Dr. Jack Van Hoff |
|
Yale University School of Medicine Pediatrics Associate Professor |
Mailing AddressYale University School of Medicine Dept. of Pediatrics 333 Cedar St. New Haven, Connecticut 06520-8064United States | Contact Information |
Qualifications
M.D., University of Medicine and Dentistry of New Jersey, 1981.
B.S., Rensselaer Polytechnic Institute, Biology, 1977.
Expertise and Research Interests
Research efforts are directed primarily to cooperative group work within the Children's Oncology Group (COG).
Prior epidemiology work includes an analysis of trends in the incidence of childhood cancer in Connecticut as well as collaboration with researchers at the School of Epidemiology and Public Health on a case-control study of indoor radon levels and childhood cancer. Other past efforts include a case-control study of leukemia in regions of Belarus contaminated by the Chernobyl nuclear accident and establishment of a childhood cancer registry in the country of Belarus. Currently reviewing the role of Radiation therapy in pediatric brain tumors, using the SEER database.
In the past, independent research has focused on supportive care issues, primarily antiemetics and infectious complications of indwelling right atrial catheters in children. Past work within the Pediatric Oncology Group includes an earlier study detailing the use of VP-16, Ifosfamide and Cisplatin for recurrent solid tumors and coordination of a localized neuroblastoma therapy study. Current effort in the Children's Oncology Group is directed towards co-coordinating a low-risk ALL study, which has recently closed
Prior epidemiology work includes an analysis of trends in the incidence of childhood cancer in Connecticut as well as collaboration with researchers at the School of Epidemiology and Public Health on a case-control study of indoor radon levels and childhood cancer. Other past efforts include a case-control study of leukemia in regions of Belarus contaminated by the Chernobyl nuclear accident and establishment of a childhood cancer registry in the country of Belarus. Currently reviewing the role of Radiation therapy in pediatric brain tumors, using the SEER database.
In the past, independent research has focused on supportive care issues, primarily antiemetics and infectious complications of indwelling right atrial catheters in children. Past work within the Pediatric Oncology Group includes an earlier study detailing the use of VP-16, Ifosfamide and Cisplatin for recurrent solid tumors and coordination of a localized neuroblastoma therapy study. Current effort in the Children's Oncology Group is directed towards co-coordinating a low-risk ALL study, which has recently closed
Keywords
COS Keywords:
Biomedical Research Resources, Biomedical Research Resources, Other, Cancer Or Carcinogenesis, Chemotherapy, Clinical Trial, Epidemiology, Leukemia, Neoplasm, Pediatrics, Pharmacology, Risk Factor Analysis.Additional Terms:
Antineoplastic, Cancer Risk, Child, Clinical Trial, Combination Chemotherapy, Human Subject, Human Therapy Evaluation, Intravenous Administration, Neoplasm Cancer Chemotherapy, Neoplasm Cancer Pharmacology, Neoplasm Cancer Relapse Recurrence, Neuroblastoma, Pediatric Neoplasm Cancer.Memberships
American Society of Clinical Oncology
American Society of Pediatric Hematology/Oncology
Children's Oncology Group
Gold Humanism Honor Society
Honors and Awards
2002, Howard A Pearson Pediatric Faculty teaching Award,
Dept. Pediatrics Yale University School of Medicine,
Yale University
2002, Society of Distinguished Teachers,
Yale University School of Medicine,
Yale University
1998, NBI Healthcare Foundation Humanism in Medicine Award,
Newark Beth Isreal Healthcare Foundation
Publications
- Haykin M E, Gorman M, van Hoff J, Fulbright R K, Baehring J M, Diffusion-Weighted MRI Correlates of Subacute Methotrexate Related Neurotoxicity, J Neuro-Oncology, 23 Jul 2005
- McCarthy P L, Paltiel O, Maslova E, Kulikov S, Hahn T, Kopecky, K J, Drozdova V, Shmatina N, Tichonova L, van Hoff J, Gavrilova, I, Weinstein H, Histopathologic Verification of Acute Leukemia Cases in Belarus, Russia and Ukraine in a Cohort of 382 Patients, Leukemia Research, 28, 1273-1280, 1 Jul 2004
- Chunikhovskiy SP, Zelterman D, van Hoff J, Treatment of childhood acute lymphoblastic leukemia at a regional non-academic center in Belarus, Medical and Pediatric Oncology, 39, 202-206, 2002
- Mayer JLR, Pascale VJ, Clyne L, Malkus H, vanHoff J, Stability of low dose vancomycin hydrochloride in 100 IU/ml heparin sodium, Journal of Pharmacy Technology, 15, 2121-5, 1999
- Strother D, van Hoff J, Rao PV, Smith EI, Shamberger RC, Halperin EC, Murray KJ, Castleberry RP, Event-free survival of children with biologically favourable neuroblastoma based on the degree of initial tumour resection: Results from the Pediatric Oncology Group, European Journal of Cancer, 33(12), 2121-5, October 1997
- van Hoff J, Averkin Y I, Hilchenko E I, Prudyvus I S, Epidemiology of childhood cancer in Belarus: Review of data 1978-1994, and discussion of the new Belarusian Childhood Cancer Registry, Stem Cells, 15 Suppl 2, 231-41, 1997
- van Hoff J, Grier H E, Douglass E C, Green D M, Etoposide, ifosfamide, and cisplatin therapy for refractory childhood solid tumors. Response and toxicity, Cancer, 75(12), 2966-70, 15 Jun 1995
- Korn E, Van Hoff J, Buckley P, Daughaday W H, Carpenter T O, Secretion of a large molecular-weight form of insulin-like growth factor by a primary renal tumor, Medical and Pediatric Oncology, 24(6), 392-6, June 1995
- Shneider B L, Haque S, van Hoff J, Touloukian R J, West A B, Familial adenomatous polyposis following liver transplantation for a virilizing hepatoblastoma, Journal of Pediatric Gastroenterology and Nutrition, 15(2), 198-201, August 1992
- van Hoff J, Hockenberry-Eaton M J, Patterson K, Hutter J J, A survey of antiemetic use in children with cancer, American Journal of Diseases of Children, 145(7), 773-8, July 1991
- Komp D M, Buckley P J, McNamara J, van Hoff J, Soluble interleukin-2 receptor in hemophagocytic histiocytoses: Searching for markers of disease activity, Pediatric Hematology and Oncology, 6(3), 253-64, 1989
- van Hoff J, Olszewski O, Lorazepam for the control of chemotherapy related nausea and vomiting in children, Journal of Pediatrics, 113, 146-150, 1988
- van Hoff J, Ritchey A K, Pulse methylprednisolone for acute childhood idiopathic thrombocytopenic purpura, Journal of Pediatrics, 113, 563-566, 1988
- van Hoff J, Camitta B, Dreyer ZE, Patterson K, Roth E, Emami A: Antiemetic Efficacy of Lorazepam in Pediatric/Adolescent Cancer Chemotherapy. Int J Pediatr Hematol/Oncol 2:199-203, 1995
- van Hoff J, Berg AT, Seashore JH: The Effect of Right AtrialCatheters on Infectious Complications of Chemotherapy in Children. J Clin Oncol 8:1255-1262, 1990
- van Hoff J, Schymura MJ, McCrea Curnen MG: Trends in the Incidence of Childhood and Adolescent Cancer in Connecticut 1935-1979. Med Pediatr Oncol 16:78-87, 1988
Profile Details
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