Dr. Linda M. Zangwill

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University of California, San Diego
School of Medicine
Ophthalmology
Hamilton Glaucoma Center
ProfessorAppointed: 2005
University of California, San Diego
School of Medicine
Ophthalmology
Diagnostic Imaging Laboratory
DirectorAppointed: 1995
Professional Headshot of Linda M. Zangwill

Mailing Address

University of California, San Diego
Department of Ophthalmology
Hamilton Glaucoma Center
9500 Gilman Drive 0946
La Jolla, California 92093-0946
United States

Contact Information

Phone: (858) 534-7686
Fax: (858) 822-0499
zangwill@glaucoma.ucsd.edu

Qualifications

Ph.D., Ben-Gurion University of the Negev, Epidemiology, 1992.
M.Sc., Harvard University, Health Policy and Management, 1984.
B.S., University of California, Berkeley, Nutrition and Food Science, 1980.

Expertise and Research Interests

As an epidemiologist in the Department of Ophthalmology, I am interested in the distribution and characteristics of eye disease, in particular glaucoma, in human populations. I am currently involved in the following projects: (1) investigating new methods for detecting and measuring glaucomatous optic neuropathy and monitoring its progression; (2) studying the relationship between structural changes in the optic nerve and alteration of visual function; and (3) identification of characteristics of persons at an increased risk of developing glaucoma.

More specifically, I am the principal investigator of a National Eye Institute study evaluating the ability of new diagnostic imaging instruments to detect glaucomatous damage to the optic nerve and to monitor its progression. The ability to detect early signs of glaucoma and its progression at the site of damage, the optic nerve, may help ophthalmologists better understand the disease and initiate treatment at the most appropriate time.

Through the Imaging Data Evaluation and Analysis (IDEA) Center, I have developed procedures for utilization of these diagnostic imaging instruments in international mutli-center clinical trials of glaucoma and ocular hypertension. We hope that collaboration between research centers will help answer some of the difficult questions in glaucoma research.

Other Expertise

Dr. Zangwill is recognized for her work in evaluating new imaging techniques including confocal scanning laser ophthalmoscopy, scanning laser polarimetry and optical coherence tomography, for the diagnosis of glaucoma and monitoring its progression.

Dr. Zangwill accepts applications for post-doctoral fellows intersted in clinical research in glaucoma. Please contact her at zangwill@glaucoma.ucsd.edu

Keywords

COS Keywords:

Blindness, Epidemiology, Eye Diseases, Health Care Administration, Health Care Planning Or Policy, Hypertension, Medical Diagnosis, Ophthalmology, Vision.

Additional Terms:

Epidemiology, Eye Disorder Diagnosis, Glaucoma, Longitudinal Human Study.

Memberships

American Public Health Association
Association for Research in Vision and Ophthalmology
Association for Women in Science
Glaucoma Society of the International Congress of Ophthalmology
International Perimetric Society
Sam and Rose Stein Institute for Research on Aging
Women in Ophthalmology

Honors and Awards

2006-2006, Achievement Award, American Academy of Ophthalmology
1998-1998, Travel Award, San Diego Academic Senate, University of California, San Diego
1992-1992, Travel Fellowship, Association for Research in Vision and Ophthalmology, National Eye Institute

Previous Positions

2000-2005, Associate Professor, University of California, San Diego, School of Medicine, Ophthalmology
1993-1995, Research Assistant Professor, University of Waterloo, Applied Health Sciences, Health Studies and Gerontology, Institute For Risk Research
1993-2000, Assistant Professor, University of California, San Diego, School of Medicine, Ophthalmology
1992-1993, Post-doctoral Fellow, University of Waterloo, Institute For Risk Research
1991-1992, Research Associate, McMaster University, Health Sciences, Clinical Epidemiology and Biostatistics
1984-1991, Research Coordinator, Ben-Gurion University, Middle East Eye Research Institute and Health Services Evaluation Unit
1983-1983, Health Policy Analyst, Harvard University, Health Policy, Research and Education

Funding Received

  • National Institutes of Health (NIH): African Americans with Glaucoma: Structure and Function, 2002 to 2007.
  • National Institutes of Health (NIH): Functional Magnetic Resonance Imaging (fMRI) in glaucoma and healthy eyes, 2002 to 2005.
  • National Institutes of Health (NIH): Diagnostic Imaging in Glaucoma Study (DIGS): Structural Assessment, 1995 to 2011.
  • National Institutes of Health (NIH): Quantitative Analysis of Optic Disc/Ocular Hypertension, (Weinreb, RN, PI), 1995 to 2010.

Publications

  • Vizzeri G, Balasubramanian M, Bowd C, Weinreb RN, Zangwill LM (2009) Spectral domain optical coherence tomography to detect localized retinal nerve fiber layer defects in glaucomatous eyes, Opt Express, 17, 4004-18
  • Balasubramanian M, Bowd C, Vizzeri G, Weinreb RN, Zangwill LM (2009) Effect of image quality on tissue thickness measurements obtained with spectral-domain optical coherence tomography, Opt Express, 17, 4019-36
  • Sample PA, Girkin CA, Zangwill LM, Jain S, Racette L, Becerra LM, Weinreb RN, Medeiros FA, Wilson MR, De Leon-Ortega J, Bowd C, Liebmann JM, ADAGES Study Group (2009) The African Descent and Glaucoma Evaluation Study (ADAGES): Design and baseline data., Arch Ophthalmol, In Press
  • Vizzeri G, Weinreb RN, Gonzalez-Garcia AO, Bowd C, Medeiros FA, Sample PA, Zangwill LM (2009) Agreement between spectral-domain and time-domain OCT for measuring RNFL thickness., Br J Ophthalmol, In Press
  • Gonzalez-Garcia AO, Vizzeri G, Bowd C, Medeiros FA, Zangwill LM, Weinreb RN (2009) Reproducibility of RTVue retinal nerve fiber layer thickness and optic disc measurements and agreement with stratus OCT measurements., Am J Ophthalmol, In Press
  • Medeiros FA, Alencar LM, Zangwill LM, Bowd C, Vizzeri G, Sample PA, Weinreb RN (2009) Detection of progressive retinal nerve fiber layer in glaucoma using scanning laser polarimetry with variable corneal compensation, Invest Ophthalmol Vis Sci, In Press
  • Ng M, Racette L, Pascual JP, Liebmann JM, Girkin CA, Lovell SL, Zangwill LM, Weinreb RN, Sample PA (2009) Comparing the full threshold and Swedish interactive thresholding algorithms for short-wavelength automated perimetry., Invest Ophthalmol Vis Sci, In Press
  • Tafreshi A, Sample PA, Liebmann JM, Girkin CA, Zangwill LM, Weinreb RN, Lalezary M, Racette L (2009) Visual function specific perimetry to identify glaucomatous visual loss using three different definitions of visual field abnormality, Invest Ophthalmol Vis Sci, 50, 1234-40
  • Bowd C, Tafreshi A, Vizzeri G, Zangwill LM, Sample PA, Weinreb RN (2009) Repeatability of pattern electroretinogram measurements using a new paradigm optimized for glaucoma detection, J Glaucoma, In Press
  • Bowd C, Vizzeri G, Tafreshi A, Zangwill LM, Sample PA, Weinreb RN (2009) Diagnostic accuracy of pattern electroretinogram optimized for glaucoma detection (PERGLA), Ophthalmology, 116, 437-43
  • Vizzeri G, Weinreb RN, Martiniz de la Casa JM, Alencar LM, Bowd C, Balasubramanian M, Medeiros FA, Sample PA, Zangwill LM (2009) Clinicians agreement in establishing glaucomatous progression using the Heidelberg retina tomograph, Ophthalmology, 116, 14-24
  • Vizzeri G, Bowd C, Medeiros FA, Weinreb RN, Zangwill LM (2009) Scan tracking coordinates for improved centring of Stratus OCT scan pattern, J Glaucoma, 18, 81-7
  • Bowd C, Balasubramanian M, Weinreb RN, Vizzeri G, Alencar LM, O'Leary N, Sample PA, Zangwill LM (2009) Performance of confocal scanning laser tomograph Topographic Change Analysis (TCA) for assessing glaucomatous progression., Invest Ophthalmol Vis Sci, 50, 691-701
  • Vizzeri G, Bowd C, Medeiros FA, Weinreb RN, Zangwill LM (2008) Effect of improper scan alignment on retinal nerve fiber layer thickness measurements using stratus optical coherence tomograph., J Glaucoma, 17, 341-9
  • Medeiros FA, Weinreb RN, Zangwill LM, Alencar LM, Sample PA, Vasile C, Bowd C (2008) Long-term intraocular pressure fluctuations and risk of conversion from ocular hypertension to glaucoma, Ophthalmology, 115, 934-40
  • Medeiros FA, Vizzeri G, Zangwill LM, Alencar LM, Sample PA, Weinreb RN (2008) Comparison of retinal nerve fiber layer and optic disc imaging for diagnosing glaucoma in patients suspected of having the disease, Ophthalmology, 115, 1340-6
  • Alencar LM, Bowd C, Weinreb RN, Zangwill LM, Sample PA, Medeiros FA (2008) Comparison of HRT3 glaucoma probability score and subjective stereophotograph assessment for prediction of progression in glaucoma suspects, Invest Ophthalmol Vis Sci, 49, 1898-906
  • Bowd C, Hao J, Tavares IM, Medeiros FA, Zangwill LM, Lee T-W, Sample PA, Weinreb RN, Goldbaum MH (2008) Bayesian machine learning classifiers for combining structural and functional measurements to classify healthy and glaucomatous eyes, Invest Ophthalmol Vis Sci, 49, 945-53
  • Racette L, Medeiros FA, Zangwill LM, Ng D, Weinreb RN, Sample PA (2008) Diagnostic accuracy of the Matrix 24-2 and original N-30 frequency-doubling technology tests compared with standard automated perimetry, Invest Ophthalmol Vis Sci, 49, 954-60
  • Lu K, Perthen JE, Duncan RO, Zangwill LM, Liu TT (2008) Non-invasive measurement of cerebral blood flow response in human lateral geniculate nucleus with arterial spin labeling fMRI., Hum Brain Mapp, 29, 1207-14
  • Boden C, Chan K, Sample PA, Hao J, Lee T-W, Zangwill LM, Weinreb RN, Goldbaum MH (2007) Assessing visual field clustering schemes using machine learning classifiers in standard perimetry, Invest Ophthalmol Vis Sci, 48, 5582-90
  • Bourne RR, Jahanbakhsh K, Boden C, Zangwill LM, Hoffmann EM, Medeiros FA, Weinreb RN, Sample PA (2007) Reproducibility of visual field end point criteria for standard automated perimetry, full-thresholding Algorithm Strategies: Diagnostic Innovations in Glaucoma Study, Am J Ophthalmol, 143, 908-13
  • Racette L, Medeiros FA, Bowd C, Zangwill LM, Weinreb RN, Sample PA (2007) The impact of perimetric measurement scale, sample composition, and statistical method on the structure-function relationship in glaucoma, J Glaucoma, 16, 676-84
  • Medeiros FA, Ng D, Zangwill LM, Sample PA, Bowd C, Weinreb RN (2007) The effects of study design and spectrum bias on the evaluation of diagnostic accuracy of confocal scanning laser ophthalmoscopy in glaucoma, Invest Ophthalmol Vis Sci, 48, 214-22
  • Hoffmann EM, Boden C, Zangwill LM, Bowd C, Medeiros FA, Crowston JG, Sample PA, Weinreb RN (2007) Intereye spatial relationship of abnormal neuroretinal rim locations in glaucoma patients from the Diagnostic Innovations in Glaucoma Study, Am J Ophthalmol, 143, 781-7
  • Medeiros FA, Zangwill LM, Bowd C, Vasile C, Sample PA, Weinreb RN (2007) Agreement between stereophotographic and confocal scanning laser ophthalmoscopy measurements of cup/disc ratio: effect on a predictive model for glaucoma development, J Glaucoma, 16, 209-14
  • Pascual JP, Schiefer U, Paetzold J, Zangwill LM, Tavares IM, Weinreb RN, Sample PA (2007) Spatial characteristics of visual field progression determined by monte carlo simulation, Invest Ophthalmol Vis Sci, 48, 1642-50
  • Leung CK, Medeiros FA, Zangwill LM, Sample PA, Bowd C, Ng D, Cheung CY, Lam DS, Weinreb RN (2007) American Chinese glaucoma imaging study: a comparison of the optic disc and retinal nerve fiber layer in detecting glaucomatous damage, Invest Ophthalmol Vis Sci, 48, 2644-52
  • Medeiros FA, Bowd C, Zangwill LM, Patel C, Weinreb RN (2007) Detection of glaucoma using scanning laser polarimetry with enhanced corneal compensation., Invest Ophthalmol Vis Sci, 48, 3146-53
  • Racette L, Medeiros FA, Bowd C, Zangwill LM, Weinreb RN, Sample PA (2007) The impact of perimetric measurement scale, sample composition, and statistical method on the structure-function relationship in glaucoma, J Glaucoma, 16, 676-84
  • Medeiros FA, Doshi R, Zangwill LM, Vasile C, Weinreb RN (2007) Long-term variability of GDx VCC reintal nerve fiber layer thickness measurements, J Glaucoma, 16, 277-81
  • Zangwill LM, Jain S, Racette L, Ernstrom KB, Bowd C, Medeiros FA, Sample PA, Weinreb RN (2007) The effect of disc size and severity of disease on the diagnostic accuracy of the Heidelberg Retinal Tomograph (HRT) Glaucoma Probability Score and Moorfields Regression Analysis, Invest Ophthalmol Vis Sci, 48, 2653-60
  • Medeiros FA, Ng D, Zangwill LM, Sample PA, Bowd C, Weinreb RN (2007) The effects of study design and spectrum bias on the evaluation of diagnostic accuracy of confocal scanning laser ophthalmoscopy in glaucoma, Invest Ophthalmol Vis Sci, 48, 214-22
  • Bowd C, Medeiros FA, Weinreb RN, Zangwill LM (2007) The effect of atypical birefringence patterns on glaucoma detection using scanning laser polarimetry with variable corneal compensation., Invest Ophthalmol Vis Sci, 48, 223-7
  • Hoffmannn EM, Zangwill LM, Crowston JG, Weinreb RN (2007) Optic disk size and glaucoma., Surv Ophthalmol, 52, 32-49
  • Kim T-W, Zangwill LM, Bowd C, Sample PA, Shah N, Weinreb RN (2007) Retinal nerve fiber layer damage as assessed by optical coherence tomography in eyes with visual field defect detected by frequency doubling technology perimetry but not by standard automated perimetry, Ophthalmology, 114, 1053-7
  • Duncan RO, Sample PA, Weinreb RN, Bowd C, Zangwill LM (2007) Retinotopic organization of primary visual cortex in glaucoma: comparing fMRI mesaurements of cortical function with visual field loss, Prog Retin Eye Res, 26, 38-56
  • Duncan RO, Sample PA, Weinreb RN, Bowd C, Zangwill LM (2007) Retinotopic organization of primary visual cortex in glaucoma: a method for comparing cortical function with damage to the optic disk, Invest Ophthalmol Vis Sci, 48, 733-44
  • Bowd C, Tavares IM, Medeiros FA, Zangwill LM, Sample PA, Weinreb RN (2007) Association between retinal nerve fiber layer thickness and visual sensitivity using scanning laser polarimetry with variable and enhanced corneal compensation., Ophthalmology, 114, 1259-65
  • Racette L, Boden C, Kleinhandler SL, Girkin CA, Liebmann JM, Zangwill LM, Medeiros FA, Bowd C, Weinreb RN, Wilson MR, Sample PA (2006) Optic nerve structure in healthy subjects - in reply, Arch Ophthalmol, 124, 1508-9
  • Ng D, Zangwill LM, Racette L, Bowd C, Pascual JP, Bourne RR, Weinreb RN, Sample PA (2006) Agreement and repeatability between Standard Automated Perimetry and Confocal Scanning Laser Ophthalmoscopy in the Diagnostic Innovations in Glaucoma Study., Am J Ophthalmol, 142, 381-6
  • Shah NN, Bowd C, Medeiros FA, Weinreb RN, Sample PA, Hoffmann EM, Zangwill LM (2006) Combining structural and functional testing for detection of glaucoma., Ophthalmology, 113, 1593-602
  • Lalezary M, Medeiros FA, Weinreb RN, Bowd C, Sample PA, Tavares IM, Tafreshi A, Zangwill LM (2006) Baseline Optical Coherence Tomography to predict glaucomatous change in the Diagnostic Innovations in Glaucoma Study (DIGS)., American Journal of Ophthalmology, 142, 576-82
  • Sample PA, Medeiros FA, Racette L, Pascual JP, Boden C, Zangwill LM, Bowd C, Weinreb RN (2006) Identifying glaucomatous vision loss with visual-function-specific perimetry in the Diagnostic Innovations in Glaucoma Study., Investigative Ophthalmology & Visual Science, 47, 3381-9
  • Bowd C, Zangwill LM, Medeiros FA, Tavares IM, Hoffmann EM, Bourne RR, Sample PA, Weinreb RN (2006) Structure-function relationships using confocal scanning laser ophthalmoscopy, optical coherence tomography and scanning laser polarimetry., Investigative Ophthalmology & Visual Science, 47, 2889-95
  • Boden C, Hoffmann EM, Medeiros FA, Zangwill LM, Weinreb RN, Sample PA (2006) Inter-eye concordance in locations of visual field defects in primary open angle glaucoma: Diagnostic Innovations in Glaucoma Study., Ophthalmology, 113, 918-23
  • Medeiros FA, Sample PA, Zangwill LM, Liebmann JM, Girkin CG, Weinreb RN (2006) A statistical approach to evaluate covariate effects on the receiver operating characteristic curves of diagnostic tests in glaucoma., Investigative Ophthalmology & Visual Science, 47, 2520-7
  • Zangwill LM, Bowd C (2006) Retinal nerve fiber layer analysis in the diagnosis of glaucoma., Current Opinion in Ophthalmology, 17, 120-31
  • Medeiros FA, Zangwill LM, Bowd C, Sample PA, Weinreb RN (2006) Influence of disease severity and optic disc size on the diagnostic performance of imaging instruments in glaucoma., Investigative Ophthalmology & Visual Science, 47, 1008-15
  • Hoffmann EM, Boden C, Zangwill LM, Bourne RR, Weinreb RN, Sample PA (2006) Inter-eye comparison of patterns of visual field loss in patients with glaucomatous optic neuropathy., American Journal of Ophthalmology, 141, 703-8
  • Hoffmann EM, Medeiros FA, Sample PA, Boden C, Bowd C, Bourne RRA, Zangwill LM, Weinreb RN (2006) Relationship between patterns of visual field loss and retinal nerve fiber layer thickness measurements., American Journal of Ophthalmology, 141, 463-71
  • Medeiros FA, Weinreb RN, Sample PA, Gomi CF, Bowd C, Crowston JG, Zangwill LM (Oct 2005) Validation of a predictive model to estimate the risk of conversion from ocular hypertension to glaucoma., Archives of Ophthalmology, 123 (10), 1351-60 Abstract
  • Zangwill LM, Weinreb RN, Beiser JA, Berry CC, Cioffi GA, Coleman AL, Trick G, Liebmann JM, Brandt JD, Piltz-Seymour JR, Dirkes KA, Vega S, Kass MA, Gordon MO (Sep 2005) Baseline topographic optic disc measurements are associated with the development of primary open-angle glaucoma: the Confocal Scanning Laser Ophthalmoscopy Ancillary Study to the Ocular Hypertension Treatment Study., Archives of Ophthalmology, 123 (9), 1188-97 Abstract
  • Medeiros FA, Zangwill LM, Bowd C, Sample PA, Weinreb RN (Jun 2005) Use of progressive glaucomatous optic disk change as the reference standard for evaluation of diagnostic tests in glaucoma., American Journal of Ophthalmology, 139 (6), 1010-8 Abstract
  • Bowd C, Medeiros FA, Zhang Z, Zangwill LM, Hao J, Lee TW, Sejnowski TJ, Weinreb RN, Goldbaum MH (Apr 2005) Relevance vector machine and support vector machine classifier analysis of scanning laser polarimetry retinal nerve fiber layer measurements., Investigative Ophthalmology & Visual Science, 46 (4), 1322-9 Abstract
  • Bourne RR, Medeiros FA, Bowd C, Jahanbakhsh K, Zangwill LM, Weinreb RN (Apr 2005) Comparability of retinal nerve fiber layer thickness measurements of optical coherence tomography instruments., Investigative Ophthalmology & Visual Science, 46 (4), 1280-5 Abstract
  • Zangwill LM, Abunto T, Bowd C, Angeles R, Schanzlin DJ, Weinreb RN (Feb 2005) Scanning laser polarimetry retinal nerve fiber layer thickness measurements after LASIK., Ophthalmology, 112 (2), 200-7 Abstract
  • Henderson PA, Medeiros FA, Zangwill LM, Weinreb RN (Feb 2005) Relationship between central corneal thickness and retinal nerve fiber layer thickness in ocular hypertensive patients., Ophthalmology, 112 (2), 251-6 Abstract
  • Hoffmann EM, Bowd C, Medeiros FA, Boden C, Grus FH, Bourne RR, Zangwill LM, Weinreb RN (2005) Agreement among three Optical Imaging Methods for the Assessment of Optic Disk Topography., Ophthalmology, 112, 2149-56
  • Racette L, Boden C, Kleinhandler SL, Girkin CA, Liebmann JM, Zangwill LM, Medeiros FA, Bowd C, Weinreb RN, Wilson MR, Sample PA (2005) Differences in visual function and optic nerve structure between healthy eyes of Blacks and Whites., Archives of Ophthalmology, 123, 1547-53
  • Goldbaum MH, Sample PA, Zhang Z, Chan K, Hao J, Lee TW, Boden C, Bowd C, Bourne RRA, Zangwill LM, Sejnowski T, Spinak D, Weinreb RN (2005) Using unsupervised learning with independent component analysis to identify patterns of glaucomatous visual field defects., Investigative Ophthalmology & Visual Science, 46, 3676-83
  • Sample PA, Boden C, Zhang Z, Pascual JP, Lee TW, Zangwill LM, Weinreb RN, Crowston JG, Hoffmann EM, Medeiros FA, Sejnowski T, Goldbaum MH (2005) Unsupervised machine learning with independent component analysis to identify areas of progression in glaucomatous visual fields, Investigative Ophthalmology & Visual Science, 46, 3684-92
  • Medeiros FA, Zangwill LM, Bowd C, Vessani RM, Susanna R Jr, Weinreb RN (Jan 2005) Evaluation of retinal nerve fiber layer, optic nerve head, and macular thickness measurements for glaucoma detection using optical coherence tomography., American Journal of Ophthalmology, 139 (1), 44-55 Abstract
  • Sanchez-Galeana CA, Bowd C, Zangwill LM, Sample PA, Weinreb RN (Oct 2004) Short-wavelength automated perimetry results are correlated with optical coherence tomography retinal nerve fiber layer thickness measurements in glaucomatous eyes., Ophthalmology, 111 (10), 1866-72 Abstract
  • Mohammadi K, Bowd C, Weinreb RN, Medeiros FA, Sample PA, Zangwill LM (Oct 2004) Retinal nerve fiber layer thickness measurements with scanning laser polarimetry predict glaucomatous visual field loss., American Journal of Ophthalmology, 138 (4), 592-601 Abstract
  • Zangwill LM, Chan K, Bowd C, Hao J, Lee TW, Weinreb RN, Sejnowski TJ, Goldbaum MH (Sep 2004) Heidelberg retina tomograph measurements of the optic disc and parapapillary retina for detecting glaucoma analyzed by machine learning classifiers., Investigative Ophthalmology & Visual Science, 45 (9), 3144-51 Abstract
  • Hare WA, WoldeMussie E, Weinreb RN, Ton H, Ruiz G, Wijono M, Feldmann B, Zangwill L, Wheeler L (Aug 2004) Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, II: Structural measures., Investigative Ophthalmology & Visual Science, 45 (8), 2640-51 Abstract
  • Bowd C, Zangwill LM, Medeiros FA, Hao J, Chan K, Lee TW, Sejnowski TJ, Goldbaum MH, Sample PA, Crowston JG, Weinreb RN (Jul 2004) Confocal scanning laser ophthalmoscopy classifiers and stereophotograph evaluation for prediction of visual field abnormalities in glaucoma-suspect eyes., Investigative Ophthalmology & Visual Science, 45 (7), 2255-62 Abstract
  • Medeiros FA, Zangwill LM, Bowd C, Weinreb RN (Jun 2004) Comparison of the GDx VCC scanning laser polarimeter, HRT II confocal scanning laser ophthalmoscope, and stratus OCT optical coherence tomograph for the detection of glaucoma., Archives of Ophthalmology, 122 (6), 827-37 Abstract
  • Medeiros FA, Zangwill LM, Bowd C, Mohammadi K, Weinreb RN (May 2004) Comparison of scanning laser polarimetry using variable corneal compensation and retinal nerve fiber layer photography for detection of glaucoma., Archives of Ophthalmology, 122 (5), 698-704 Abstract
  • Angeles R, Abunto T, Bowd C, Zangwill LM, Schanzlin DJ, Weinreb RN (Apr 2004) Corneal changes after laser in situ keratomileusis: measurement of corneal polarization magnitude and axis., American Journal of Ophthalmology, 137 (4), 697-703 Abstract
  • Zangwill LM, Weinreb RN, Berry CC, Smith AR, Dirkes KA, Liebmann JM, Brandt JD, Trick G, Cioffi GA, Coleman AL, Piltz-Seymour JR, Gordon MO, Kass MA, OHTS CSLO Ancillary Study Group (Feb 2004) The confocal scanning laser ophthalmoscopy ancillary study to the ocular hypertension treatment study: study design and baseline factors., American Journal of Ophthalmology, 137 (2), 219-27 Abstract
  • Zangwill LM, Weinreb RN, Berry CC, Smith AR, Dirkes KA, Coleman AL, Piltz-Seymour JR, Liebmann JM, Cioffi GA, Trick G, Brandt JD, Gordon MO, Kass MA, Confocal Scanning Laser Ophthalmoscopy Ancillary Study to the Ocular Hypertension Treatment Study (Jan 2004) Racial differences in optic disc topography: baseline results from the confocal scanning laser ophthalmoscopy ancillary study to the ocular hypertension treatment study., Archives of Ophthalmology, 122 (1), 22-8 Abstract
  • Mansberger SL, Zangwill LM, Sample PA, Choi D, Weinreb RN (Nov 2003) Relationship of optic disk topography and visual function in patients with large cup-to-disk ratios., American Journal of Ophthalmology, 136 (5), 888-94 Abstract
  • El Beltagi TA, Bowd C, Boden C, Amini P, Sample PA, Zangwill LM, Weinreb RN (Nov 2003) Retinal nerve fiber layer thickness measured with optical coherence tomography is related to visual function in glaucomatous eyes., Ophthalmology, 110 (11), 2185-91 Abstract
  • Medeiros FA, Sample PA, Zangwill LM, Bowd C, Aihara M, Weinreb RN (Nov 2003) Corneal thickness as a risk factor for visual field loss in patients with preperimetric glaucomatous optic neuropathy., American Journal of Ophthalmology, 136 (5), 805-13 Abstract
  • Blumenthal EZ, Sample PA, Berry CC, Lee AC, Girkin CA, Zangwill L, Caprioli J, Weinreb RN (Oct 2003) Evaluating several sources of variability for standard and SWAP visual fields in glaucoma patients, suspects, and normals., Ophthalmology, 110 (10), 1895-902 Abstract
  • Essock EA, Sinai MJ, Bowd C, Zangwill LM, Weinreb RN (Sep 2003) Fourier analysis of optical coherence tomography and scanning laser polarimetry retinal nerve fiber layer measurements in the diagnosis of glaucoma., Archives of Ophthalmology, 121 (9), 1238-45 Abstract
  • Bowd C, Zangwill LM, Weinreb RN (Jul 2003) Association between scanning laser polarimetry measurements using variable corneal polarization compensation and visual field sensitivity in glaucomatous eyes., Archives of Ophthalmology, 121 (7), 961-6 Abstract
  • Medeiros FA, Zangwill LM, Bowd C, Bernd AS, Weinreb RN (Jun 2003) Fourier analysis of scanning laser polarimetry measurements with variable corneal compensation in glaucoma., Investigative Ophthalmology & Visual Science, 44 (6), 2606-12 Abstract
  • Johnson CA, Sample PA, Zangwill LM, Vasile CG, Cioffi GA, Liebmann JR, Weinreb RN (Feb 2003) Structure and function evaluation (SAFE): II. Comparison of optic disk and visual field characteristics., American Journal of Ophthalmology, 135 (2), 148-54 Abstract
  • Weinreb RN, Bowd C, Zangwill LM (Feb 2003) Glaucoma detection using scanning laser polarimetry with variable corneal polarization compensation., Archives of Ophthalmology, 121 (2), 218-24 Abstract
  • Racette L, Wilson MR, Zangwill LM, Weinreb RN, Sample PA (May-Jun 2003) Primary open-angle glaucoma in blacks: a review., Survey of Ophthalmology, 48 (3), 295-313 Abstract
  • Bowd C, Chan K, Zangwill LM, Goldbaum MH, Lee TW, Sejnowski TJ, Weinreb RN (Nov 2002) Comparing neural networks and linear discriminant functions for glaucoma detection using confocal scanning laser ophthalmoscopy of the optic disc., Investigative Ophthalmology & Visual Science, 43 (11), 3444-54 Abstract
  • Boehm AG, Bowd C, Vasile C, El-Beltagi TA, Booth M, Zangwill LM, Weinreb RN (Oct 2002) Comparison of two grading methods to evaluate focal narrowing of retinal arterioles in glaucoma., Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie., 240 (10), 810-5 Abstract
  • Weinreb RN, Bowd C, Zangwill LM (Oct 2002) Scanning laser polarimetry in monkey eyes using variable corneal polarization compensation., Journal of Glaucoma, 11 (5), 378-84 Abstract
  • Greenfield DS, Knighton RW, Feuer WJ, Schiffman JC, Zangwill L, Weinreb RN (Jul 2002) Correction for corneal polarization axis improves the discriminating power of scanning laser polarimetry., American Journal of Ophthalmology, 134 (1), 27-33 Abstract
  • Weinreb RN, Bowd C, Greenfield DS, Zangwill LM (Jul 2002) Measurement of the magnitude and axis of corneal polarization with scanning laser polarimetry., Archives of Ophthalmology, 120 (7), 901-6 Abstract
  • Gordon MO, Beiser JA, Brandt JD, Heuer DK, Higginbotham EJ, Johnson CA, Keltner JL, Miller JP, Parrish RK 2nd, Wilson MR, Kass MA, for the Ocular Hypertension Treatment Study Group (Zangwill LM) (Jun 2002) The Ocular Hypertension Treatment Study: baseline factors that predict the, Archives of Ophthalmology, 120 (6), 714-20; discussion 8 Abstract
  • Kass MA, Heuer DK, Higginbotham EJ, Johnson CA, Keltner JL, Miller JP, Parrish RK 2nd, Wilson MR, Gordon MO, for the Ocular Hypertension Treatment Study Group (Zangwill LM) (Jun 2002) The Ocular Hypertension Treatment Study: a randomized trial determines, Archives of Ophthalmology, 120 (6), 701-13; discussion 8 Abstract
  • Lee AC, Sample PA, Blumenthal EZ, Berry C, Zangwill L, Weinreb RN (Jun 2002) Infrequent confirmation of visual field progression., Ophthalmology, 109 (6), 1059-65 Abstract
  • Johnson CA, Keltner JL, Cello KE, Edwards M, Kass MA, Gordon MO, Budenz DL, Gaasterland DE, Werner E, Ocular Hypertension Study Group (Zangwill LM) (Mar 2002) Baseline visual field characteristics in the ocular hypertension treatment, Ophthalmology, 109 (3), 432-7 Abstract
  • Feuer WJ, Parrish RK 2nd, Schiffman JC, Anderson DR, Budenz DL, Wells MC, Hess DJ, Kass MA, Gordon MO, for the Ocular Hypertension Treatment Study Group (Zangwill LM) (Jan 2002) The Ocular Hypertension Treatment Study: reproducibility of cup/disk ratio, American Journal of Ophthalmology, 133 (1), 19-28 Abstract
  • Goldbaum MH, Sample PA, Chan K, Williams J, Lee TW, Blumenthal E, Girkin CA, Zangwill LM, Bowd C, Sejnowski T, Weinreb RN (Jan 2002) Comparing machine learning classifiers for diagnosing glaucoma from standard automated perimetry., Investigative Ophthalmology & Visual Science, 43 (1), 162-9 Abstract
  • Bowd C, Zangwill LM, Blumenthal EZ, Vasile C, Boehm AG, Gokhale PA, Mohammadi K, Amini P, Sankary TM, Weinreb RN (Jan 2002) Imaging of the optic disc and retinal nerve fiber layer: the effects of age, optic disc area, refractive error, and gender., Journal of the Optical Society of America. A, Optics, Image Science, and Vision., 19 (1), 197-207 Abstract
  • Weinreb RN, Bowd C, Zangwill LM (2002) Assessment of the retinal nerve fiber layer of the normal and glaucomatous monkey with scanning laser polarimetry., Transactions of the American Ophthalmological Society, 100, 161-6; discussion 16 Abstract
  • Weinreb RN, Zangwill L (Oct 2001) Retinal nerve fiber layer evaluation in glaucoma., Journal of Glaucoma, 10 (5 Suppl 1), S56-8 Abstract
  • Zangwill LM, Weinreb RN (Oct 2001) Assessment of the optic disc in glaucoma., Journal of Glaucoma, 10 (5 Suppl 1), S59-61 Abstract
  • Brandt JD, Beiser JA, Kass MA, Gordon MO, for the Ocular Hypertension Treatment Study Group (Zangwill LM) (Oct 2001) Central corneal thickness in the Ocular Hypertension Treatment Study, Ophthalmology, 108 (10), 1779-88 Abstract
  • Sanchez-Galeana C, Bowd C, Blumenthal EZ, Gokhale PA, Zangwill LM, Weinreb RN (Oct 2001) Using optical imaging summary data to detect glaucoma., Ophthalmology, 108 (10), 1812-8 Abstract
  • Tannenbaum DP, Zangwill LM, Bowd C, Sample PA, Weinreb RN (Oct 2001) Relationship between visual field testing and scanning laser polarimetry in patients with a large cup-to-disk ratio., American Journal of Ophthalmology, 132 (4), 501-6 Abstract
  • Bowd C, Zangwill LM, Berry CC, Blumenthal EZ, Vasile C, Sanchez-Galeana C, Bosworth CF, Sample PA, Weinreb RN (Aug 2001) Detecting early glaucoma by assessment of retinal nerve fiber layer thickness and visual function., Investigative Ophthalmology & Visual Science, 42 (9), 1993-2003 Abstract
  • Zangwill LM, Bowd C, Berry CC, Williams J, Blumenthal EZ, Sanchez-Galeana CA, Vasile C, Weinreb RN (Jul 2001) Discriminating between normal and glaucomatous eyes using the Heidelberg Retina Tomograph, GDx Nerve Fiber Analyzer, and Optical Coherence Tomograph., Archives of Ophthalmology, 119 (7), 985-93 Abstract
  • Iester M, Mikelberg FS, Courtright P, Burk RO, Caprioli J, Jonas JB, Weinreb RN, Zangwill L (Jul 2001) Interobserver variability of optic disk variables measured by confocal scanning laser tomography., American Journal of Ophthalmology, 132 (1), 57-62 Abstract
  • Blumenthal EZ, Williams JM, Weinreb RN, Girkin CA, Berry CC, Zangwill LM (Dec 2000) Reproducibility of nerve fiber layer thickness measurements by use of optical coherence tomography., Ophthalmology, 107 (12), 2278-82 Abstract
  • Piltz J, Gross R, Shin DH, Beiser JA, Dorr DA, Kass MA, Gordon MO, for the Ocular Hypertension Treatment Study Group (Zangwill LM) (Oct 2000) Contralateral effect of topical beta-adrenergic antagonists in initial, American Journal of Ophthalmology, 130 (4), 441-53 Abstract
  • Keltner JL, Johnson CA, Quigg JM, Cello KE, Kass MA, Gordon MO, for the Ocular Hypertension Treatment Study Group (Zangwill LM) (Sep 2000) Confirmation of visual field abnormalities in the Ocular Hypertension, Archives of Ophthalmology, 118 (9), 1187-94 Abstract
  • Girkin CA, Emdadi A, Sample PA, Blumenthal EZ, Lee AC, Zangwill LM, Weinreb RN (Sep 2000) Short-wavelength automated perimetry and standard perimetry in the detection of progressive optic disc cupping., Archives of Ophthalmology, 118 (9), 1231-6 Abstract
  • Bowd C, Weinreb RN, Lee B, Emdadi A, Zangwill LM (Sep 2000) Optic disk topography after medical treatment to reduce intraocular pressure., American Journal of Ophthalmology, 130 (3), 280-6 Abstract
  • Zangwill LM, Williams J, Berry CC, Knauer S, Weinreb RN (Jul 2000) A comparison of optical coherence tomography and retinal nerve fiber layer photography for detection of nerve fiber layer damage in glaucoma., Ophthalmology, 107 (7), 1309-15 Abstract
  • Zangwill LM, Williams J, Berry CC, Knauer S, Weinreb RN (Jul 2000) A comparison of optical coherence tomography and retinal nerve fiber layer photography for detection of nerve fiber layer damage in glaucoma., Ophthalmology, 107 (7), 1309-15 Abstract
  • Biderman A, Rosenblatt I, Rosen S, Zangwill LM, Shalev R, Friger M, Weitzman S (May 2000) Sex differentials in predictors of mortality for patients with adult-onset diabetes: a population-based follow-up study in Beer-Sheva, Israel., Diabetes Care, 23 (5), 602-5 Abstract
  • Blumenthal EZ, Sample PA, Zangwill L, Lee AC, Kono Y, Weinreb RN (Mar 2000) Comparison of long-term variability for standard and short-wavelength automated perimetry in stable glaucoma patients., American Journal of Ophthalmology, 129 (3), 309-13 Abstract
  • Johnson CA, Cioffi GA, Liebmann JR, Sample PA, Zangwill LM, Weinreb RN (2000) The relationship between structural and functional alternations in glaucoma: A review, Seminars in Ophthalmology, 15, 221-33
  • Zangwill LM, Bowd C, Weinreb RN (2000) Evaluating the optic disc and retinal nerve fiber layer in glaucoma II: Optic Image Analysis, Seminars in Ophthalmology, 15, 206-20
  • Bowd C, Weinreb RN, Zangwill LM (2000) Evaluating the optic disc and retinal nerve fiber layer in glaucoma I: Clinical examination and photographic methods, Seminars in Ophthalmology, 15, 194-205
  • Bowd C, Weinreb RN, Williams JM, Zangwill LM (Jan 2000) The retinal nerve fiber layer thickness in ocular hypertensive, normal, and glaucomatous eyes with optical coherence tomography., Archives of Ophthalmology, 118 (1), 22-6 Abstract
  • Bowd C, Weinreb RN, Williams JM, Zangwill LM (Jan 2000) The retinal nerve fiber layer thickness in ocular hypertensive, normal, and glaucomatous eyes with optical coherence tomography., Archives of Ophthalmology, 118 (1), 22-6 Abstract
  • Mansberger SL, Sample PA, Zangwill L, Weinreb RN (Nov 1999) Achromatic and short-wavelength automated perimetry in patients with glaucomatous large cups., Archives of Ophthalmology, 117 (11), 1473-7 Abstract
  • Bosworth CF, Sample PA, Williams JM, Zangwill L, Lee B, Weinreb RN (Oct 1999) Spatial relationship of motion automated perimetry and optic disc topography in patients with glaucomatous optic neuropathy., Journal of Glaucoma, 8 (5), 281-9 Abstract
  • Zangwill LM, Berry CC, Weinreb RN (Sep 1999) Optic disc topographic measurements after pupil dilation., Ophthalmology, 106 (9), 1751-5 Abstract
  • Zangwill LM, Chang CF, Williams JM, Weinreb RN (Aug 1999) New technologies for diagnosing and monitoring glaucomatous optic neuropathy., Optometry and Vision Science : Official Publication of the American Academy of Optometry., 76 (8), 526-36 Abstract
  • Kono Y, Zangwill L, Sample PA, Jonas JB, Emdadi A, Gupta N, Weinreb RN (Jun 1999) Relationship between parapapillary atrophy and visual field abnormality in primary open-angle glaucoma., American Journal of Ophthalmology, 127 (6), 674-80 Abstract
  • Lee BL, Zangwill L, Weinreb RN (Jun 1999) Change in optic disc topography associated with diurnal variation in intraocular pressure., Journal of Glaucoma, 8 (3), 221-3 Abstract
  • Gordon MO, Kass MA, for the Ocular Hypertension Treatment Study Group (Zangwill LM) (May 1999) The Ocular Hypertension Treatment Study: design and baseline description, Archives of Ophthalmology, 117 (5), 573-83 Abstract
  • Kono Y, Jonas JB, Zangwill L, Berry CC, Weinreb RN (Apr 1999) Agreement of measurement of parapapillary atrophy with confocal scanning laser ophthalmoscopy and planimetry of photographs., Journal of Glaucoma, 8 (2), 105-10 Abstract
  • Weinreb RN, Zangwill LM (Jan-Mar 1999) Imaging technologies for assessing neuroprotection in glaucomatous optic neuropathy., European Journal of Ophthalmology, 9 Suppl 1, S40-3 Abstract
  • Emdadi A, Zangwill L, Sample PA, Kono Y, Anton A, Weinreb RN (Dec 1998) Patterns of optic disk damage in patients with early focal visual field loss., American Journal of Ophthalmology, 126 (6), 763-71 Abstract
  • Weinreb RN, Zangwill L, Berry CC, Bathija R, Sample PA (Dec 1998) Detection of glaucoma with scanning laser polarimetry., Archives of Ophthalmology, 116 (12), 1583-9 Abstract
  • Bathija R, Gupta N, Zangwill L, Weinreb RN (Jun 1998) Changing definition of glaucoma., Journal of Glaucoma, 7 (3), 165-9 Abstract
  • Yucel YH, Gupta N, Kalichman MW, Mizisin AP, Hare W, de Souza Lima M, Zangwill L, Weinreb RN (Apr 1998) Relationship of optic disc topography to optic nerve fiber number in glaucoma., Archives of Ophthalmology, 116 (4), 493-7 Abstract
  • Bathija R, Zangwill L, Berry CC, Sample PA, Weinreb RN (Apr 1998) Detection of early glaucomatous structural damage with confocal scanning laser tomography., Journal of Glaucoma, 7 (2), 121-7 Abstract
  • Anton A, Yamagishi N, Zangwill L, Sample PA, Weinreb RN (Apr 1998) Mapping structural to functional damage in glaucoma with standard automated perimetry and confocal scanning laser ophthalmoscopy., American Journal of Ophthalmology, 125 (4), 436-46 Abstract
  • Anton A, Yamagishi N, Lopez A, Zangwill L, Weinreb RN (1998) Nuevos parametros para la deteccion y localizacion de dano focal en el glaucoma, Sociedad Espanola de Oftalmologia, 73, 431-8
  • Zangwill LM, Williams JM, Weinreb RN (1998) Quantitative methods for evaluating the retinal nerve fiber layer in glaucoma, Ophthalmology Clinics of North America, 11, 233-41
  • Zangwill L, Berry CA, Garden VS, Weinreb RN (Dec 1997) Reproducibility of retardation measurements with the nerve fiber analyzer II., Journal of Glaucoma, 6 (6), 384-9 Abstract
  • Weinreb RN, Zangwill L, Reproducibility of nerve fiber layer thickness measurements., Ophthalmology, 104(10), 1530-1, Oct 1997 Abstract
  • Zangwill L, Irak I, Berry CC, Garden V, de Souza Lima M, Weinreb RN (Aug 1997) Effect of cataract and pupil size on image quality with confocal scanning laser ophthalmoscopy., Archives of Ophthalmology, 115 (8), 983-90 Abstract
  • Yamagishi N, Anton A, Sample PA, Zangwill L, Lopez A, Weinreb RN (May 1997) Mapping structural damage of the optic disk to visual field defect in glaucoma., American Journal of Ophthalmology, 123 (5), 667-76 Abstract
  • Anton A, Zangwill L, Emdadi A, Weinreb RN (Mar 1997) Nerve fiber layer measurements with scanning laser polarimetry in ocular hypertension., Archives of Ophthalmology, 115 (3), 331-4 Abstract
  • Irak I, Zangwill L, Garden V, Shakiba S, Weinreb RN (Nov 1996) Change in optic disk topography after trabeculectomy., American Journal of Ophthalmology, 122 (5), 690-5 Abstract
  • Zangwill LM, van Horn S, de Souza Lima M, Sample PA, Weinreb RN (Oct 1996) Optic nerve head topography in ocular hypertensive eyes using confocal scanning laser ophthalmoscopy., American Journal of Ophthalmology, 122 (4), 520-5 Abstract
  • Asawaphureekorn S, Zangwill L, Weinreb RN (Apr 1996) Ranked-segment distribution curve for interpretation of optic nerve topography., Journal of Glaucoma, 5 (2), 79-90 Abstract
  • Weinreb RN, Shakiba S, Sample PA, Shahrokni S, van Horn S, Garden VS, Asawaphureekorn S, Zangwill L (Dec 1995) Association between quantitative nerve fiber layer measurement and visual field loss in glaucoma., American Journal of Ophthalmology, 120 (6), 732-8 Abstract
  • Weinreb RN, Shakiba S, Zangwill L (May 1995) Scanning laser polarimetry to measure the nerve fiber layer of normal and glaucomatous eyes., American Journal of Ophthalmology, 119 (5), 627-36 Abstract
  • Zangwill L, Shakiba S, Caprioli J, Weinreb RN (Apr 1995) Agreement between clinicians and a confocal scanning laser ophthalmoscope in estimating cup/disk ratios., American Journal of Ophthalmology, 119 (4), 415-21 Abstract
  • Forman MR, Hundt GL, Berendes HW, Abu-Saad K, Zangwill L, Chang D, Bellmaker I, Abu-Saad I, Graubard BI (Mar 1995) Undernutrition among Bedouin Arab children: a follow-up of the Bedouin Infant Feeding Study., The American Journal of Clinical Nutrition, 61 (3), 495-500 Abstract
  • Tsai CS, Zangwill L, Gonzalez C, Irak I, Hoffman R, Weinreb RN (1995) Ethnic differences in optic nerve head topography, Journal of Glaucoma, 4, 248-57
  • Tsai CS, Zangwill L, Sample PA, Garden V, Bartsch D, Weinreb RN (1995) Correlation of peripapillary retinal height and visual field in glaucoma and normal subjects, Journal of Glaucoma, 4, 110-6
  • David R, Zangwill L, Briscoe D, Dagan M, Yagev R, Yassur Y (May 1992) Diurnal intraocular pressure variations: an analysis of 690 diurnal curves., The British Journal of Ophthalmology, 76 (5), 280-3 Abstract
  • Naggan L, Forman MR, Sarov B, Lewando-Hundt G, Zangwill L, Chang D, Berendes HW (Oct 1991) The Bedouin Infant Feeding Study: study design and factors influencing the duration of breast feeding., Paediatric and Perinatal Epidemiology, 5 (4), 428-44 Abstract
  • Chernichovsky D, Zangwill L (1990) Microeconomic theory of the household and nutrition programs, Food and Nutrition Bulletin, 12, 34-52
  • Cooper GS, Zangwill L (May-Jun 1989) An analysis of the quality of research reports in the Journal of General Internal Medicine., Journal of General Internal Medicine : Official Journal of the Society for Research and Education in Primary Care Internal Medicine., 4 (3), 232-6 Abstract
  • David R, Zangwill L, Badarna M, Yassur Y (1988) Epidemiology of retinal vein occlusion and its association with glaucoma and increased intraocular pressure., Ophthalmologica. Journal International D'ophtalmologie. International Journal of Ophthalmology. Zeitschrift Fur Augenheilkunde., 197 (2), 69-74 Abstract
  • David R, Zangwill L, Stone D, Yassur Y (Oct 1987) Epidemiology of intraocular pressure in a population screened for glaucoma., The British Journal of Ophthalmology, 71 (10), 766-71 Abstract
  • David R, Zangwill L, Rosenblatt I, Yassur Y (1986) The association of optic disc appearance and ocular, systemic and environmental factors, New Trends in Ophthalmology, 1, 244-52
  • David R, Zangwill LM, Tessler Z, Yassur Y (Dec 1985) The correlation between intraocular pressure and refractive status., Archives of Ophthalmology, 103 (12), 1812-5 Abstract
  • Gross J, Goldsmith JR, Zangwill L, Lerman S (Jan 1984) Monitoring of hospital emergency room visits as a method for detecting health effects of environmental exposures., The Science of the Total Environment, 32 (3), 289-302 Abstract

Profile Details

Last Updated: 3/13/2009

COS Expertise ID #546820
Reference this profile directly: http://myprofile.cos.com/zangwill20