Dr. Vicky L. van Santen

(Reading, Writing, Speaking)

US Poultry & Egg Association: Significance of Minor Viral Subpopulations within Ark-type Infectious Bronchitis Vaccines, 2008 to 2009.
United States Department of Agriculture (USDA): Effects of viral immunosuppression on disease in vaccinated chickens, 2007 to 2011.

• van Ginkel FW, van Santen VL, Gulley SL, Toro H (Dec 2008) Infectious bronchitis virus in the chicken Harderian gland and lachrymal fluid: viral load, infectivity, immune cell responses, and effects of viral immunodeficiency., Avian diseases, 52 (4), 608-17
• Schat, KA (2008) Chicken Infectious Anemia, Diseases of Poultry, 12 Edition, 211-235 pages, ISBN=9780813807188 (bookchapter)
• Sedlackova L, Perkins KD, Lengyel J, Strain AK, van Santen VL, Rice SA (May 2008) Herpes simplex virus type 1 ICP27 regulates expression of a variant, secreted form of glycoprotein C by an intron-retention mechanism., Journal of Virology, 82 (15), 7443-7455
• van Santen, VL (2008) Rapid selection in chickens of subpopulations within ArkDPI-derived infectious bronchitis virus vaccines, Avian Pathology, 37 (3), 293-306
• Joiner KS, Hoerr FJ, Ewald SJ, van Santen VL, Wright JC, van Ginkel FW, Toro H (Sep 2007) Pathogenesis of infectious bronchitis virus in vaccinated chickens of two different major histocompatibility B complex genotypes., Avian Diseases, 51 (3), 758-63
• van Santen VL, Toro H, Hoerr FJ (Mar 2007) Biological characteristics of chicken anemia virus regenerated from clinical specimen by PCR., Avian Diseases, 51 (1), 66-77
• Panangala VS, Shoemaker CA, Van Santen VL, Dybvig K, Klesius PH (Mar 2007) Multiplex-PCR for simultaneous detection of 3 bacterial fish pathogens, Flavobacterium columnare, Edwardsiella ictaluri, and Aeromonas hydrophila., Diseases of Aquatic Organisms, 74 (3), 199-208
• Christopherson PW, van Santen VL, Livesey L, Boudreaux MK (2007) A 10-base-pair deletion in the gene encoding platelet glycoprotein IIb associated with Glanzmann thrombasthenia in a horse., Journal of Veterinary Internal Medicine, 21 (1), 196-8
• Toro H, van Santen VL, Li L, Lockaby SB, van Santen E, Hoerr FJ (Dec 2006) Epidemiological and experimental evidence for immunodeficiency affecting avian infectious bronchitis., Avian Pathology, 35 (6), 455-64
• Christopherson PW, Insalaco TA, van Santen VL, Livesey L, Bourne C, Boudreaux MK (Jan 2006) Characterization of the cDNA Encoding alphaIIb and beta3 in normal horses and two horses with Glanzmann thrombasthenia., Veterinary Pathology, 43 (1), 78-82
• van Santen, V.L., Toro, H., van Ginkel, F.W., Joiner, K. S., Hoerr, F. J. (2006) Effects of chicken anemia virus and/or infectious bursal disease virus on infectious bronchitis virus infection and immune responses, V. International Symposium on Avian Corona- and Pneumoviruses and Complicating Pathogens, Rauischholzhausen, Germany, 14-16 May 2006, Giessen, VVB Laufersweiler Verlag, 296-299 pages
• Joiner KS, Ewald SJ, Hoerr FJ, van Santen VL, Toro H (Dec 2005) Oral infection with chicken anemia virus in 4-wk broiler breeders: lack of effect of major histocompatibility B complex genotype., Avian Diseases, 49 (4), 482-7
• Donofrio G, Cavirani S, van Santen V, Flammini CF (2005) Potential secondary pathogenic role for bovine herpesvirus 4, Journal of Clinical Microbiology, 43 (7), 3421-3426
• Panangala VS, van Santen VL, Shoemaker CA, Klesius PH (2005) Analysis of 16S-23S intergenic spacer regions of the rRNA operons in Edwardsiella ictaluri and Edwardsiella tarda isolates from fish., Journal of Applied Microbiology, 99 (3), 657-69
• van Santen VL, Joiner KS, Murray C, Petrenko N, Hoerr FJ, Toro H (2004) Pathogenesis of chicken anemia virus: comparison of the oral and the intramuscular routes of infection, Avian Diseases, 48 (3), 494-504
• van Santen VL, Kaltenboeck B, Joiner KS, Macklin KS, Norton RA (2004) Real-time quantitative PCR-based serum neutralization test for detection and titration of neutralizing antibodies to chicken anemia virus, Journal of Virological Methods, 115 (2), 123-135
• van Santen, V.L., Toro, H., Joiner, K. S., Hoerr, F. J. (2004) Experimental examination of interaction between chicken anemia virus and live attenuated IBV vaccine, IV. International Symposium on Avian Corona- and Pneumovirus Infections, 20-23 June 2004, Rauischholzhausen, Germany, 230-231 pages
• Donofrio G, Galli C, Lazzari G, van Santen VL, Cavirani S, Flammini CF (2003) Interaction of a green recombinant bovine herpesvirus 4 with in vitro-produced bovine embryos, Veterinary Research Communications, 27 (5), 415-424
• Donofrio G, Cavirani S, Simone T, van Santen VL (2002) Potential of bovine herpesvirus 4 as a gene delivery vector, Journal of Virological Methods, 101 (1-2), 49-61
• Donofrio G, van Santen VL (2001) A bovine macrophage cell line supports bovine herpesvirus-4 persistent infection, The Journal of General Virology, 82 (5), 1181-5
• van Santen VL, Li L, Hoerr FJ, Lauerman LH (2001) Genetic characterization of chicken anemia virus from commercial broiler chickens in Alabama, Avian Diseases, 45 (2), 373-88
• Ruffin DC, van Santen VL, Zhang Y, Voelker LL, Panangala VS, Dybvig K (2000) Transposon mutagenesis of Mycoplasma gallisepticum by conjugation with enterococcus faecalis and determination of insertion site by direct genomic sequencing, Plasmid, 44 (2), 191-195
• Donofrio G, Cavirani S, van Santen VL (2000) Establishment of a cell line persistently infected with bovine herpesvirus-4 by use of a recombinant virus., The Journal of General Virology, 81 (7), 1807-14
• Liu L, Dybvig K, Panangala VS, van Santen VL, French CT (2000) GAA trinucleotide repeat region regulates M9/pMGA gene expression in Mycoplasma gallisepticum, Infection and Immunity, 68 (2), 871-6
• Liu L, Payne DM, van Santen VL, Dybvig K, Panangala VS (1998) A protein (M9) associated with monoclonal antibody-mediated agglutination of mycoplasma gallisepticum is a member of the pMGA family, Infection and Immunity, 66 (11), 5570-5575
• Silverstein PS, van Santen VL, Nusbaum KE, Bird RC (1998) Expression kinetics and mapping of the thymidine kinase transcript and an immediate-early transcript from channel catfish virus, Journal of Virology, 72 (5), 3900-6
• Bermudez-Cruz R, Zhang L, van Santen VL (1998) Characterization of a bovine herpesvirus 4(BHV-4) 1.1-kb RNA and its transactivation by BHV-4 immediate-early 2 gene product., Archives of Virology, 143 (12), 2391-412
• Bermudez-Cruz R, Zhang L, van Santen VL (1997) Characterization of an abundant, unique 1.7-kilobase bovine herpesvirus 4 (BHV-4) late RNA and mapping of a BHV-4 IE2 transactivator-binding site in its promoter-regulatory region., Journal of Virology, 71 (1), 527-38
• Lomonte P, Bublot M, van Santen V, Keil G, Pastoret PP, Thiry E (1996) Bovine herpesvirus 4: genomic organization and relationship with two other gammaherpesviruses, Epstein-Barr virus and herpesvirus saimiri., Veterinary Microbiology, 53 (1-2), 79-89
• Zhang L, van Santen VL (1995) Interaction of bovine herpesvirus 4 (BHV-4) immediate early 2 gene product with BHV-4 thymidine kinase promoter-regulatory region., The Journal of General Virology, 76 (10), 2433-45
• Lomonte P, Bublot M, van Santen V, Keil GM, Pastoret PP, Thiry E (1995) Analysis of bovine herpesvirus 4 genomic regions located outside the conserved gammaherpesvirus gene blocks, The Journal of General Virology, 76 (7), 1835-41
• Silverstein PS, Bird RC, van Santen VL, Nusbaum KE (1995) Immediate-early transcription from the channel catfish virus genome: characterization of two immediate-early transcripts., Journal of Virology, 69 (5), 3161-6
• Galik PK, van Santen VL, Stringfellow DA, Bird RC, Wright JC, Smith PC (1993) Development of a DNA probe for identification of bovine herpesvirus 4., American Journal of Veterinary Research, 54 (5), 653-9
• van Santen VL (1993) Characterization of a bovine herpesvirus 4 immediate-early RNA encoding a homolog of the Epstein-Barr virus R transactivator., Journal of Virology, 67 (2), 773-84
• Lauerman LH, Hoerr FJ, Sharpton AR, Shah SM, van Santen VL (1993) Development and application of a polymerase chain reaction assay for Mycoplasma synoviae., Avian Diseases, 37 (3), 829-34
• Morsy MA, Panangala VS, van Santen VL, Bird RC (1993) Cloning and partial sequence analysis of a Mycoplasma synoviae DNA fragment encoding epitopes shared with the major adhesin P1 protein of Mycoplasma pneumoniae., Avian Diseases, 37 (4), 1105-12
• Chang LY, Van Santen VL (1992) Immediate-early, early, and late RNAs in bovine herpesvirus-4-infected cells., Virology, 191 (2), 909-20
• van Santen VL, Chang LY (1992) Cloning and mapping of EcoRI, HindIII, and PstI fragments of bovine herpesvirus 4 (DN-599) genome., Intervirology, 34 (1), 44-52
• van Santen VL (1991) Characterization of the bovine herpesvirus 4 major immediate-early transcript, Journal of Virology, 65 (10), 5211-24
• Surowy CS, van Santen VL, Scheib-Wixted SM, Spritz RA (1989) Direct, sequence-specific binding of the human U1-70K ribonucleoprotein antigen protein to loop I of U1 small nuclear RNA., Molecular and Cellular Biology, 9 (10), 4179-86
• Hamm J, van Santen VL, Spritz RA, Mattaj IW (1988) Loop I of U1 small nuclear RNA is the only essential RNA sequence for binding of specific U1 small nuclear ribonucleoprotein particle proteins., Molecular and Cellular Biology, 8 (11), 4787-91
• van Santen VL, Swain W, Spritz RA (1988) Nucleotide sequences of two soybean U1 snRNA genes., Nucleic Acids Research, 16 (9), 4176
• van Santen VL, Spritz RA (1987) Nucleotide sequence of a bean (Phaseolus vulgaris) U1 small nuclear RNA gene: implications for plant pre-mRNA splicing., Proceedings of the National Academy of Sciences of the United States of America., 84 (24), 9094-8
• van Santen VL, Spritz RA (1987) Splicing of plant pre-mRNAs in animal systems and vice versa., Gene, 56 (2-3), 253-65
• van Santen VL, Spritz RA (1986) Alternative splicing of SV40 early pre-mRNA in vitro., Nucleic Acids Research, 14 (24), 9911-26
• Giebel LB, van Santen VL, Slightom JL, Spritz RA (1985) Nucleotide sequence, evolution, and expression of the fetal globin gene of the spider monkey Ateles geoffroyi., Proceedings of the National Academy of Sciences of the United States of America., 82 (20), 6985-9
• Lang KM, van Santen VL, Spritz RA (1985) The two intervening sequences of human beta- and gamma-globin pre-mRNAs are excised in a preferred temporal order in vitro., The EMBO Journal, 4 (8), 1991-6
• van Santen VL, Spritz RA (1985) mRNA precursor splicing in vivo: sequence requirements determined by deletion analysis of an intervening sequence., Proceedings of the National Academy of Sciences of the United States of America., 82 (9), 2885-9
• Spritz RA, van Santen VL (1985) Deletion analysis of the human gamma-globin IVS2: sequence requirements for RNA splicing., Annals of the New York Academy of Sciences, 445, 10-19
• Fennewald S, van Santen V, Kieff E (1984) Nucleotide sequence of an mRNA transcribed in latent growth-transforming virus infection indicates that it may encode a membrane protein., Journal of Virology, 51 (2), 411-9
• Hennessy K, Heller M, van Santen V, Kieff E (1983) Simple repeat array in Epstein-Barr virus DNA encodes part of the Epstein-Barr nuclear antigen., Science, 220 (4604), 1396-8
• van Santen V, Cheung A, Hummel M, Kieff E (1983) RNA encoded by the IR1-U2 region of Epstein-Barr virus DNA in latently infected, growth-transformed cells, Journal of Virology, 46 (2), 424-33
• Kieff E, Dambaugh T, Heller M, King W, Cheung A, van Santen V, Hummel M, Beisel C, Fennewald S, Hennessy K, Heineman T (1982) The biology and chemistry of Epstein-Barr virus., The Journal of Infectious Diseases, 146 (4), 506-17
• Heller M, van Santen V, Kieff E (1982) Simple repeat sequence in Epstein-Barr virus DNA is transcribed in latent and productive infections, Journal of Virology, 44 (1), 311-20
• King W, Van Santen V, Kieff E (1981) Epstein-Barr virus RNA. VI. Viral RNA in restringently and abortively infected Raji cells, Journal of Virology, 38 (2), 649-60
• van Santen V, Cheung A, Kieff E (1981) Epstein-Barr virus RNA VII: size and direction of transcription of virus-specified cytoplasmic RNAs in a transformed cell line, Proceedings of the National Academy of Sciences of the United States of America., 78 (3), 1930-4