Donald Wong

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Indiana University
School of Medicine
Anatomy & Cell Biology
Neuroscience & Clinical Neurology
Course DirectorAppointed: 1994
Indiana University
School of Medicine
Otoloayngology-Head & Neck Surgery
Associate ProfessorAppointed: 1994

Mailing Address

Medical Science 5022
Indianapolis, Indiana 46202-5120
United States

Contact Information

Phone: (317) 274-2788
Fax: (317) 278-2040
wong@anatomy.iupui.edu

Qualifications

Ph.D., Columbia University, Anatomy, 1981.
B.S., Cornell University, Physics/Biophysics, 1973.

Expertise and Research Interests

A central interest of our research is to understand how the brain processes complex sounds in generating auditory perception. Extracellular single-unit recording is used to analyze the functional organization of the mammalian auditory cortex. Neuroanatomical tract-tracing is employed to determine the anatomical connections of physiologically-identified regions. A computational neuroscience approach is further used to model single neurons with artificial neural-networks and signal-processing techniques.

A second area of research is directed at plasticity in the central auditory pathway. The auditory nerve of drug-deafened animals is electrically stimulated to mimic the clinical condition found in profoundly-deaf patients surgically implanted with cochlear prostheses. 'Artificial' nerve stimulation in deafened animals will be evaluated for its potential to reverse nerve degeneration and induce functional reorganization.

A third area will use positron-emission tomography (PET) to image the human cerebral cortex, and compare regions activated by speech in both normal-hearing and profoundly-deaf patients fitted with different prosthetic devices.

Keywords

COS Keywords:

Acoustics, Anatomy, Brain, Cell Biology, Hearing, Hearing Disorders, Higher Education, Public, Nervous System, Neuroanatomy, Neurophysiology, Sensory System, Sonar Systems, USA, Midwest.

Additional Terms:

Acoustics, Brain, Communicative Disorders, Hearing, Communicative Disorders, Speech, Hearing, Higher Education, Public, Medical/Diagnostic Imaging, Nervous System, Neuroanatomy, Neurophysiology, Prosthetic Device, Hearing, Sensory System, Sonar Systems, USA, Midwest.

Publications

  • Hsieh L, Gandour J, Wong D, Hutchins GD, Functional heterogeneity of inferior frontal gyrus is shaped by linguistic experience, Brain and Language, 76(3), 227-52, March 2001 Abstract
  • Gandour J, Wong D, Hsieh L, Weinzapfel B, Van Lancker D, Hutchins GD, A crosslinguistic PET study of tone perception, Journal of Cognitive Neuroscience, 12(1), 207-22, Jan 2000 Abstract
  • Miyamoto RT, Wong D, Pisoni DB, Hutchins G, Sehgal M, Fain R, Positron emission tomography in cochlear implant and auditory brain stem implant recipients, American Journal of Otology, 20(5), 596-601, September 1999 Abstract
  • Wong D, Miyamoto RT, Pisoni DB, Sehgal M, Hutchins GD, PET imaging of cochlear-implant and normal-hearing subjects listening to speech and nonspeech., Hearing Research, 132(1-2), 34-42, June 1999 Abstract
  • Titze IR, Wong D, Milder MA, Hensley SR, Ramig LO, Comparison between clinician-assisted and fully automated procedures for obtaining a voice range profile, Journal of Speech and Hearing Research, 38(3), 526-35, June 1995 Abstract
  • Chittajallu SK, Wong D, Connectionist networks in auditory system modeling, Computers in Biology and Medicine, 24(6), 431-9, November 1994 Abstract
  • Paschal WG, Wong D, Frequency organization of delay-sensitive neurons in the auditory cortex of the FM bat, Myotis lucifugus, Journal of Neurophysiology, 72(1), 366-79, July 1994 Abstract
  • Maekawa M, Wong D, Paschal WG, Spectral selectivity of FM-FM neurons in the auditory cortex of the echolocating bat, Myotis lucifugus, Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology, 171(4), 513-22, November 1992 Abstract
  • Tanaka H, Wong D, Taniguchi I, The influence of stimulus duration on the delay tuning of cortical neurons in the FM bat, Myotis lucifugus, Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology, 171(1), 29-40, August 1992 Abstract

Profile Details

Last Updated: 4/8/2002

COS Expertise ID #804905
Reference this profile directly: http://myprofile.cos.com/wong7