Prof. John Leicester Williams

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University of Memphis
College of Engineering
Biomedical Engineering
ProfessorAppointed: 2008

Mailing Address

Biomedical Engineering
University of Memphis
330 Engineering Technology Building
Memphis, Tennessee 38152
United States

Contact Information

Phone: (901) 678-5485
Fax: (901) 678-5281
john.williams@memphis.edu

Qualifications

Ph.D., Northwestern University, Theoretical and Applied Mechanics, 1981.
M.S., Northwestern University, Theoretical and Applied Mechanics, 1979.
B.S., University of Hawaii, Biology, 1975.

Expertise and Research Interests

Orthopaedic and dental biomechanics
Joint kinematics, joint arthroplasty
Mechanical properties and microstructure of bone and growth plate cartilage
Finite element analysis of orthopaedic and dental implants
Theoretical and experimental study of ultrasound propagation through bone tissues
Design and analysis of devices for mechanical stimulation of cells and tissues

Keywords

COS Keywords:

Biomaterials, Biomechanics, Biomedical Engineering, Bone, Finite Element Analysis, Mechanical Engineering, Orthopedics, Surgery.

Additional Terms:

Growth Plate Cartilage Mechanics, Mechanical and Physical Properties of Bone, Orthopaedic Biomechanics.

Languages

(Reading, Writing, Speaking)

Dutch: (Fluent, Fluent, Fluent)
English: (Fluent, Fluent, Fluent)
Afrikaans: (Functional, Functional, Functional)
French: (Functional, Basic, Basic)
German: (Functional, Basic, Basic)

Memberships

American Society of Biomechanics
American Society of Mechanical Engineers - Bioengineering Division
Orthopaedic Research Society

Honors and Awards

2001-2002, Paul W. Myer Award, University of Missouri Dept of Orthopaedic Surgery
1998, Sylvia Sorkin Greenfield Award, American Association of Physicists in Medicine, Best scientific paper in Medical Physics in 1997 by SN Hwang, FW Wehrli and JL Williams

Previous Positions

2005-2008, Staff Engineer, DePuy, a Johnson & Johnson company
1999-2005, Associate Professor, University of Missouri-Kansas City, School of Dentistry, Oral Biology
1995-2005, Associate Professor, University of Missouri-Kansas City, School of Medicine, Orthopaedic Surgery
1995-2005, Director of Orthopaedic Surgery Research, University of Missouri-Kansas City, School of Medicine, Orthopaedic Surgery, Truman Medical Center
1988-1995, Director of Biomechanical Testing and Computation, University of Pennsylvania, School of Medicine, Orthopaedic Surgery, McKay Laboratory of Orthopaedic Surgery Research
1988-1995, Assistant Professor, University of Pennsylvania, School of Medicine, Orthopaedic Surgery
1986-1988, Director of the University Computer Aided Design and Engineering Center, Syracuse University
1985-1988, Assistant Professor, Syracuse University, L.C. Smith College of Engineering & Computer Science, Mechanical and Aerospace Engineering
1981-1985, Assistant Professor, Northeastern University, Engineering, Mechanical Engineering

Publications

  • Gomaa ST, Williams JL (2008) The Effect of Patellar Ligament Coronal-Plane Angle on Kinematics Following Fixed Bearing Cruciate Retaining Total Knee Arthroplasty, 54th Annual Mtng of the Orthopaedic Research Society, Orthopaedic Research Society, Chicago, IL, Orthopaedic Research Society, #1971 pages
  • Williams JL, Gomaa ST (2008) Computational Knee Models of Mobile Bearing Implants Predict Differences in Kinematics During Simulated Squat and Lunge Deep Knee Bending Activities, 8th International Symposium on Computer Methods in Biomechanics and Biomedical Engineerin, Cardiff, UK, Meditech, #99 pages, In Press
  • Williams JL, Gomaa ST (2008) Traction Forces In Deep Knee Bending Of Rotating Platform Total Knee Implants And Implications For Wear, 17th meeting of the European Orthopaedic Research Society, European Orthopaedic Research Society
  • Williams JL, Gomaa ST (2008) Kinematics of Rotating Platform Total Knee Replacements - Does the Position of the Rotating Platform Axis Matter?, Proceedings of the 3rd Frontiers in Biomedical Devices Conference, American Society of Mechanical Engineers, New York, NY, American Society of Mechanical Engineers, #38083 pages
  • Petrie CS, Williams JL (Oct 2007) Probabilistic analysis of peri-implant strain predictions as influenced by uncertainties in bone properties and occlusal forces., Clinical oral implants research, 18 (5), 611-9 Abstract
  • Beall MS, Copley LA, Niemann JJ, Lankachandra K, Williams JL (2007) Biomechanical evaluation of fetal calf skull as a model for testing halo-pin designs for use in children., Journal of biomechanics, 40 (5), 1137-44 Abstract
  • Post ZD, Basran HS, Koreckij JT, Williams JL (2007) Microstructural Finite Element Model of Growth Cartilage Under Tension Based on the Substructuring Approach, 7th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering, Cardiff, UK, Meditech, #65 pages
  • Petrie CS, Williams JL (2007) Probabilistic Analysis of The Influence of Bone Properties and Occlusal Loading on Predicted Bone Strains Around a Single Mandibular Implant, 7th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering, Cardiff, UK, Meditech, #66 pages
  • Gomaa ST, Williams JL (2007) Kinematics of Total Knee Replacement: Indirect Comparison of Virtual Knee Simulation and In Vivo Fluoroscopy During Deep Knee Bending, 53rd Annual Mtng of the Orthopaedic Research Society, Orthopaedic Research Society, Chicago, IL, Orthopaedic Research Society, #1830 pages
  • Gomaa ST, Williams JL (2007) Tibial Component Posterior Slope Influences Knee Kinematics in Cruciate-Retaining Fixed-Bearing Total Knee Arthroplasty, Transactions of the Sixth Combined Mtg Orthop. Research Societies, Combined Orthopaedic Research Societies, Chicago, IL, Orthopaedic Research Society, #485 pages
  • Snyder RR, Williams JL, Schmidt TL, Salsbury TL (2006) Torsional strength of double- versus single-screw fixation in a pig model of unstable slipped capital femoral epiphysis., Journal of pediatric orthopedics, 26 (3), 295-9 Abstract
  • Petrie CS, Williams JL (Aug 2005) Comparative evaluation of implant designs: influence of diameter, length, and taper on strains in the alveolar crest. A three-dimensional finite-element analysis., Clinical Oral Implants Research, 16 (4), 486-94 Abstract
  • Snyder RR, Harlan CS, Williams JL, Schmidt TL (2005) Torsional Strength of Single- Versus Double-Screw Fixation in a Model of Slipped Capital Femoral Epiphysis, 51st Annual Mtng of the Orthopaedic Research Society, Orthopaedic Research Society, Chicago, IL, Orthopaedic Research Society
  • Chuinard, CR, Williams, JL, Schmidt, TL (2004) Torsional Strength of the Femoral Capital Epiphyseal Plate, Transactions of the 5th Combined Meeting of the Orthopaedic Research Societies of The USA, Canada, Europe, and Japan, p. 30, Orthopaedic Research Society
  • Galligan, JD, Williams, JL, Schmidt, TL, Hamilton, JJ (2004) Contribution of the Perichondrium to Shear Strength after Single Screw Fixation in Slipped Capital Femoral Epiphysis, 50th Annual Mtng of the Orthopaedic Research Society, Orthopaedic Research Society
  • Laughlin, GA, Williams, JL, Eick, JD (2003) An Elasto-Viscoplastic Finite Element Model for Predicting Polymerization Stresses in Light-Activated Dental Composites, ASME International Mechanical Engineering Congress, pp. 297-298, American Society of Mechanical Engineers
  • Datta, JC, Amin, AR, Williams, JL, Hamilton, JJ, Schmidt TL (2003) Shear Strength of the Proximal Tibial Tuberosity's Cartilage Bridge, Proceedings of the 2003 Summer Bioengineering Conference, pp. 1163-4, American Society of Mechanical Engineers
  • Shah, AA, Williams, JL, Hamilton, JJ, Fiorella, RM, Amin, AR (2003) Microstructural Tensile Properties of Two Different Growth Plates in the Proximal Femora of Calves: A Mechanical and Histological Comparison, Proceedings of the 2003 Summer Bioengineering Conference, pp. 1253-4, American Society of Mechanical Engineers
  • Laughlin, GA, Williams, JL, Eick, JD (2003) Nonlinear Finite Element Analysis of Dental Composite Curing Behavior, Transactions of the 29th Annual Meeting of the Society for Biomaterials, p. 179, Society for Biomaterials
  • Schneider, SB, Ipsen, BJ, Williams, JL, Schmidt, TL, Hamilton, JJ (2003) Contribution of the Perichondrial Ring to Shear Strength of the Capital Femoral Epiphysis Before and After Experimental Slip, Transactions of the 49th Annual Meeting of the Orthopaedic Research Society, p. 1244, Orthopaedic Research Society
  • Ipsen, BJ, Williams, JL, Harris, MJ, Schmidt, TL (2003) Shear Strength of Allograft Bone Screw Fixation in Slipped Capital Femoral Epiphysis, Transactions of the 49th Annual Meeting of the Orthopaedic Research Society, p. 1243, Orthopaedic Research Society
  • Petrie CS, Williams JL, Shape optimization of dental implant designs under oblique loading using the p-version finite element method, Journal of Mechanics in Medicine and Biology, 2(3 & 4), 339-345, December 2002
  • Laughlin GA, Williams JL, Eick JD (2002) The influence of system compliance and sample geometry on composite polymerization shrinkage stress., Journal of biomedical materials research, 63 (5), 671-8 Abstract
  • Ipsen, BJ, Williams, JL, Harris, MJ, Schmidt, TL (2002) Shear Strength of the Pig Capital Femoral Epiphyseal Plate - An Experimental Model for Human Slipped Capital Femoral Epiphysis Fixation Studies, Proceedings of IMECE2002 ASME International Mechanical Engineering Congress & Exposition, paper no. 32611, American Society of Mechanical Engineers
  • O'Mahony AM, Williams JL, Spencer P (Dec 2001) Anisotropic elasticity of cortical and cancellous bone in the posterior mandible increases peri-implant stress and strain under oblique loading., Clinical oral implants research, 12 (6), 648-57 Abstract
  • Williams JL, Do PD, Eick JD, Schmidt TL (Nov 2001) Tensile properties of the physis vary with anatomic location, thickness, strain rate and age., Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 19 (6), 1043-8 Abstract
  • Williams JL, Is there a causal relationship between quantitative ultrasound and the elastic constants of cancellous bone?, Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research, 16(5), 966-9, May 2001
  • Williams, jl, Gove, NK, Flowers, GA, Schmidt, TL (2001) Fracture Toughness of the Growth Cartilage Reserve Zone is Anisotropic, 2001 ASME International Mechanical Engineering Congress and Exposition, paper no. 23066, American Society of Mechanical Engineers
  • Williams, JL, Cob, CM, Schmidt , TL (2001) Morphology of Cryofractured Growth Plate Cartilage as Revealed by Scanning Electron Microscopy In Hvid, I (eds), Transactions of the 4th Combined Meeting of the Orthopaedic Research Societies of The USA, Canada, Europe, and Japan, p. 80. Chicago, Orthopaedic Research Society
  • Tutorino, JC, Khubchandani, ZG, Williams, JL, Cobb, CM (2001) Can the Epiphyseal Growth Plate be Injured in Compression? In Trippel, BS (eds), Trans. of the 47th Annual Meeting of the Orthop. Res. Soc, p. 353. Chicago, Orthopaedic Research Society
  • O'Mahony AM, Williams JL, Katz JO, Spencer P (Oct 2000) Anisotropic elastic properties of cancellous bone from a human edentulous mandible., Clinical oral implants research, 11 (5), 415-21 Abstract
  • Moon, BS, Williams, JL, Schmidt, TL (2000) Trans. of the 46th Annual Meeting of the Orthop. Res. Soc In Puzas, JE (eds), Fracture Toughness of Growth Plate Cartilage, p. 988. Chicago, Orthopaedic Research Society
  • Williams JL, Vani JN, Eick JD, Petersen EC, Schmidt TL (Mar 1999) Shear strength of the physis varies with anatomic location and is a function of modulus, inclination, and thickness., Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 17 (2), 214-22 Abstract
  • Karduna AR, Williams GR, Iannotti JP, Williams JL (Feb 1998) Total shoulder arthroplasty biomechanics: a study of the forces and strains at the glenoid component., Journal of biomechanical engineering, 120 (1), 92-9 Abstract
  • Scilaris TA, Grantham JL, Prayson MJ, Marshall MP, Hamilton JJ, Williams JL (1998) Biomechanical comparison of fixation methods in transverse patella fractures., Journal of orthopaedic trauma, 12 (5), 356-9 Abstract
  • Prayson MJ, Williams JL, Marshall MP, Scilaris TA, Lingenfelter EJ (Nov 1997) Biomechanical comparison of fixation methods in transverse olecranon fractures: a cadaveric study., Journal of orthopaedic trauma, 11 (8), 565-72 Abstract
  • Karduna AR, Williams GR, Williams JL, Iannotti JP (Aug 1997) Glenohumeral joint translations before and after total shoulder arthroplasty. A study in cadavera., The Journal of bone and joint surgery. American volume, 79 (8), 1166-74 Abstract
  • Hwang SN, Wehrli FW, Williams JL (Aug 1997) Probability-based structural parameters from three-dimensional nuclear magnetic resonance images as predictors of trabecular bone strength., Medical physics, 24 (8), 1255-61 Abstract
  • Grimm MJ, Williams JL (Jul 1997) Measurements of permeability in human calcaneal trabecular bone., Journal of biomechanics, 30 (7), 743-5 Abstract
  • Grimm MJ, Williams JL (Jul 1997) Assessment of bone quantity and 'quality' by ultrasound attenuation and velocity in the heel., Clinical biomechanics (Bristol, Avon), 12 (5), 281-285 Abstract
  • Karduna AR, Williams GR, Williams JL, Iannotti JP (1997) Joint stability after total shoulder arthroplasty in a cadaver model., Journal of shoulder and elbow surgery / American Shoulder and Elbow Surgeons ... [et al.], 6 (6), 506-11 Abstract
  • Karduna AR, Williams GR, Williams JL, Iannotti JP (Nov 1996) Kinematics of the glenohumeral joint: influences of muscle forces, ligamentous constraints, and articular geometry., Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 14 (6), 986-93 Abstract
  • Brighton CT, Fisher JR, Levine SE, Corsetti JR, Reilly T, Landsman AS, Williams JL, Thibault LE (Sep 1996) The biochemical pathway mediating the proliferative response of bone cells to a mechanical stimulus., The Journal of bone and joint surgery. American volume, 78 (9), 1337-47 Abstract
  • Williams, JL, Grimm, MJ, Wehrli, FW, Foster, KR, Chung, H-W (1996) Prediction of Frequency and Pore Size Dependent Attenuation of Ultrasound in Trabecular Bone Using Biot's Theory In Selvadurai, APS (eds), Mechanics of Poroelastic Media, 1st Edition, Dordrecht, The Netherlands, Kluwer Academic Publishers, 263-271 pages (bookchapter)
  • Chung HW, Wehrli FW, Williams JL, Wehrli SL (Oct 1995) Three-dimensional nuclear magnetic resonance microimaging of trabecular bone., Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 10 (10), 1452-61 Abstract
  • Hung CT, Williams JL (Feb 1994) A method for inducing equi-biaxial and uniform strains in elastomeric membranes used as cell substrates., Journal of biomechanics, 27 (2), 227-32 Abstract
  • Williams JL, Iannotti JP, Ham A, Bleuit J, Chen JH (1994) Effects of fluid shear stress on bone cells., Biorheology, 31 (2), 163-70 Abstract
  • Chung H, Wehrli FW, Williams JL, Kugelmass SD (Nov 1993) Relationship between NMR transverse relaxation, trabecular bone architecture, and strength., Proceedings of the National Academy of Sciences of the United States of America, 90 (21), 10250-4 Abstract
  • Squillante RG, Williams JL (Apr 1993) Videodensitometry of osteons in females with femoral neck fractures., Calcified tissue international, 52 (4), 273-7 Abstract
  • Wehrli FW, Ford JC, Chung HW, Wehrli SL, Williams JL, Grimm MJ, Kugelmass SD, Jara H (1993) Potential role of nuclear magnetic resonance for the evaluation of trabecular bone quality., Calcified tissue international, 53 Suppl 1, S162-9 Abstract
  • Barth RW, Williams JL, Kaplan FS (Oct 1992) Osteon morphometry in females with femoral neck fractures., Clinical orthopaedics and related research (283), 178-86 Abstract
  • Williams JL, Chen JH, Belloli DM (Aug 1992) Strain fields on cell stressing devices employing clamped circular elastic diaphragms as substrates., Journal of biomechanical engineering, 114 (3), 377-84 Abstract
  • Brighton CT, Sennett BJ, Farmer JC, Iannotti JP, Hansen CA, Williams JL, Williamson J (May 1992) The inositol phosphate pathway as a mediator in the proliferative response of rat calvarial bone cells to cyclical biaxial mechanical strain., Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 10 (3), 385-93 Abstract
  • Williams JL (Feb 1992) Ultrasonic wave propagation in cancellous and cortical bone: prediction of some experimental results by Biot's theory., The Journal of the Acoustical Society of America, 91 (2), 1106-12 Abstract
  • Austriaco NR, Williams JL, Drummond DS (Nov 1991) Trabecular bone densitometry using interactive image analysis., Journal of biomedical engineering, 13 (6), 486-8 Abstract
  • Brighton CT, Strafford B, Gross SB, Leatherwood DF, Williams JL, Pollack SR (Mar 1991) The proliferative and synthetic response of isolated calvarial bone cells of rats to cyclic biaxial mechanical strain., The Journal of bone and joint surgery. American volume, 73 (3), 320-31 Abstract
  • Williams, JL (1991) Chapter 42. Biomechanics of Total Hip Arthroplasty In Steinberg, ME (eds), The Hip and Its Disorders, 1st Edition, Philadelphia, W.B. Saunders Company, 876-904 pages (bookchapter)
  • Ryan SD, Williams JL (1989) Tensile testing of rodlike trabeculae excised from bovine femoral bone., Journal of biomechanics, 22 (4), 351-5 Abstract
  • Williams JL, Johnson WJ (1989) Elastic constants of composites formed from PMMA bone cement and anisotropic bovine tibial cancellous bone., Journal of biomechanics, 22 (6-7), 673-82 Abstract
  • Williams JL, Comment on the paper 'Response of a human head/neck/upper-torso replica to dynamic loading--II. Analytical/numerical model', Journal of Biomechanics, 21(8), 687-8, 1988
  • Belytschko, T, Williams, J, Rencis, M, Head-Spine Structure Modeling: Enhancements to Secondary Loading Path Model and Validation of Head-Cervical Spine Model, Aerospace Medical Research Laboratory, Report AAMRL-TR-85-019, Wright Patterson Air Force Base, Ohio, Harry G. Armstrong Aerospace Medical Research Laboratory, 127, 1985
  • Williams JL, Belytschko TB (Nov 1983) A three-dimensional model of the human cervical spine for impact simulation., Journal of biomechanical engineering, 105 (4), 321-31 Abstract
  • Williams JL, Lewis JL (Feb 1982) Properties and an anisotropic model of cancellous bone from the proximal tibial epiphysis., Journal of biomechanical engineering, 104 (1), 50-6 Abstract
  • Williams, JL, Belytschko, TB, A Dynamic Model of the Cervical Spine and Head, Report AFAMRL-TR-81-5, Wright-Patterson Air Force Base, Aerospace Medical Research Laboratory, 1981

Profile Details

Last Updated: 6/26/2009

COS Expertise ID #687105
Reference this profile directly: http://myprofile.cos.com/williams259