95, June 1998 Abstract
  • Stoddard A M, Rimer B K, Lane D, Fox S A, Lipkus I, Luckmann R, Avrunin J S, Sprachman S, Costanza M, Urban N, Underusers of mammogram screening: stage of adoption in five U.S. subpopulations. The NCI Breast Cancer Screening Consortium., Preventive Medicine, 27(3), 478-87, May 1998 Abstract
  • Pepe M S, Urban N, Rutter C, Longton G, Design of a study to improve accuracy in reading mammograms, Journal of Clinical Epidemiology, 50(12), 1327-38, December 1997 Abstract
  • Ballard-Barbash R, Taplin S H, Yankaskas B C, Ernster V L, Rosenberg R D, Carney P A, Barlow W E, Geller B M, Kerlikowske K, Edwards B K, Lynch C F, Urban N, Chrvala C A, Key C R, Poplack S P, Worden J K, Kessler L G, Breast Cancer Surveillance Consortium: a national mammography screening and outcomes database., American Journal of Roentgenology, 169(4), 1001-8, October 1997 Abstract
  • Ramsey SD, Etzioni R, Troxel A, Urban N, Optimizing sampling strategies for estimating quality-adjusted life years., Medical Decision Making, 17(4), 431-8, October 1997 Abstract
  • Rakowski W, Andersen M R, Stoddard A M, Urban N, Rimer B K, Lane D S, Fox S A, Costanza M E, Confirmatory analysis of opinions regarding the pros and cons of mammography., Health Psychology, 16(5), 433-41, September 1997 Abstract
  • Urban N, Drescher C, Etzioni R, Colby C, Use of a stochastic simulation model to identify an efficient protocol for ovarian cancer screening, Controlled Clinical Trials, 18(3), 251-70, June 1997 Abstract
  • Taplin S H, Urban N, Taylor V M, Savarino J, Conflicting national recommendations and the use of screening mammography: does the physician's recommendation matter?, Journal of The American Board of Family Practice, 10(2), 88-95, Spring 1997 Abstract
  • Andersen M R, Urban N, Physician gender and screening: do patient differences account for differences in mammography use?, Women and Health, 26(1), 29-39, 1997 Abstract
  • Urban N, Drescher C, Clarke L, Kiviat N., Cost-effectiveness analysis of ovarian cancer screening strategies, Hungarian Journal of Gynecological Oncology (in Hungarian), 169-180, 1997
  • Bowen D, Clifford C K, Coates R, Evans M, Feng Z, Fouad M, George V, Gerace T, Grizzle J E, Hall W D, Hearn M, Henderson M, Kestin M, Kristal A, Leary E T, Lewis C E, Oberman A, Prentice R, Raczynski J, Toivola B, Urban N, The Women's Health Trial Feasibility Study in Minority Populations: design and baseline descriptions., Annals of Epidemiology, 6(6), 507-19, November 1996 Abstract
  • Taylor V M, Taplin S H, Urban N, White E, Mahloch J, Majer K, McLerran D, Peacock S, Community organization to promote breast cancer screening ordering by primary care physicians, Journal of Community Health, 21(4), 277-91, August 1996 Abstract
  • Etzioni R, Urban N, Baker M, Estimating the costs attributable to a disease with application to ovarian cancer, Journal of Clinical Epidemiology, 49(1), 95-103, January 1996 Abstract
  • Urban N, Taplin S H, Taylor V M, Peacock S, Anderson G, Conrad D, Etzioni R, White E, Montano D E, Mahloch J, et al, Community organization to promote breast cancer screening among women ages 50-75, Preventive Medicine, 24(5), 477-84, September 1995 Abstract
  • Taylor V M, Taplin S H, Urban N, White E, Peacock S, Repeat mammography use among women ages 50-75, Cancer Epidemiology, Biomarkers and Prevention, 4(4), 409-13, June 1995 Abstract
  • Taplin S H, Barlow W, Urban N, Mandelson M T, Timlin D J, Ichikawa L, Nefcy P, Stage, age, comorbidity, and direct costs of colon, prostate, and breast cancer care, Journal of The National Cancer Institute, 87(6), 417-26, 15 Mar 1995 Abstract
  • Taplin S H, Taylor V, Montano D, Chinn R, Urban N, Specialty differences and the ordering of screening mammography by primary care physicians, Journal of The American Board of Family Practice, 7(5), 375-86, Autumn 1994 Abstract
  • Taylor V M, Taplin S H, Urban N, Mahloch J, Majer K A, Medical community involvement in a breast cancer screening promotional project, Public Health Reports, 109(4), 491-9, Summer 1994 Abstract
  • Urban N, Anderson G L, Peacock S, Mammography screening: how important is cost as a barrier to use?, American Journal of Public Health, 84(1), 50-5, January 1994 Abstract
  • Thornquist M D, Urban N, Tseng A, Edelstein C, Lund B, Omenn G S, Research cost analyses to aid in decision making in the conduct of a large prevention trial, CARET. Carotene and Retinol Efficacy Trial, Controlled Clinical Trials, 14(4), 325-39, August 1993 Abstract
  • Urban N, Anderson G L, Tseng A, Effects on response rates and costs of stamps vs business reply in a mail survey of physicians, Journal of Clinical Epidemiology, 46(5), 455-9, May 1993 Abstract
  • White E, Urban N, Taylor V, Mammography utilization, public health impact, and cost-effectiveness in the United States, Annual Review of Public Health, 14, 605-33, 1993 Abstract
  • Kristal A R, White E, Shattuck A L, Curry S, Anderson G L, Fowler A, Urban N, Long-term maintenance of a low-fat diet: durability of fat-related dietary habits in the Women's Health Trial, Journal of The American Dietetic Association, 92(5), 553-9, May 1992 Abstract
  • Urban N, White E, Anderson G L, Curry S, Kristal A R, Correlates of maintenance of a low-fat diet among women in the Women's Health Trial, Preventive Medicine, 21(3), 279-91, May 1992 Abstract
  • White E, Shattuck A L, Kristal A R, Urban N, Prentice R L, Henderson M M, Insull W Jr, Moskowitz M, Goldman S, Woods M N, Maintenance of a low-fat diet: follow-up of the Women's Health Trial, Cancer Epidemiology, Biomarkers and Prevention, 1(4), 315-23, Spring 1992 Abstract
  • White E, Hurlich M, Thompson R S, Woods M N, Henderson M M, Urban N, Kristal A, Dietary changes among husbands of participants in a low-fat dietary intervention., American Journal of Preventive Medicine, 7(5), 319-25, Autumn 1991 Abstract
  • Schapira D V, Urban N, A minimalist policy for breast cancer surveillance, Jama, 265(3), 380-2, 16 Jan 1991 Abstract
  • Baker M S, Kessler L G, Urban N, Smucker R C, Estimating the treatment costs of breast and lung cancer, Medical Care, 29(1), 40-9, January 1991 Abstract
  • Urban N, Self S, Kessler L, Prentice R, Henderson M, Iverson D, Thompson D, Byar D, Insull W, Gorbach S L, et al, Analysis of the costs of a large prevention trial, Controlled Clinical Trials, 11(2), 129-46, April 1990 Abstract
  • Paskett E D, White E, Urban N, Gey G O, Hornecker J, Meadows S, Sifferman F R, Implementation and evaluation of a worksite breast self-examination training program, Progress In Clinical and Biological Research, 339, 281-302, 1990 Abstract
  • Meischke H, Yasui Y, Kuniyuki A, Bowen DJ, Andersen R, Urban N, How women label and respond to symptoms of acute myocardial infarction: responses to hypothetical symptom scenarios., Heart & lung : the journal of critical care, 28 (4), 261-9 Abstract
  • Stone B, Schummer M, Paley PJ, Thompson L, Stewart J, Ford M, Crawford M, Urban N, O'Briant K, Nelson BH, Serological analysis of ovarian tumor antigens reveals a bias towards antigens encoded on 17q, International Journal of Cancer

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