Kai Wang

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University of Iowa
College of Public Health
Biostatistics
Associate ProfessorAppointed: 2007

Mailing Address

C22-B GH
Iowa City, Iowa 52242
United States

Contact Information

Phone: (319) 384-5175
Fax: (319) 384-5018
kai-wang@uiowa.edu
http://www.public-health.uiowa.edu/academics/faculty/kai_wang.html

Qualifications

Ph.D., University of Iowa, Statistics, 1999.
M.A., University of Iowa, Economics, 1996.
M.A., Nankai University, Economics, 1989.
B.A., Lanzhou University, Mathematics, 1986.

Expertise and Research Interests

Areas of Research Interest:

* Statistical Genetics
* Computation and Algorithms
* Bioinformatics

Future Research

HNPP Prevalence in Patients with Multiple Surgically Treated Compression Neuropathies, Orthopaedic Research & Education Foundation (PI: Sander, Co-Investigator: Wang)

Molecular Biology of Syndromic Retinal Degeneration, NIH (PI: Sheffield, Co-Investigator: Wang)

The Iowa Center for the Neuroscience of Mental Disorders: Neural Systems and Circuits, Neurodevelopment, and Schizophrenia, NIH (PI: Andreason, Co-Investigator: Wang)

Powerful Methods for Mapping QTL with Selected Samples, NIH/NIMH (PI: Wang)

Predictors of Oral and Skeletal Bone Loss in Menopause, NIH (PI: Willing, Co-Investigator: Wang)

Keywords

COS Keywords:

Algorithms, Genetics, Informatics, Preventive Medicine, Public Health, Statistics.

Additional Terms:

Algorithms, Computation, Genetics, Informatics, Statistics.

Memberships

American Society of Human Genetics
International Biometric Society
International Genetic Epidemiology Society

Honors and Awards

2005, International Travel Grant, University of Iowa
2005, Mathematical and Physical Sciences Funding Program Award, University of Iowa
2001-2001, College of Public Health-College of Medicine New Investigator Research Award, College of Public Health, University of Iowa, Research
1995-1995, Ponder Fellowship, University of Iowa
1984-1984, Outstanding Study Award, Lanzhou University

Previous Positions

2005-2007, Associate Professor, University of Iowa, College of Public Health, Program in Public Health Genetics
2003-2005, Assistant Professor, University of Iowa, College of Public Health, Program in Public Health Genetics
1999-2003, Assistant Professor, University of Iowa, College of Public Health, Biostatistics
1999-1999, Research Assistant Professor, University of Alabama at Birmingham, Medicine, Medicine, Comprehenseive Cancer Center
1997-1998, Research Assistant, University of Iowa, Carver College of Medicine, Preventive Medicine and Environmental Health
1996-1996, Instructor, University of Iowa, Henry B. Tippie College of Business, Economics
1992-1997, Teaching Assistant, University of Iowa, Henry B. Tippie College of Business, Economics and Statistics and Acturial Science, Mathematical Sciences
1989-1992, Instructor, Nankai University, Mathematics

Funding Received

  • University of North Carolina: A Collaborative Linkage Study of Autism, $1,240,716, Jul 15, 1999 to Jun 30, 2003.
  • NIMH: Sampling models and methods for complex genetic diseases, $1,433,118, Jul 1, 1995 to Nov 30, 2004.
  • College of Public Health, University of Iowa: Linkage analysis under linkage disequilibrium and disease locus heterogeneity, $10,000, Jan 1, 2001 to Dec 31, 2001.
  • NIH: Elderly Cancer Survivors: Cognitive Outcomes and Markers of Neurodegeneration, , 2007 to 2012.
  • NHLBI: Genetic Markers of von Willebrand Disease, , 2007 to 2011.
  • NIEHS: Semi-volatile PCBs: Sources, Exposures, Toxicities, , 2006 to 2010.
  • NIH: Molecular Genetics of Hereditary Glaucoma, , 2006 to 2010.
  • University of Iowa: Locating Genes Responsible for Continuous Traits: A Software Tool, , 2005 to 2005.
  • WISEWOMAN: Enhanced Study Design, Data Entry and Analysis and Breast and Cervical Cancer Early Detection Program Data and Entry Analysis, , 2004 to 2004.
  • COM HHMI Pilot Collaborative Project: Genetic Mapping of Familial Adolescent Idiopathic Scoliosis, , 2003 to 2005.
  • NIH: Infrastructure to Facilitate Discovery of Autism, , 2002 to 2007.
  • NIH: Molecular Biology of Syndromic Retinal Degeneration, , 2002 to 2007.

Publications

  • Wang K (Apr 2008) Genetic association tests in the presence of epistasis or gene-environment interaction., Genetic epidemiology Abstract
  • Maddox C, Wang B, Kirby PA, Wang K, Ludewig G (Mar 2008) MUTAGENICITY OF 3-METHYLCHOLANTHRENE, PCB3, AND 4-OH-PCB3 IN THE LUNG OF TRANSGENIC BIGBLUE RATS., Environmental toxicology and pharmacology, 25 (2), 260-266 Abstract
  • Wang K, Abbott D (2008) Aprincipal components regression approach to multilocus genetic association studies, Genet Epidemiol, 32, 108-118
  • Bishop JR, Wang K, Moline J, Ellingrod VL (Dec 2007) Association analysis of the metabotropic glutamate receptor type 3 gene (GRM3) with schizophrenia., Psychiatric genetics, 17 (6), 358 Abstract
  • Wang K, Peng Y (2006) Quantitative-trait-locus mapping in the presence of locus heterogeneity, Ann Hum Genet, 70 (Pt 6), 882-92
  • Wang K, A Likelihood Approach for Quantitative-trait-loci Mapping With Selected Pedigrees, Biometrics, 61(2), 465-73, Jun 2005
  • Wang K, Sheffield VC (2005) A constrined likelihood approach to marker-trait association studies, Am J Hum Genet, 77, 768-80
  • Wang K, A note on the asymptotic properties of affected-sib-pair linkage tests, Annals of Human Genetics, 68(Pt 4), 367-75, July 2004 Abstract
  • Wang K, Peng Y (2003) Linkage analysis of systolic blood pressure: a score statistic and computer implementation, BMC Genet, 4 (Suppl 1), S77
  • Zhang X, Wang K (2003) Bivariate linkage analysis of cholesterol and triglyceride levels in Framingham heart study, BMC Genet, 4 (Suppl 1), S62
  • Yang X, Wang K, Huang J, Vieland VJ (2003) Genome-wide linkage analysis of blood pressure under locus heterogeneity, BMC Genet, 4 (Suppl 1), S78
  • Wang K, Score tests for epistasis models on quantitative traits using general pedigree data, Genetic Epidemiology, 25(4), 314-26, December 2003 Abstract
  • Morcuende JA, Minhas R, Dolan L, Stevens J, Beck J, Wang K, Weinstein SL, Sheffield V, Allelic Variants of Human Melatonin 1A Receptor in Patients with Familial Adolescent Idiopathic Scoliosis, Spine, 28(17), 2025-8, September 2003 Abstract
  • Wang K, Mapping quantitative trait loci using multiple phenotypes in general pedigrees, Human Heredity, 55, 1-15, 2003
  • Huang J, Wang K [In Zhang H, Huang J (Eds)], Development of modern statistics and related topics, (In Semiparametric methods for mapping quantitative trait loci), World Scientific, 262-71, 2003
  • Wang K, Huang J (2002) Score test for mapping quantitative-trait loci with sibships of arbitrary size when the dominance effect is not negligible, Genetic Epidemiology, 23 (4), 398-412
  • Wang K, Huang J, A score-statistic approach for the mapping of quantitative-trait loci with sibships of arbitrary size, American Journal of Human Genetics, 70(2), 412-24, February 2002 Abstract
  • Wang K, Efficient score statistics for mapping quantitative trait Loci with extended pedigrees, Human Heredity, 54(2), 57-68, 2002 Abstract
  • Vieland VJ, Wang K, Huang J, Power to detect linkage based on multiple sets of data in the presence of locus heterogeneity: comparative evaluation of model-based linkage methods for affected sib pair data, Human Heredity, 51(4), 199-208, 2001 Abstract
  • Huang J, Vieland VJ, Wang K, Nonparametric estimation of marginal distributions under bivariate truncatioin with application to testing for age-of-onset anticipation, Statistica Sinica, 11, 1047-68, 2001
  • Wang K, Huang J, Logue M, Vieland V, Combined multipoint analysis of multiple asthma data sets based on the posterior probability of linkage, Genetic Epidemiology, 21 Suppl 1, S73-8, 2001 Abstract
  • Wang K, Huang J, Vieland VJ, The consistency of the posterior probability of linkage, Annals of Human Genetics, 64(Pt 6), 533-53, November 2000 Abstract
  • Wang K, Vieland VJ, Huang J, A Bayesian approach to replication of linkage findings, Genetic Epidemiology, Suppl 1(17), S749-54, 1999
  • Barret S et al, Collabortive linkage study of autism, American Journal of Medical Genetics (Neuropsychiatric Genetics), 88, 609-15, 1999
  • Wang K, Chinese Statistical Analysis Software. Nankai University Press, 1990

Profile Details

Last Updated: 5/7/2008

COS Expertise ID #689281
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